Term
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Definition
| Prevent cross-linkage of NAM and NAG |
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Term
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Definition
| Interferes with transportation of peptidoglycan components across inner plasma membrane. |
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Term
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Definition
| Prevent cross-linkage of NAM and NAG. |
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Term
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Definition
| Blocks attachment of 4 amino acids to NAM sugars. |
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Term
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Definition
| Inhibits synthesis of mycolic acid. |
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Term
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Definition
| Binds to 30s ribosomal subunit and causes it to change shape. mRNA is incorrectly read and nonsense protein synthesized. |
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Term
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Definition
| Binds to 30s robomosal subunit and blocks binding of mRNA to tRNA at the A site. Elongation and translation stops. |
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Term
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Definition
| Binds to 50s ribosomal sununit and inhibits formaiton of peptide bonds between amino acids. Elongation and translocation stops. |
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Term
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Definition
| Binds to 50s ribosomal subunit and prevents translocation of tRNA's between P and A sites. Elongation and translocation stops. |
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Term
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Definition
| Binds to 50s ribosomal subunit and inhibits joining of ribosomal subunits. No functional 70s ribosome produced. |
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Term
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Definition
| Inhibits DNA gyrase so bacterial chromosome remains supercoiled. Prevents DNA replication. |
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Term
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Definition
| Detergent-like effect. Disrupts phosopholipid bilayer. |
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Term
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Definition
| Pteridine synthetase inhibition. Blocks PABA to dihydrofolic acid. |
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Term
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Definition
| Dihydrofolate reductase inhibition. Blocks dihydrofolic acid to tetrahydrofolic acid. |
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Term
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Definition
| Binds to ergosterol in cell membrane and creates pores. Nutrients leave through pores and fungi dies. |
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Term
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Definition
| Inhibits metabolic pathway so correct form of ergosterol in not synthesized. |
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Term
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Definition
| Interferes with enzyme that attaches to B-glucan. B-glucans not linked to fungal cell wall, so cell is more susceptible to lysis. |
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Term
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Definition
| Prevents conversion of toxic heme to nontoxic heme. Toxic heme accumulates and kills protozoan. |
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Term
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Definition
| (Blocks HIV entry into cell) Inhibits activity of reverse transcriptase. HIV cannot synthesize the nucleic acids it requires for viral replication. |
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