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Microbiology
Basic bacteriology
175
Microbiology
Graduate
01/17/2014

Additional Microbiology Flashcards

 


 

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Term
E coli virulence factors
Definition
fimbriae; K capsule; CPS endotoxin
Term
invades intestinal mucosa and causes necrosis and inflamamtion
Definition
EIEC
Term
E coli that causes dystentary
Definition
EIEC, EHEC
Term
E coli with no toxins
Definition
EIEC, EPEC
Term
E coli similar to shigella
Definition
EIEC
Term
labile/stabile toxin
Definition
ETEC
Term
E coli that causes traveler's diarrhea
Definition
ETEC
Term
adheres to apical surface, flattens villi and prevents absorption
Definition
EPEC
Term
e coli that causes diarrhea in children
Definition
EPEC
Term
shiga like toxin
Definition
EHEC
Term
E coli that causes HUS
Definition
EHEC: O157H7
Term
endothelium swell and narrows lumen leading to mechanical hemolysis and reduced renal blood flow
Definition
EHEC
Term
E coli that does not ferment sorbitol
Definition
EHEC
Term
4 A's of klebsiella
Definition
Aspiration pneumonia, Abscess in lungs and liver, alcoholics, diabetics
Term
currant jelly sputum
Definition
klebsiella
Term
nosocomial UTIs
Definition
Klebsiella
Term
diarrhea to avoid abx
Definition
salmonella
Term
rose spots, fever, HA and diarrhea
Definition
Salmonella typhi
Term
uses actin polymerization to propel
Definition
shigella
Term
fecal oral through poultry meat and unpasteurized milk
Definition
campylobacter
Term
common antecedent to guillain barre
Definition
campylobacter
Term
comma or s shaped, oxidase positive
Definition
campylobacter, vibrio cholera
Term
rice water stools
Definition
vibrio cholera
Term
pet feces
Definition
yerisinia enterocolitica
Term
mimics appendicitis
Definition
Yersinis enterocolitica,
Term
day care centers
Definition
yersinia enterocolitica
Term
toxin A of c diff
Definition
binds the brush border
Term
toxin B of c diff
Definition
cytotoxin, destroys cytoskeletal structure or enterocytes
Term
diarrhea secondary to antibiotic use
Definition
C diff
Term
gram positive branching filaments; anaerobe
Definition
actinomyces
Term
gram positive branching filaments, aerobe
Definition
nocardia
Term
gram positive rods
Definition
clostridium, corynebacterium, listeria, bacillus
Term
gram positive cocci; catalase+
Definition
staphylococcus
Term
gram+ cocci; catalase-
Definition
streptococcus
Term
gram+ cocci; coag+
Definition
s aureus
Term
gram+ cocci, coag-
Definition
novobiocin S = S epidermidis
Novobiocin R = S saphrophyticus
Term
alpha hemolytic gram positive
Definition
S pneumo= capsule, bile soluble Optochin S
Viridans = no capsulre, optochin R, bile insoluble
Term
beta hemolytic bacteria
Definition
GAS = bacitracin S
GBS = bacitracin R
s aureus = catalase and coag+
listeria
Term
gamma hemolytic
Definition
enterococcus
Term
protein A
- organism
- fxn
Definition
- S aureus
- binds Fc-IgG inhibiting complement fixation
Term
inflammatory diseases of S aureus
Definition
skin infections, organ abscesses, pneumonia
Term
toxic mediated diseases of S aureus
Definition
toxic shock syndrome, scalded skin syndrome, rapid onset food poisoning
Term
infects prosthetic devices by producing adherent biofilms
Definition
S epidermidis
Term
normal skin flora
Definition
S epidermidis
Term
S pneumo most common cause of:
Definition
meningitis, otitis media (children), pneumonia, sinusitis
Term
lancet shaped gram+ diplococci
Definition
S pneumo
Term
contains IgA protease
Definition
S pneumo
Term
rusty sputum
Definition
S pneumo
Term
normal flora of mouth
Definition
viridans
Term
subacute endocarditis
Definition
viridans
Term
pyogenic disease of GAS
Definition
pharyngitis, cellulitis, impetigo
Term
toxigenic disease of GAS
Definition
scarlet fever, toxic shock like syndrome
Term
immunologic diseases of GAS
Definition
rheumatic fever, acute glomerulonephritis
Term
GBS disease in newborns
Definition
pneumonia, meningitis and sepsis
Term
CAMP factor
- organism
- fxn
Definition
- GBS
- enlarges area of hemolysis formed by S aureus
Term
screen pregnant women at 35-37 weeks for
Definition
GBS
Term
normal colonic flora, gamma hemolytic
Definition
enterococcus
Term
UTI and subacute endocarditis
Definition
enterococci
Term
