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Mitochondria & Adipose Lab 7
UC Med 2015
16
Medical
Graduate
10/19/2011

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Cards

Term
When looking at a mitochondria, what are the main things that need to be identified?
Definition
1)outer mitochondrial membrane
2)inner mitochondrial membrane
3)intermembrane-membrane space
4)matrix
5)cristae
6)matrix granules
Term
What is located on the inner mitochondrial membrane?
Definition
1) cytochromes
2) dehydrogenases
3) flavoproteins
Term
What are the two morphologies of mitochondria?
Definition
1) condensed configuration
2) orthodox configuration
Term
What does the condensed configuration of mitochondria refer to?
Definition
high levels of oxidative phosphorylation
Term
What does the orthodox configuration of mitochondria refer to?
Definition
low levels of oxidative phosphorylation
Term
What type of cells have mitochondria with tubular cristae?
Definition
steroid secreting cells
Term
What type of cells have mitochondria with triangular cristae?
Definition
astrocytes(glial cells found in the brain and spinal cord)
Term
Where will you typically find mitochondria in the cell?
Definition
Near sites of high ATP utilization
Term
What is termed unilocular adipose tissue because each cell contains a single large droplet of fat, which displaces other organelles to the cell periphery?
Definition
White adipose tissue (WAT)
Term
What cell contains many fat droplets, thus termed multilocular fat?
Definition
Brown adipose tissue (BAT)
Term
Is WAT and BAT poorly vascularized?
Definition
No way, its richly vascularized(you should be able to see many small blood vessels when looking at a slide)
Term
When a thymus involutes with age, what grows to replace the tissue?
Definition
WAT
Term
At body temparture, fat droplets are...
Definition
liquid
Term
If looking at a SEM, what (collagen type) can be seen emeshing WAT cells?
Definition
reticular fibers (Collagen III)
Term
What protein can only be found in brown adipose tissue and with proper staining is why the tissue type is borwn?
Definition
Uncoupling protein (UCP-1- it dissipates the proton gradient before it can be used to provide the energy for oxidative phosphorylation, resulting in the production of heat instead of ATP
Term
Which fat type is more vascularized?
Definition
BAT- for distrubtion of the heat
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