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Micronutrients
10/14/11 Third Lecture
16
Medical
Graduate
10/15/2011

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Cards

Term
What is the primary roles of micronutrients?
Definition
To enhance catalytic diversity of enzymes, provide structural elements, sense light in vision, and signaling
Term
What are vitamins?
Definition
Organic compounds that occur naturally in food and must be consumed to maintain growth, health, and reproduction
Term
What is the difference between water soluble and non water soluble vitamins in terms of toxicity? What are the 3 groups of water soluble vitamins?
Definition
1. Water soluble are non toxic (can be excreted easily in urine)

2. Energy releasing, 1 carbon transfer, and antioxidant vitamins
Term
What are the physiologic roles of Thiamine (B1) and the diseases of deficiency
Definition
Physiologic role: Coenzyme in breakdown of carbs and branched amino acids

Deficiency: Polyneuritis, wenicke-korsakoff
Term
What are the physiologic roles of Riboflavin (B2) and the diseases of deficiency
Definition
Physiologic: Coenzyme in redox reactions

Deficiency: Cheilosis, angular stomatitis, dermatitis
Term
What are the physiologic roles of Niacin and the diseases of deficiency
Definition
Physiologic roles: Proton transfer with dehydrogenases

Deficiency: Pellagra with diarrhea, dermatitis, and dementia
Term
What are the physiologic roles of Pyridoxine (B6) and the diseases of deficiency
Definition
Pysiological: Coenzyme in amino acid, glycogen, and sphingoid metabolism

Deficiency: Nasolateral seborrhea, glossitis, neuropathy
Term
What are the physiologic roles of Biotin and the diseases of deficiency
Definition
Physiologic: Coenzyme in bicarbonate dependent carboxylations

Deficiency: Fatigue, despression, nausea, dermatitis, muscular pains

Note: Critical component in the synthesis of oxaloacetic acid, so it plays a big role in altering TCA activity
Term
What are the physiologic roles of Pantothenic acid and the diseases of deficiency
Definition
Physiological: Constituent of CoA

Deficiency: Fatigue, sleep disturbances, impaired coordination, nausea
Term
What are the physiologic roles of Folacin (Folic acid) and the diseases of deficiency
Definition
Physiologic: Coenzyme in single carbon transfers of nucleic acid and amino acid synthesis

Deficiency: Birth defects, Magaloblastic anemia
Term
What are the physiologic roles of Vitamin B12 and the diseases of deficiency
Definition
Coenzyme in metabolism of odd number fatty acids and methyl transfers

Deficiency: Pernicious anemia, neuro disorders, and dementia

Note: Deficiency most commonly caused by autoimmune destruction of parietal cells that produce the intrinsic factor for B12's absorption
Term
What are the physiologic roles of Vitamin C and the diseases of deficiency
Definition
Physiologic: Formation of collagen and carnitine, antioxidant

Deficiency: Scurvy, bleeding and spongy gums, poor wound healing
Term
What are the fat soluble vitamins?
Definition
A D E K
Term
What are the physiologic roles of Vitamin A and the diseases of deficiency and excess
Definition
Physiologic: Visual pigments, cell differentiation and proliferation

Deficiency: Night blindness, 2 others i cant even pronounce

Excess: Dirst defects, vomiting, bone abnormalities
Term
What are the physiologic roles of Vitamin D and the diseases of deficiency and excess
Definition
Physoilogic: Absorption of calcium and mineralization of bones and teeth

Deficiency: Rickets and osteomalacia

Excess: Nausea, vomiting, anorexia, diarrhea, calcification of soft tissue
Term
What are the physiologic roles of Vitamin E and the diseases of deficiency and excess
Definition
Physiologic: Antioxidant for membranes, lipids, and LDL

Deficiency: Anemia, nerve and muscle degeneration

Excess: Relatively non toxic
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