biliary tract infections
Definition
enterococci
Term
bactermia and subacute endocarditis in colon cancer pts
Definition
s bovis
Term
ADP ribosylationof EF2 -> psuedomembranous pharyngitis
Definition
diphtheria toxin
Term
metachromatic granuls
Definition
C diptheria
Term
Elek test for toxin
Definition
diphtheria
Term
spore forming bacteria
Definition
B anthracis, C perfringens, C tetani, B cereus, C botulinum and C burnetti
Term
Infect renshaw cells in spinal cord
Definition
C tetani
Term
spores in honey
Definition
C botulinum
Term
flabby baby syndrome
Definition
C botulinum
Term
lock jaw
Definition
C tetani
Term
cutaneous vs pulmnoary anthrax
Definition
cutaneous = contact -> black eschar (painless ulcer)
pulmonary = inhalation -> fever, pulmonary hemorrhage, mediastinitis and shock
Term
contains lethal factor and edema factor
Definition
B anthracis
Term
ingestion of unpasteurized milk/cheese
Definition
listeria and brucella
Term
actin rockets to move from cell to cell
Definition
listeria
Term
listeria infections in pregnant women
Definition
amnionitis, septicmia, spont abortion
Term
listeria infections in newborns
Definition
granulomatosis infantiseptica, neonatal meningitis
Term
listeria in IS pt
Definition
meningitis
Term
listeria in normal healthy pt
Definition
gastroenteritis
Term
spirochete bacteria
Definition
borrelia, leptospira and treponema
Term
aniline dyes
Definition
borrelia
Term
dark-field microscopy
Definition
treponema
Term
question mark shaped bacteria
Definition
leptospira
Term
animal urine
Definition
leptospira and hantavirus
Term
jaundice, photophobia with conjunctivitis
Definition
leptospira
Term
Weil's disease
Definition
jaundice and azotemia from liver and kidney dysfxn with leptospira
Term
stages of lyme disease
Definition
1 = erythema chronic migrans, flu-like
2- neurologic (bell's) and cardiac (AV block)
3 = chronic mono arthritis and migratory poylyarthritis
Term
area of lyme disease
Definition
northeaster
Term
lyme disease tx
Definition
early = doxycycline
late = ceftriaxone
Term
1' syphillis
Definition
painless chancre
Term
2' syphillis
Definition
maculopapular rach, condylomata lata
Term
3' syphillis
Definition
gummas, aortitis (vasa vasorum), neurosyphilis (tabes dorsales), argyll robertson pupil
Term
signs of 3' syphillis
Definition
broad based ataxia, positive rhomberg, charcot joint, stroke w/o HTN
Term
syphilis
- screen
- confirm
Definition
- VRDL
- FTA-ABS
Term
congenital syphillis
Definition
saber shins, saddle nose, CN VIII deafness, Hutchinson's teeth, mulberry molars
Term
syphillis tx
Definition
penicillin C (doxycycline if allergic)
Term
argyll roberson pupil
Definition
constricts with accommodation but not to light
Term
fase positie VRDL
- mechanism
- causes
Definition
- ab that reacts with beef cardiolipin
- viruses, drugs, rheumatic fever, lupus and leprosy
Term
cat scratch
Definition
bartonella
Term
ixodes tick
Definition
borrelia burgdorferi
Term
louse
Definition
borrelia recurrentis, epidemic typhus
Term
recurrent fevers
Definition
borrelia recurrentis
Term
parrots
Definition
C psittaci
Term
tick feces and cattle placenta
Definition
C burnetti = Q fever
Term
lone star tick
Definition
e. chaffeensis
Term
ticks, rabbits, deer fly
Definition
f tularensis
Term
armadillos
Definition
m leprae
Term
animal bite (cats, dogs)
Definition
pasteurella mitocida
Term
cellulitis, osteomyelitis zoonotic
Definition
pasteurella
Term
epidemic typhus
Definition
R prowazekii
Term
endemic typhus
Definition
r typhus
Term
dermacentor tick bite
Definition
r rickettsii
Term
flea
Definition
R typus, Y pestis
Term
rodents, prairie dogs
Definition
Y pestis
Term
fishy vaginal discharge
Definition
gardnerella vaginalis
Term
clue cells
Definition
gardnerella vaginalis
Term
gardnerella tx
Definition
metronidazole
Term
rash on hands and feet
Definition
rickettsia, coxsachie A, 2' syphillis
Term
granulocytes with berry cluster organisms
Definition
ehrlichiosis
Term
rickettsia tx
Definition
doxycycline
Term
positive weil-felix
Definition
antirickettsial Ab cross react to proteus O ag
Term
rickettsia with neg Weil-felix
Definition
C burnetti
Term
RMSF location
Definition
east coast
Term
2 forms of chlamydiae
Definition
elementary body = infectious, enters via endocytosis
- reticulate body = replicates in cell
