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Microbiology
Final Exam part 5
35
Biology
Undergraduate 2
05/06/2011

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Term
interstitial fluid
Definition
Fluid leaving the capillaries
Term
bacteremia
Definition
A few bacteria in blood is OK
Term
Viremia
Definition
presence of viruses in blood
Term
Septicemia
Definition
growth of bacteria in the blood
Term
What is the etiology for septicemia?
Definition
Often nosocomial, arises from another infection often a gram negative problem.
Term
What will septicemia lead to if untreated?
Definition
Leads to shock( collapse of BP, multiorgan failure, lung fill with fluid) and death
Term
What is treatment for septicemia?
Definition
long term low dose antibiotics, support care;high doses may kill the patient due to endotoxin release.
Term
What is the etiology of Tularemia, 'rabbit fever'?
Definition
Francisella tularensis, an aerobic gram ne. rod
Term
What is the transmission for Tularemia?
Definition
direct contact with animals; vecotr by ticks, airborne alse (BW agent)
Term
How does tularemia proceed?
Definition
Skin infection->lymphatic system->lymph nodes->further spread. grows in macrophages.
Term
What is the treatment for Tularemia and what will happen if left untreated?
Definition
tetracycline, 10% mortality if untreated
Term
What is the etiology for Anthrax?
Definition
Bacillus anthracis
Term
What does Anthrax yield?
Definition
a fatal gram pos. septicemia in grazing animals nd humans. YOU will die if it enters bloodstreem.
Term
Modes of transmiss of anthrax
Definition
-Airborne-inhalation of spores (woolsorter's disease)
-Common vehicle-GI anthrax consuming meat from infected animals
Term
What is the treatment for anthrax?
Definition
penicillins
Term
What is the etiology of Lyme disease?
Definition
Borrelia burgdorferi, a spirochete
Term
How is lyme disease transmitted?
Definition
Vecotr transmission, spread by deer ticks
Term
Wahat type of occurance does lyme disease posses?
Definition
seasonal, summer. No person to person transmission
Term
What does the progression of lyme disease mirror?
Definition
Syphilis, another spirochete disease
Term
Primary stage of lyme disease?
Definition
bull's eye rash at site of tick bite, only in 75% of cases.
Term
Seconndary Stage of lyme diseae?
Definition
systematic aches, fever irregular heartbeat, neurological symptoms.
Term
Tertiary stage of lyme diseae?
Definition
months, years later; CMI response yielding crippling arthritis
Term
What is the treatment for lyme diseae?
Definition
tetracyclines
Term
What is the etiology of Rocky Mountain Spotted Fever and where is it endemic to?
Definition
Rickettsi ricketsii, North America
Term
How is rocky mountain spotted fever spread?
Definition
vector transmission.
Term
How does rocky mountain spotted fever effect humans?
Definition
grow in blood veddels yields systemic damge, rash's and in 1% mortality due to heart and kidney damage, if left untrreated
Term
What is the treatment for rockey mountain spotted fever?
Definition
tetracycline
Term
What is the etiology for mononucleosis?
Definition
Epstein Barr Virus, a herpes virus infecting B-celss. shed in saliva
Term
How does mononucleosis effect humans?
Definition
month long incubation, sore throat, fever, spread to lymph, rest of disease takes months, altered B cells produce random Ig
Term
What is the etiology of yellow fever?
Definition
arbovirus
Term
What is the treatment for yellow fever?
Definition
No treatment, only vaccine.
Term
Historic impact of Yellow fever
Definition
helped build panama canal, Walter Reed and colleagues determined relationship with mosquitos
Term
What is the etiology of malaria?
Definition
Plasmodium, a protozoan
Term
What is the life cycle of Malaria-Plasmodium?
Definition
-Sporozoites-live in mosquito, enter blood and germinate in liver cells.
-Merozoites-grow in human host, gro in RBCs, when a RBC bursts fever is triggered.
-Ringed trophozoites- merozoite orecursers in RBCs
Term
What is treatmet for malaria?
Definition
quuinine/chloroquine (block DNA rep.)
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