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Microbiology Lecture 36 Vocab
Leftover Diseases
29
Biology
Undergraduate 2
04/21/2009

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Term
Undulant Fever
Definition

Caused by Brucellosis, a major ungulate pathogen (in goats, sheep, and cattle)

 

It causes chills and fever, alternating daily for months

Term
Cattle Abortion "Storms"
Definition

Brucellosis can be transmitted via the placenta and testes

 

Through the testes it can be transmitted via semen from wild to domestic or via pasture contamination from the placenta making it spread quickly throughout the herd when they eat the grass

 

Term
Canine Brucellosis
Definition

The dog version of Brucellosis

 

10% of strays infected

 

It can take out an entire kennel

Term
Graulomatosis Infantispetica
Definition
When Listeria monocytogenes infects the placenta causing a stillbirth
Term
Acetylcholine
Definition
The neurotransmitter that signals muscle contraction
Term
Infant Botulism
Definition

Botulism prevents ACh release causing flaccid muscle paralysis

 

The infant kind is refered to as "Floppy Baby"

 

They get it from honey (Clostridium botulinum can stay on the can if it isn't sterilized properly) because they don't have any native flora to fight off the bacteria

Term
Wound Botulism
Definition

Botulism caused by drug injection

 

Botulism caused by Clostridium botulinum

 

Like the "Botox" parties (fine in low concentrations, but can be deadly if it isn't just right)

Term
"botox" = botulin toxin
Definition
Toxin that causes flaccind muscle paralysis from Clostridium botulinum
Term
Epstein-Bar Virus
Definition

Virus that causes mono

 

Transmitted via saliva

 

In the herpesvirus family

Term
Heterophile Antibody Test = MonoSpot Test
Definition

The test for mono

 

Tests for random antibodies produced by the body

 

See if the patient's serum agglutinates ox RBCs (a random animal antigen)

Term
Encephalitis
Definition

Inflammation of the brain

 

Most the cases are transmitted via mosquito bites (can't spread human to human)

 

Caused by flavivirus (St. Louis and W. Nile encephalitis)

Term
"Dead End" Host
Definition

When a host gets infected with a virus, but because it has low levels of viremia it cannot be transmitted to other hosts of the same species

 

Like West Nile where it can be transferred to humans through mosquites, but humans cannot spread it to one another

Term
Retrograde Axonal Transport
Definition

This is what Rabes does

 

The virus replicates most rapidly in the CNS so they get there via axonal transport in the opposite direction (Axon --> Cell Body)

Term
Anterograde Axonal Transport
Definition

This happens in rabies

 

When the virus is able to replicate in the CNS it can spread via this mechanism to the salivary glands and cornea

Term
Rabies Immune Globin
Definition

Often this IgG is given passively to patients infected with rabes in addition to the vaccine

 

(The vaccine works after exposure because it can take a long time before the virus replicates and causes problems)

Term
Negri Bodies
Definition

This is what the rabes virus, rhabdovirus, produces in the CNS

 

A characteristic of rabies

Term
Plasmodium
Definition

The causative agent of Malaria

 

It is a sporozoan

 

There are 4 species of this

Term
Sporozoite
Definition
This is what infects humans from mosquitos to cause malaria
Term
Merozoite
Definition
When the sporozoite migrates to liver and the liver cells produces merozoites by schizogony
Term
Ring form
Definition

This the first thing that is produced when the merozoites infect RBCs

 

Involved with Malaria

Term
Trophozoites
Definition

This is what forms after the ring forms form in the RBC

 

For Malaria

Term
Schizont
Definition

This is what forms after the trophozoite forms in the RBC (will form merozoite again, so it can enter new RBCs and lyse them)

 

Associated with Malaria

Term
Gametocyte
Definition
After merozoites from the liver enter the RBC they will then enter this
Term
Zygote
Definition

When the gametes of the mosquitos come together and form this

 

In gut wall

Term
ookinate
Definition

The next thing the zygote of the mosquito develops into

 

In gut wall

Term
Oocyst
Definition

The next thing the ookinate develops into

 

In mosquitos/Malaria

 

In gut wall

Term
Quinine/ Chloroquine/ Primoquine
Definition
The drugs used to try to treat Malaria, but none of them kill the early ring cells
Term
artemisinin combined therapy (ACT)
Definition

A treatment used to kill early ring cells for Malaria

 

Costly treatment

Term
RTS,S Vaccine
Definition
The developing vaccine for Malaria
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