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Microbiology Lecture 3 Vocab
Macromolecules
29
Biology
Undergraduate 2
01/17/2009

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Term

Dehydration Synthesis

 

(Condensation)

Definition
Chemical reaction in which H2O is removed with the result that two molecules are joined together.
Term
Hydrolysis
Definition
Chemical reaction in which a molecule is broken down as H2O is added
Term

Amino Acid Side Chain

 

(R-Group)

Definition

The variant group in the amino acid that determines its properties:

 

Polar

Nonpolar

Aromatic

Negatively Charged

Positively Charged

Term
Glycine R-Group
Definition
H
Term
Cysteine R-Group
Definition

CH2-SH

 

Can make disulfide bonds

Term
Chiral Carbon
Definition

Has four different groups attached to the carbon

Term
Stereoisomer
Definition
Mirror image of a compound, but cannot superimpose
Term
Peptide Bond
Definition
Covalent bond formed between the -COOH group of one amino acid and the -NH2 group of another amino acid; characteristic of proteins
Term
Beta (Pleated) Sheet
Definition

Secondary structure of a protein that is held together by hydrogen bonding with other amino acids.

 

In the shape of a sheet, referred to as pleated because it can look like its been scrunched up.

Term
Alpha Helix
Definition

Secondary structure of a protein held together by hydrogen bonding

 

In the shape of a helix

Term
Protein Structure
Definition

Primary

 

Secondary

 

Tertiary

Term
Primary Structure
Definition

Refers to the sequence of amino acids in a protein

 

Determines the other features of the protein

Term
Secondary Structure
Definition

Refers to the arrangement of amino acids in a protein; the two major arrangements are helices and sheets

 

Form weak bonds including hydrogen bonds with other amino acids

 

 

Term
Tertiary Structure
Definition

Level of structure of a protein described by its 3D nature; two major shapes exist, globular and fibrous

 

Protein is folded into its 3D shape which is determined by the sequence of amino acids and weak and strong bonds

 

Hydrophobic interactions, hydrogen bonding, disulfide bonds, ionic bond (salt bridge)

Term
Alpha Glycosidic Bond
Definition

Covalent chemical bond that joins two simple sugars, or monosaccharides, via an oxygen atom

 

The OH group points down

 

Animals are able to digest this kind of bond

Term
Beta Glycosidic Bond
Definition

Covalent chemical bond that joins two simple sugars, or monosaccharides, via an oxygen atom

 

OH group points up

 

Bacteria can digest this kind of bond

Term
Nucleotides
Definition

Basic subunits of RNA and DNA consisting of a purine or pyrimidine convalently bonded to ribose or deoxyribose, which is covalently bonded to a phosphate molecule

 

A,T,U,G,C

Term
Purine
Definition
Component of RNA and DNA; the two major purines are adenine (A) and guanine (G)
Term
Pyrimidine
Definition
Component of RNA and DNA; the three major pyrimidines are thymidine (T), cytosine (C), and uracil (U)
Term
5' Phosphate
Definition

Five carbon sugar attached to a phosphate group (PO42-)

 

Phosphate is on the 5th numbered carbon

Term
3' Hydroxyl
Definition
The -OH group is attached to the 3rd numbered carbon on the sugar
Term
Antiparallel Double Helix
Definition
Term used to describe the opposing orientations of the two strands of DNA in the double helix; one strand is oriented in the 5' to 3' direction and its complement is oriented in the 3' to 5' direction
Term
Triglycercide
Definition
Molecule consisting of three molcules of the same or different fatty acids bonded to glycerol
Term
Saturated Fatty Acid
Definition

Contains no double bonds

 

Straight chain

 

All four bonds on carbon are bonded to something

 

Packs very tightly

 

Like butter

 

Animals, plants (wax), bacteria produce naturally

Term
Cis-Unsaturated
Definition

Contains a double bond in the chain

 

The hydrogens are on the same side

 

Very bent and do not pack well, loose, runny

 

Like oil

 

Bacteria produce naturally

Term
Trans-Unsaturated
Definition

Contains a double bond in the chain

 

Hydrogens are on opposite sides

 

Slightly bent (diagonal)

 

Pack decently

 

Like margin

 

Plants (oils) and bacteria naturally produce

Term
Phospholipid
Definition

Lipid that has a phosphate molecule as part of its structure

 

Amphipathic

 

Phosphate head (hydrophilic)

 

Lipid tail (hydrophobic)

Term
Lipid Raft
Definition
Specialized membrane domains enriched in certain lipids, cholesterol, and proteins
Term
Biological Membrane
Definition

Phospholipid Bilayer

 

Has many proteins and lipid rafts (half lipids and half proteins)

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