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Molecular Cell Biology 1
UCF Summer 2012 MCB Sotero
13
Biology
Undergraduate 4
07/03/2012

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Cards

Term
 The Cell Theory
Definition

  1. All Living Organisms are made up of 1 or more cells
  2. The Cell is the fundamental unit of structure & function in all living organisms
  3. All cells are essentially the same in chemical composition.

 

Term

The Process

in the

Miller-Urey Experiment

Definition

1. 7 simple molecules (H20, N2, NH3, CO2, CH4 & H2 (NO O2)

2. Heat: to evaporate water

3. Radiation (Electric Discharge): provides NRG

4. Cooling System: Caputures molecules in liquid form for examination

Term
The Central Dogma
Definition

The flow of genetic information from DNA (replication) to RNA(transcription) to Protein(translation).

Term
The simple organic molecules that resulted from the Miller-Urey experiment.
Definition
  1. Alanine
  2. Asparic Acid
  3. Glutamic Acid
  4. Glycine
  5. Urea
  6. Lactic Acid
  7. Acetic Acid
  8. Formic Acid
Term
What did the Miller-Urey Experiment suggest?
Definition
Organic molecules could form under the conditions that existed in the primitive earth.
Term
Results of Miller-Urey Experiment
Definition

With each round of heating, radiation and cooling, more complex organic molecules were formed.  These are:

  1. Aldehydes
  2. Simple Acids
  3. More complex Acids including amino acids
Term
Self-Replicating Macromolecules
Definition
  1. Necessary for reproduction and evolution.
  2. Present day: nulceic acid
  3. Past: possibly RNA based
Term
Evidence of an RNA World
Definition
  1. Some RNA molecules of enzymatic activity
  2. RNA can catalyze the polymerization of nucleotides, including the synthesis of complementary RNA by using itself as a template. (not observed in DNA)

 

Term
Ribozyme
Definition
An RNA molecule that possesses enzymatic activity.
Term
Ribozyme-catalyzed RNA cleavage
Definition

The ribozyme & the substrate may be 2 domains of the same RNA molecule.

Observed in:

  • Genome replication in some RNA viruses
  • Intron splicing
Term
Did DNA, RNA or proteins come first?
Definition

First, RNA based system 

Second, RNA & protein based system

Today, Central dogma

Term
The first cell
Definition
A self replicating RNA and other life promoting molecules inside a phospholipid membrane.
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