Term
|
Definition
-modified apocrine sweat glands
-ectodermally derived |
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Term
| Mammary gland development |
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Definition
1. mammary ridges develop
2. epidermis proliferates to form primary bud
3. secondary buds form to become lactiferous ducts
*sometimes supernumary nipples occur (polythelia) |
|
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Term
| Breast development in females |
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Definition
-ovarian estrogens
1. accumulation of CT
2. accumulation of fat
3. proliferation of ducts to form lobules |
|
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Term
| Structural organization of breast |
|
Definition
1. 15-20 compound tubuloalveolar glands in 15-20 lobes
2. lobes contain lobules
3. secretory alveoli--simple cuboidal, with myoepithelial cells
4. intralobular ducts--simple cuboidal
3. interlobular ducts--between lobules, simple cuboidal
4. lactiferous duct-stratified cuboidal/columnar
5. lactiferous sinus-stratified squamous |
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Term
|
Definition
-estrogen, progesterone, human chorionic somatomammotropin, and prolactin are released
-simple columnar epithelium of alveoli become low cuboidal as milk production increases |
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Term
|
Definition
-lipids secreted by apocrine secretion
-proteins secreted by merocrine secretion |
|
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Term
|
Definition
| -high protein secretion with IgA for passive immunity |
|
|
Term
| prolactin inhibitory factor |
|
Definition
-inhibits prolactin
-PIF inhibited by suckling |
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Term
|
Definition
|
|
Term
| Regression of mammary gland |
|
Definition
|
|
Term
| Involution of mammary gland |
|
Definition
-occurs after menopause
-less glandular, fat tissue |
|
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Term
|
Definition
-common for women between 30 and 50
-fluid filled cysts if ducts get blocked off |
|
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Term
|
Definition
-male breast disorder
-common among pubescent boys
-hormone imbalance |
|
|
Term
|
Definition
1. DCIS-confined to ducts
2. Infiltrating DC-invaded fatty tissue of breast (80% of cases)
3. infiltrating lobular CA-starts in milk glands |
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