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microbiology - antimicrobe
antimicrobial drugs
24
Biology
Undergraduate 1
12/09/2009

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Term
primaxin
Definition
broad spectrum Carbepenums
Term
aztreonam
Definition
single ring B-lactam
one of Monobactams
Term
cephlosporins
Definition
class of drug. inhibits cell wall synth. Various generations with newer having broader spectrum.
Term
Prontosil dye
Definition
first sulfanimide
Term
Salvarsan
Definition
Erlich's magic bullet. first antimicrobial
Term
streptomycin
Definition
Selman Waksman isolated streptomycin from soil bacterium Streptomyces griseus
Term
Niclosamide
Definition
Prevents ATP generation
Tapeworms
Term
Praziquantel
Definition
Alters membrane permeability
Flatworms
Term
Mebendazole
Definition
Inhibits nutrient absorption
Intestinal roundworms
Term
Chloroquine
Definition
Inhibits DNA synthesis
Malaria
Antiprotozoan Drugs
Term
Diiodohydroxyquin
Definition
Unknown mode of action
Amoebic diseases
Antiprotozoan Drugs
Term
Metronidazole
Definition
Damages DNA
Entamoeba, Trichomonas
Antiprotozoan Drugs
Term
Nitazoxanide
Definition
Interferes with metabolism of anaerobes
Antiprotozoan Drugs
Term
Polyenes
Definition
very toxic to humans
Limited to use in life-threatening disease; Target for most antifungal medications is ergosterol
Term
amantadine and rimantadine
Definition
Viral uncoating
Antiviral Drugs
Term
foscarnet and acyclovir
Definition
Non-nucleoside polymerase inhibitors
Antiviral Drugs
Term
nevirapine, delavirdine, efavirenz
Definition
Non-nucleoside reverse transcriptase inhibitors
Antiviral Drugs
Term
indinavir and ritonavir
Definition
Protease inhibitors;Antiviral Drugs
Term
zanamivir and oseltamivir
Definition
Neuraminidase inhibitors
Antiviral Drugs
Term
ketolides
Definition
synthetic macrolide
macrolytic lactone ring, inhibits protein synth
Term
quinolone group
Definition
inhibits dna gyrase
good for URI
Term
floroquinolones
Definition
synthetic quinolone including cipro
Term
aminoglycide group
Definition
interfere with protein synth by changing shape of 30s unit
against gram NEG
streptomycin
Term
tetracyclines
Definition
broad spectrum antibiotic group produced by streptomyces
interfere with tRna in protein synth
doxy = semi-syntetic
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