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Microbiology
20
27
Biology
Undergraduate 3
09/18/2008

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Term
Sulfonamides
Definition
synthetic
inhibit folic acid synthesis
Term
Paul Ehrlich
Definition
discovered first chemotherapeutic agent called salvarsan
Term
Dubos
Definition
discovered antibiotic gramicidin from soil bacillus
Term
Waksman
Definition
discovered antibiotic streptomycin from soil streptomyces
Term
3 methods of antiviral drugs
Definition
1. idoxuridine & purine analogs (acyclovir)
2. prevent uncoating
3. activate antiviral mechanisms
Term
MIC
Definition
minimum inhibitory concentration
lowest concentration of chemotherapeutic agent that prevents growth
Term
MBC
Definition
minimum bactericidal concentration
lowest concentration of agent that results in now growth upon subculture
Term
ethambutol
Definition
synthetic
competitive inhibitor
tuberculosis
Term
Isoniazid
Definition
synthetic
vitamin b6 analog
tuberculosis
Term
Amantadine
Definition
synthetic
prevents viral entry/uncoating
influenza A
Term
Griseofulvin
Definition
antibiotic
inhibits mitosis
antifungals
Term
niclosamide
Definition
synthetic
inhibits oxidative phosphorylation
tapeworms
Term
polyenes
Definition
antibiotic
injure plasma membrane
fungicide
Term
natural penicillin
Definition
antibiotic
inhibits cell wall synthesis
gram + bacteria
Term
synthetic penicillin
Definition
antibiotic
inhibit cell wall synthesis
broad spectrum
Term
tetracyclines
Definition
antibiotic
inhibit protein synthesis
broad spectrum
Term
cephalosporins
Definition
antibiotic
inhibit cell wall synthesis
broad spectrum
Term
carbapenems
Definition
antibiotic
inhibit cell wall synthesis
broad spectrum
Term
polypeptides
Definition
antibiotic
inhibit cell wall synthesis, injure plasma membrane
gram+ and - bacteria
Term
vancomycin
Definition
antibiotic
inhibit cell wall synthesis
penicillin resistant staph
Term
fluoroquinolones
Definition
synthetic
inhibit DNA synthesis
UTIs
Term
Zidovudine
Definition
synthetic
inhibit DNA synthesis
AIDS
Term
Rifamycins
Definition
antibiotic
inhibit mRNA synthesis
tuberculosis
Term
aminoglycosides
Definition
antibiotic
inhibit protein synthesis
gram- bacteria
Term
chloramphenicol
Definition
antibiotic
inhibit protein synthesis
life-threatening infection
Term
macrolides
Definition
antibiotic
inhibit protein synthesis
gram- bacteria
Term
trimethoprim
Definition
synthetic
inhibit folic acid synthesis
pneumocytis & UTIs
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