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Microbiology
viruses-4
24
Biology
Undergraduate 1
07/15/2007

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Term
in vivo
Definition
inoculation of laboratory bred animals and embryonic bird tissues
Term
in vitro
Definition
cell or tissue culture methods
Term
the primary purposes of viral cultivation
Definition
to isolate and identify viruses in clinical specimens
to prepare viruses for vaccines
to do detailed research on viral structure, multiplication cycles, genetics, and effects on host cells
Term
monolayer
Definition
single confluent sheet of cells that supports viral multiplication and permits close inspection of the culture for signs of infection
Term
primary cell cultures
Definition
prepared by placing freshly isolated animal tissue in a growth medium
Term
plaques
Definition
cleawr-well-defined patches in teh cell sheet
Term
creutzfeldt jakob
Definition
afflicts the central nervous system of humans and causes gradual egeneration and death
Term
adeno associated virus
Definition
can replicate only in cells infected with adenovirus
Term
viroids
Definition
parasitize plants-different from ordinary viruses and only composed of naked strands of rna-lack a capsid or other coatings
Term
azidothymide-AZT
Definition
used to treat aids-targets the synthesis stage
Term
passive immunization
Definition
patient is given preformed antibodies-immunotherapy
Term
active immunization
Definition
vaccinated with a microbe or its antigens providing a form of advance protection
Term
sera produced in horses is available to treat botulism, diphtheria, and spider/snake bites
Definition
true
Term
vaccination
Definition
exposing a person to material that is antigenic but not pathogenic
Term
the salk poliovirus vaccine contains what type of virus
Definition
inactivated
Term
attentuation
Definition
any process that substantially lessens or negates the virulence of viruses or bacteria
Term
mumps, measles, polio(sabin) and rubella contain_____viruses
Definition
live, nonvirulent viruses
Term
disadvantages of using live microbes
Definition
require special storage facilities
can be transmitted to other people
can conceivably mutate back to a virulent strain
Term
what are vaccines for bacteria called?
viruses?
Definition
acellular or subcellular vaccines
subunit vaccines
Term
toxoid
Definition
consists of a purified bacterial exotoxin that has been chemically denatured
Term
dna vaccines
Definition
being hailed as the mosdt promoising of all of the newer approaches to immunization
dna inserted into a plasmid vector and inoculateed into the human
Term
in dna vaccines, how is the microbial dna expressed
Definition
proteins-this allows them to recognize that they are foreign and commit them to memory
Term
name five vaccines that are inactivated whole viruses
Definition
poliomyelitis(salk)
rabies
influenza
japanese encephalitis
hepatitis A
Term
what is a benefit of oral administration of a vaccine
Definition
stimulates protection on the mucous membrane of the portal of entry
easier to give; more accepted
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