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Motility Midterm
Fixation Eye Movement Lecture
39
Medical
Professional
09/24/2008

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Term
Vernal keratoconjunctivitis
Definition
covers the entire superior tarsus and there is often a ropy adherent mucous discharge
Term
Fovea
Definition
~0.3degree
Term
Parietal Lobe Neurons
Definition
discharge during steady fixation but not during pursuit of a moving target
Term
The threshold for electrical stimulation of saccades in the
Definition
frontal eye fields and superior colliculus is elevated
Term
Micro stimulation of neurons from where affect the speed of ongoing pursuit but does not pr9duce pursuit if the object of regard is stationary
Definition
medial superior temporal visual area or in the dorsolateral pontine nucleus
Term
How many types of eye movements take place during attempted fixation
Definition
Three: Tremor, Drift, Microsaccade
Term
Average amplititude for tremor
Definition
20 sec of arc
Term
Tremor velocity may be as high as
Definition
30 in arc per second
Term
Drift
Definition
a low velocity movement, typically 1 to 8 min arc per second with a mean of 5 min arc per second (15 cones per second)
Term
Describe drifts movement
Definition
irregular and of variable low frequency.
Term
Drift’s amplitude is
Definition
typically 1-5 min arc
Term
Drift makes up more than what percentage of ones total fixation time
Definition
95%
Term
Microcosaccade
Definition
have a frequency of occurrency of 1 to 2 per second
Term
Microsaccades or binocular or monocular
Definition
binocular; which suggest that they are under central neurologic control
Term
Drift component is determined
Definition
in darkness
Term
What is the time constant with the slow leaky neural integrator hypothesis in gaze holding phenomenon
Definition
70 seconds
Term
Dirft
Definition
small (miniature) eye movement during attempted fixation)
Term
Spatial localization can be correlated with the duration of fixation generally within a
Definition
+/- 5 min arc
Term
The velocity of drift will determine
Definition
if you have a saccade or drift
Term
Fixation – Drifts
Definition
slow velocity irregular component eye movement (considered to represent smooth pursuit eye movement in response to retinal image slip
Term
Average velocity and range of fixation – drift
Definition
~5 in arc per sec ~15 cone diameter, range of 1-8 min arc per sec
Term
Amplitude and frequency of drift
Definition
1.5 min of arc, <0.5 Hz
Term
Drifts are error-____
Definition
producing mechanism but can serve as an error reducing mechanism
Term
Drifts are _____ (not/are) correlated between both eyes.
Definition
Not
Term
Drifts represent noise of
Definition
ocularmotor system
Term
What is average amplitutude, range, and duration of microsaccades
Definition
average amplitude – 5 min arc, range 1-25 min arc, duration 10-25 msec
Term
Peak velocity profile for microsaccade
Definition
typically 1-20 deg/sec that fits the main sequence
Term
In the dark accuracy of fixation is dependent on
Definition
drift velocity
Term
In order for corrective saccade to be initiated the drift velocity must be
Definition
0.6 deg/sec
Term
Probability of occurrence of a microsaccade increases with
Definition
eccentricity of gaze (100% - 6 min of arc)
Term
Frequency, average amplitude, velocity of Tremor
Definition
High frequency movements typically ranging from 30-100 Hz, average amplitutude – 20 arsec (range 5-30), Velocity of tremor -
Term
How is tremor related to frequency
Definition
inversely proportional. Is not correlated between the two eyes, does not have central origin. It appears to represent a state of incomplete partial tetanus and has No effect on vision.
Term
The most important nuclei for horizontal gaze holding phenomenon are
Definition
NPH (Nucleus Prepositus Hypoglossi) , MVN (Medial Vestibular Nucleus for Horizontal Eye movements), Cerebellar flocculus and posterior vermis
Term
Gaze holding depends upon connection between
Definition
brainstem nuclei (NPH, MVN for horizontal movements and interstitial nucleus of cajal for vertical movements) and the cerebellum
Term
The role of the Neural integrator
Definition
is to convert phasic velocity commands encoded in the saccadic, vestibular optokinetic or pursuit systems into step position commands, causing tonic contractions of the extraocular muscles.
Term
Microsaccades are caused by
Definition
drifts (to move the fixation back on the original position)
Term
How does the brainstem encode signals
Definition
1. The discharge frequency of an ocular motor neuron is linearly proportional to eye position during fixation 2.Ocular motor neurons modulate their discharge in proportion to eye velocity. 3. Combined velocity and position signals are necessary to compensate for the restrictions imposed upon the eye by the mechanical properties of the orbital contents: A) Viscous drag slows down eye movements B) Elastic-restoring forces pull the eye back towards primary position.
Term
The neurologic substrate involved in neural integrating and related gaze holding function consist of the nucleus
Definition
prepositus hypoglossi and medial vestibular nucleus for horizontal conjugate movements and probably the interstitial nucleus of Caja for vertical conjugate movements
Term
Gazed evoked nystagmus
Definition
when there is a leaky integrator. An imperfection.
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