Term
chlamydia causeing atypical pneumonia
Definition
C pneumoniae and C psittaci
Term
chlamydiae tx
Definition
azithromycin, doxycycline
Term
cytoplasmic inclusions on giemsa
Definition
chlamydiae
Term
chlamydiae serotype: blindness
Definition
A B and C
Term
chlamydiae serotype: urethritis/PID
Definition
D-K
Term
chlamydiae serotype: ectopic pregnancy
Definition
D-K
Term
chlamydiae serotype: neonatal pneumonia
Definition
D-K
Term
chlamydiae serotype: neonatal conjunctivitis
Definition
D-K
Term
chlamydiae serotype: lymphogranuloma venereum
Definition
L1-L3
Term
HA, nonproductive cough, diffuse interstitial infiltrate
Definition
m pneumo
Term
with cold agglutinins
Definition
m pneumo
Term
m pneumo tx
Definition
tetracycline or erythromycin
Term
only bacterial membrane containing cholesterol
Definition
mycoplasma
Term
military recruits and prisons
Definition
m pneumo
Term
oral/facial abscesses that drain through sinus tracts
Definition
actinomyces
Term
pulmonary infection in IS patients, weakly acid fast
Definition
nocardia
Term
ghon focus
Definition
Ca scar, lower lobes, 1' TB
Term
ghon complex
Definition
Ghon focus + hilar LAD
Term
4 sequelae of 1' TB
Definition
1= heals by fibrosis -> + PPD
2 = progressive lung dx (HIV, malnutrition)
3 = severe bactermia (miliary TB)
4 = hematogenous dissemination -> dorment tubercle in organs -> reactivation
Term
2' TB
Definition
caseous cavitary lesion in upper lobes
Term
extrapulmonary TB locations
Definition
CNS, vertebral body (Pott's), lymphadenitis, real, GI
Term
PPD+
Definition
current infection, past exposure or BCG vaccination
Term
PPD-
Definition
no infection, steroids, malnutrition, IS, sarcoidosis
Term
mycobacteria: pulmonary symptoms in COPD pts
Definition
M kansasii
Term
mycobacteria: disseminate dx in AIDS
Definition
m avium-intracellulare
Term
mycobacteria: infects skin and superficial nerves
Definition
M leprae
Term
mycobacteria: cervical lymphadenitis
Definition
M scrofulaceum
Term
mycobacteria: aquatic skin lesions
Definition
M marinum
Term
M leprae tx
Definition
rifampin, clofazimine and dapsone
Term
Hansen's: lepromatous vs tuberculoid
Definition
lepromatous = diffuse over skin, communicable, Th2
tuberculoid= few hypo esthetic skin plaques; Th1
Term
dapsone toxicity
Definition
hemolysis and methemoglobinemia
Term
M avium prophylaxis
Definition
azithromycin
Term
gram negative cocci
Definition
Maltose fermenter = N meningiditis
maltose nonfermenter = N gonorrhea
Term
gram negative coccoid rods
Definition
H influenzae, pasteurella, brucella, b pertussis
Term
fast lactose fermenter gram neg rods
Definition
klebsiella, e coli, enterobacter
Term
slow lactose fermenter gram neg rods
Definition
citrobacter, serratia
Term
non lactose fermenter oxidase positive gram neg rod
Definition
pseudomonas
Term
lactose nonfermenter oxidase neg gram neg rod
Definition
shigella, salmonella, proteus
Term
what makes the pink color on MacConkey's?
Definition
they produce beta-galactosidase which breaks down lactose into glucose and galactose
Term
N meningiditis v s gonorrhea: capsule
Definition
meningiditis
Term
N meningiditis v s gonorrhea: maltose fermentation
Definition
meningiditis
Term
N meningiditis v s gonorrhea: vaccine
Definition
meningiditis
Term
N meningiditis v s gonorrhea: STD
Definition
gonorrhea
Term
N meningiditis v s gonorrhea: rifampin prophylaxis
Definition
meningiditis
Term
N meningiditis v s gonorrhea: tx with ceftriaxone
Definition
both
Term
N meningiditis v s gonorrhea: treatment with penicillin G
Definition
meningiditis
Term
diseases with H influenzae
Definition
epiglottitis, meningitis, otitis media, and pneumonia
Term
produces IgA protease
Definition
H influenzae and S pneumo
Term
pontiac fever
Definition
legionella pneuophila
Term
treatment of legionella
Definition
erythromycin
Term
diseases with pseudomonas
Definition
pneumonia, sepsis, external otitis, UTI, drug use and diabetic osteomyelitis
Term
treatment of pseudomonas
Definition
AG plus extended spectrum penicillins
Term
h pylori associated with increased risk for
Definition
peptic ulcer, gastric adenocarcinoma and lymphoma
Term
triple treatment for H pylori
Definition
PPI clarithromycin, and amoxicillin (or metro)
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