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Microbiology Lecture 11 Vocab
Use and Synthesis of Carbon Compounds
24
Biology
Undergraduate 2
02/07/2009

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Term
Anabolism
Definition

Cellular processes that use the energy stored in ATP to synthesize and assemble subunits such as amino acids; synonymous with biosynthesis

 

"Builds Up"

Term
Catabolism
Definition

Celluar processes that harvests the energy released during the breakdown of compounds such as glucose and use that energy to synthesize ATP

 

"Breaks Down"

Term
Oxidation
Definition
Loosing Electrons
Term
Reduction
Definition
Gaining Electrons
Term
Reducing Power
Definition

Reduced electron carriers such as NADH, NADPH, and  FADH2; their bonds contain a form of useable energy

 

 

Term
Enzyme
Definition
A protein that functions as a catalyst
Term
Active Site
Definition
Where the substrate(s) binds to the enzyme
Term
Induced Fit
Definition
When the enzyme folds around the substrate and takes the shape of it to hold on to it during the catalyzed reaction
Term
Competitive Inhibitor
Definition
When the inhibitor for the enzyme competes with the normal substrate for binding to the active site.
Term
Noncompetitive (Allosteric) Inhibitor
Definition

When the inhibitor interacts with another part of the enzyme to cause a shape change at the active site for the substrate

 

Doesn't resemble the substrate

Term
Central Catabolism
Definition
Glycolysis, the TCA cycle, and pyruvate oxidation
Term
Glycolysis
Definition

Metabolic pathway that oxidizes glucose to pyruvate, generating ATP and reducing power

 

Oxidizes glucose and produces ATP, pyruvate, and NADH (electrons, by reducing NAD)

Term
Oxidative Decarboxylation of Pyruvate
Definition
When the electrons in pyruvate are transferred to NAD to make NADH and pyruvate releases CO2
Term
Electron Carrier (NAD/NADH)
Definition
NAD gets reduced by accepting electrons to make NADH in glycolysis, oxidatively decarboxylated pyruvate, and TCA cycle
Term
Acetyl CoA
Definition

Product of the transition reaction; a precursor metabolite used in fatty acid synthesis

 

Oxidized during the TCA cycle

Term
TCA (Krebs', Citric Acid) Cycle
Definition
 Metabolic pathway that incorporates acetyl-CoA, ultimately generating CO2, reducing power, ATP, and NADH and FADH2
Term
Fermentation
Definition

Metabolic process in which the final electron acceptor is an organic compound

 

No O2

Term
Dehydrogenase?
Definition
Enzyme that helps in the oxidation reaction in which both an electron and an accompanying proton are removed
Term
Electron Acceptor
Definition
A molecule that gets reduced or accepts electrons
Term
pentose phosphate pathway
Definition
Metabolic pathway that initiates the degradation of glucose, generating reducing power in the form of NADPH, and two precursor metabolites
Term
respiratory electron transport chain
Definition
When the final electron acceptor is an inorganic compounds like oxygen
Term

epimerases / isomerases

Definition
An enzyme that catalyzes the structural rearrangement of isomers
Term
beta-oxidation
Definition
The process by which fatty acids, in the form of Acyl-CoA molecules, are broken down in mitochondria and/or in peroxisomes to generate Acetyl-CoA, the entry molecule for the Krebs cycle
Term

deamination

Definition

The removal of an amine group, usually by hydrolysis

 

Used for the hydrocarbon skeleton for energy

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