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MICRO
CH2020
74
Microbiology
Undergraduate 1
06/24/2013

Additional Microbiology Flashcards

 


 

Cards

Term
What are characteristics of pathogenic strains of Neisseria that are useful for identifying them in the laboratory?
Definition
diplococcus with oxidase enzyme activity and fastidious growth requirements
Term
Lipid A causes what symptoms?
Definition
fever and disseminated intravascular coagulation (DIC)
Term
Neisseria is
Definition
the only genus of Gram-negative cocci that regularly causes disease in humans
Term
What is TRUE about Neisseria gonorrhoeae?
Definition

infected woman are often asymptomatic;

the gonococci stick to epithelial cells via fimbriae and capsules;

it causes disease in humans only;

the gonococci secrete a protease that destroys secretory IgA.

Term
Among the areas of the female genital tract, what is NEVER infected with Neisseria gonorrheae?
Definition
the vagina
Term
The major damage caused by Neisseria meningitidis is a result of?
Definition
the release of the Lipid A component of lipooligosaccharide(LOS) into the tissues, triggering serious symptoms.
Term
what is a diagnostic for Neisseria meningitidis?
Definition
the presence of Gram-Negative diplococci in phagocytes of the CNS
Term
Members of the Enterobacteriaceae can be distinguished from each other by?
Definition
motility and the ability to ferment lactose
Term
What virulence factors do all proteobacteria share?
Definition
Lipid A
Term
What is TRUE about Neisseria meningitidis?
Definition
humans are the only natural carriers, up to 40% of the population ar carriers, it often causes meningitis, transmission is via respiratory droplets.
Term
a lung specimen from a pneumonia patient contains Gram-negative bacilli. Laboratory test results on the bacteria show they are nonmotile coliforms with a capsule. Which pathogen is the likely cause of the pneumonia?
Definition
Klebsiella
Term
What coliform is the most common cause of non-nosocomial UTI's?
Definition
Escherichia coli
Term
Serratia is a coliform that?
Definition
produces red pigment when grown at room temp
Term

which of the following pairs are mismatched?

