Term
| Partial mu, full kappa agonist |
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Definition
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|
Term
| mu antagonist, full kappa agonist |
|
Definition
|
|
Term
| Partial mu, full kappa antagonist |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
partial mu, full kappa agonist
less resp. depression
less euphoria, dysphoria at high doses
less constipation than morphine
less abuse potential |
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|
Term
|
Definition
mu antagonist, full kappa agonist
less resp. depression
less dysphoria than pentazocine
same constipation as pentazocine |
|
|
Term
|
Definition
partial mu, full kappa agonist
less resp. depression
less dysphoria
increases BP |
|
|
Term
|
Definition
partial mu, full kappa antagonist
less resp. depression
some euphoria
longer duration of action compared to apparent half-life |
|
|
Term
|
Definition
partial mu
minimal resp. depression/constipation
less tolerance and dependence
inhibits 5-HT and NE transporters
only partly blocked by naloxone |
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|
Term
|
Definition
selective kappa agonist
too much dysphoria, not enough analgesia
not used |
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