Term
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Definition
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Term
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Definition
| Stimulates open complex at oriC |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Stabilizes and protects single stranded DNA |
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Term
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Definition
| Synthesizes lagging strand RNA primers, RNA priming |
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Term
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Definition
| Chromosome replication: consisting of Poly 3 core, β clamp, and complex clamp loader |
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Term
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Definition
| DNA repair and Okazaki fragment processing: removes RNA |
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Term
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Definition
Okazaki fragment processing:
joins segements DNA sealing |
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Term
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Definition
Methylates adenines in GATC
sequences |
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Term
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Definition
Binds Hemimethylated GATC,
inhibits oriC |
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Term
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Definition
| Induces DnaA to hydrolyze ATP |
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Term
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Definition
| Participates in replication termination |
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Term
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Definition
| Decatenates completed chromosomes |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Chromosomal Translocation |
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Definition
Fusion gene
(ex. philadelphia chromosome) |
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Term
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Definition
| adding water to bases/ Nitrous Acid |
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Term
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Definition
| Removing an A or G from backbone |
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Term
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Definition
| Pyrimidne dimers & 6-4 photoproducts |
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Term
| Mismatch repair is done by: |
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Definition
| MUT (only the unmethylated strand) |
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Term
| Photo repair of a pyrimidine dimer |
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Definition
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Term
| Repair of methylated nucleotide bases |
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Definition
| Methyltransferase removes the methyl group |
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Term
| Reactive Oxygen Species (Hydrogen peroxide, superoxide, hydroxyl) cause: |
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Definition
| 8-oxoG and transversion mutation (A pairs with C) |
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Term
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Definition
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Term
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Definition
| Binds DNA, promotes branch migration |
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Term
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Definition
| DNA translocase, promotes branch migration |
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Term
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Definition
| Resolvase, resolves Holliday intermediate |
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Term
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Definition
| form 3' strand extension (B=3'-5' & D=5'-3') |
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Term
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Definition
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Term
| Translation initiation:Prokaryotes vs Eukaryotes |
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Definition
Pro: Shine-Dalgarno, Fmet, IF, ribosomal rec of ribosomal binding site
Euk: Kozak seq, Met, eIF, Poly A interacts with 5'cap |
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Term
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Definition
| binds a transcription activator/ repressor- causing conformational change |
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Term
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Definition
| Protein binding to operator/ regulatory sequence blocking transcription |
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Term
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Definition
| DNA region interacting with repressor to control expression of genes |
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Term
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Definition
| Consists of one or more related genes + operator and promoter |
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Term
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Definition
| Positive regulator increasing transcription rates ; positive modulator |
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Term
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Definition
| DNA sequence where RNA polymerase may bind to initiate transcription |
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Term
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Definition
| Protein affecting regulation and transcription initiation of a gene by binding to a regulatory sequence, interacting with RNA polymerase |
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Term
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Definition
| Protein stimulating transcription by binding both RNA polymerase and activator without binding DNA directly |
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Term
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Definition
| mediate protein-protein interactions in eukaryotic transcription |
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Term
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Definition
| activates CRP, which binds to operon. low levels of glucose=high levels of cAMP |
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Term
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Definition
| repressor (when absent) and activator (when present binds to AraC) |
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Term
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Definition
| high tryptophan=repression of TRP operon |
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