a)coliform Enterobacteriaceae- rapid lactose fermenters

b)noncoliform opportunistic Enterobacteriaceae- Proteus, Morganella

c)noncoliform Enterobacteriaceae- non-lactose-fermenters

d)nonpathogenic Enterobacteriaceae- Salmonella, Shigella

e)coliform Enterobacteriaceae- opportunistic pathogens

Definition
d)nonpathogenic Enterobacteriaceae- Salmonella, Shigella
Term
Several cases of severe, nonbloody diarrhea with fever and abdominal pain have occurred among a number of people who ate at the same restaurant. Public health officers find a food sample containing noncoliform, nonmotile Gram-negative bacteria capable of metabolizing urea. The "food poisoning" resulted from contamination with?
Definition
Yersinia
Term
Shigellosis can be differentiated from salmonellosis by?
Definition
the presence of nonmotile noncolifroms in bloody diarrhea
Term
what is the causative pathogen for bubonic and pneumonic plague?
Definition
Yersinia pestis
Term
What bacteria requires heme for its growth?
Definition
Haemophilus
Term
a young woman has a pelvic infection. a specimen contains bacilli that are bile salt tolerant, as shown by growth on a bile-esculin agar plate. Her infection is likely caused by?
Definition
Bacteroides fragilis
Term
What is true about Pasteurella?
Definition
it is fastidious in its growth and must be cultivated on blood or chocolate agar, it is nonmotile, it is oxidase positive, and humans are typically infected via animal bites
Term
Cat scratch disease is caused by?
Definition
Bartonella henselae
Term
Bordetella pertussis, the pathogen responsible for whooping cough, causes diseases by?
Definition
interfering with the action of the ciliated epithelial cells of the trachea
Term
Rsistance of Pseudomonas to a wide range of antibacterial agents is partly due to its?
Definition
ability to form biofilms
Term
What disease can be prevented by vaccination?
Definition
typhoid fever
Term
Legionnaires' disease is diagnosed by?
Definition
fluorescent antibody or other serological diagnostic procedures
Term
What is true about Coxiella?
Definition
it prefers an acid environment, it was once thought to be a virus, it produces an infective body similar in structure and function to endospores produced by some Gram- positive species, it is an obligate intracellular parasite that grows within phagolysosomes.
Term
What is FALSE regarding Coxiella?
Definition
it must use its host's ribosomes.
Term
Wh is the causative pathogen of Q fever?
Definition
Coxiella burnetii
Term
How do Prevotella differ from Bacteroides?
Definition
They are sensitive to bile
Term
What toxins produce by Bordetella pertussis results in the accumulation of excess mucus in the trachea?
Definition
pertussis toxin and adenylate cyclase toxin
Term
Hemolytic uremic syndrome is caused by?
Definition
Escherichia coli O157:H7
Term
A cystic fibrosis pt develps a severe respiratory infection that resists treatment with standard ABX. A specimen from the lungs is greenish in color and contains aerobic motile Gram-negative bacilli. The patient is probably infected with?
Definition
Pseudomonas aeruginosa
Term
What is the characteristic lesion of Yersinia pestis?
Definition
a bubo
Term
What is the antimicrobial agent of choice for treating Bacteriodes infections?
Definition
metronidazole
Term
What bacteria was formerly classified in the same family as Neisseria?
Definition
Moraxella
Term
What organism produces concentric wavelike patterns due to swarming cells when it is cultured on agar?
Definition
Proteus
Term
Q fever?
Definition
inhalation of dried bodily fluids of infected animals
Term
UTI with kidney stones?
Definition
Proteus
Term
Meningitis in infants 3-18 months old
Definition
Haemophilus influenzae
Term
Chancroid or soft chancre?
Definition
Haemophilus ducreyi
Term
Abortion in infected goats and sheep, but not in infected humans?
Definition
Brucella
Term
Pelvic inflammatory disease (PID)
Definition
Sexually transmitted
Term
Legionnaires' disease
Definition
inhalation of bacteria in aerosols
Term
Bubonic plague
Definition
the bite of an infected flea
Term
Salmonellosis?
Definition
contamination of food by inoculation from cracking an egg
Term
Trench Fever?
Definition
transmitted by human body lice
Term
T/F Some scientists believe that Shigella may actualy be a strain fo E. coli that has become oxidase positive?
Definition
FALSE
Term
T/F Humans are the sole hosts of Salmonella typhi.
Definition
True
Term
T/F Lipid A causes disseminated intravenous coagulation (DIC)
Definition
TRUE
Term
T/F Enterobacteriaceae are rarely pathogenic.
Definition
FALSE
Term
T/F Gonococcal infections result in lifelong immunity against Neisseria gonorrhoeae?
Definition
FALSE
Term
T/F Intravenous ceftriaxone is the drug of choice for treating meningococcal meningitis?
Definition
TRUE
Term
T/F By controlling the geneticexpression of Vi and H antigens, Salmonella evades the host's immune system and manages to survive..
Definition
TRUE
Term
T/F MacConkey agar is selective for Haemophilus influenzae.
Definition
FALSE
Term
T/F Haemophilus ducreyi is transmitted sexually.
Definition
TRUE
Term
T/F Moraxella is a common cause of bacteremia.
Definition
FALSE
Term
T/F Coxiella burnetii is transmitted to humans mainly via the bite of infected tick vectors.
Definition
FALSE
Term
T/F Neisseria meningitidis is able to survive inside macrophages and be transported throughout the body in them.
Definition
TRUE
Term
Untreated gonorrhea in women can lead to a condition known as ______.
Definition
PID
Term
Neisseria is distinguished from many other Gram-negative pathogens by being ____ positive.
Definition
oxidase
Term
Because of the existence of ______ carriers, the eradication of meningococcal disease is unlikely.
Definition
healthy asymptomatic carriers
Term
Infection with _____ can frequently be diagnosed by the presence of blue-green discoloration of tissues.
Definition
Pseudomonas aeruginosa
Term
The ____ in enteric bacteria allows them to form channels through which bacterial proteins are introduced into the host cell, helping them evade immune surveillance.
Definition
type III secretion system
Term
Antimicrobial therapy in individuals infected with Enterobacteriaceae may worsen the prognosis b/c of the release of large amounts of ______.
Definition
Lipid A
Term
The pleomorphic bacterium ____ is an intracellular parasite that can lead to respiratory disease when inhaled in aerosols from moist environments.
Definition
Legionella
Term
Pneumonia caused by ____ often involves the destruction of alveoli and the production of bloody sputum.
Definition
Klebsiella pneumoniae
Term
Of all the types of Proteus, ______ is the most common species associated with disease in humans.
Definition
P. mirabilis
Term
Scientists have identified over 2000 unique serotypes of Salmonella, but DNA analysis indicates that they belong to a single species: _______.
Definition
S. enterica
Term
________, caused by Yersinia pestis, is not spread from person to person.
Definition
Bubonic plague
Term
____ are gammaproteobacteria that are oxidase positive and require cytochromes or heme as part of their growth requirements.
Definition
Pasteurellaceae
Term
The zoonosis _____ can be acquired by humans in a variety of ways, including inset bites and ingestion of infected animals.
Definition
tularemia
Term
Dermonecrotic toxin is produced by _____ and causes localized constriction and hemorrhage of blood vessels, resulting in cell death and tissue destruction.
Definition
Bordetella pertussis
Term
_____ is a medical puzzle b/c even though it expresses a wide range of virulence factors, it rarely causes disease.
Definition
Pseudomonas aeruginosa
Term
Why is treatment with antimicrobial drugs NOT encouraged in patients with diarrhea caused by enteric bacteria?
Definition
Antimicrobial treament of enteric diarrhea can worsen the prognosis by killing many bacteria at once, releasing large amounts of lipid A. The release of lipid A from these bacteria causes fever, vasodilation, inflammation, shock, and DIC, potentially leading to death. In addition, the diarrhea is normally self-limiting, and the expulsion of the organisms from the body is often more effective than antimicrobial phagocytes.
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