Shared Flashcard Set

Details

Microbiology
Case Studay #4 - Can't Beat the Cough
11
Biology
Undergraduate 1
11/25/2007

Additional Biology Flashcards

 


 

Cards

Term
What are two common names of the disease?
Definition
  • Whooping cough
  • Pertussis
Term
What was the organism's species name?
Definition
Bordetella pertussis
Term
What are the characteristics of the MO?
Definition
  • GM-
  • Coccobacillus
  • Aerobic
  • Nonmotile
Term
What is the mode of tranmission?
Definition
  • Direct contact or
  • Respiratory droplet
Term
What two virulance factor does the MO posses?
Definition
  • Filamentous hemagglutinin - attaches to tracheal cells causing binding and colonization
  • Petussis toxin - helps in adhesion and interferes with the metabolism of epithelial cells causing excessive mucous.
Term
What are the early symptoms of the disease?
Definition
Runny nose, sore throat, watery eyes and fatigue
Term
What is the classic sign of the disease and when to it exhibit?
Definition
Paroxysmal cough at the paroxysmal stage (late)
Term
When is the patient most contagious?
Definition
Early stage, catarrhal, when MO is most abundant - 1 to 2 weeks.
Term
What is the name of the vaccine used to treat pertussis?
Definition
DPat (Diphtheria Tetanus acellular Pertussis)
Term
Why doesn't it protect into adulthood?
Definition
Last booster is given at age 7 and is only protective for a decade or two.
Term
Why after 6 weeks is a throat culture an ineffective means of diagnosis?
Definition
  • MO abundance is signficantly reduced.
  • Only blood test for Abs is effective.
Supporting users have an ad free experience!