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Micro Test #3
Disease
27
Biology
Undergraduate 2
11/11/2008

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Term
Period of Acute disease
Definition
1. Incubation- time from infection to symptoms
2. Prodromal- feel symptoms
3. Acute= invasion, signs & symptoms
4. convalescent- getting better
Term
Persistent Infection
Definition
1. Chronic- low level, long time
2. latent- symptoms go away and come back
3. slow- infected, takes long time for symptoms to arrive
Term
Virulence Factors of S. Aureus
Definition
Hemolyosins
Toxins
Enzymes
Protein A
Term
Toxins associated with Staph
Definition
1. Leukocidin- kills leukocytes (PMNs)
2. Enterotoxin- food posioning
3. TSS
4. Exfoliatin- scaled skin syndrome
Term
Enzymes Associated with Staph
Definition
1. Coagulase- blocks opsoninzation
2. Fibrinolysin- breaks down fibrin
3. DNAse
4. Hyalurondiase- breaks CT
5. Penicillinase- resistant to antibiotcis
Term
S aureus disease ( general)
Definition
1. Skin Infections
2. Deep Infections
3. Food Poisioning
Term
S aureus skin infections
Definition
1. folliculitis
2. furncles
3. carbuncles
4. impetigo
5. scalded skin syndrome
Term
S aureus deep infections
Definition
1. Pneumonia
2. septicemia
3. osteomylitus
4. TSS
5. Enterocolitis
Term
Facultatively anaerobic strep
Definition
1. pyogenic
2. viridans
3. enterococcus
4. pneumocci
Term
Microaerophilis strep
Definition
S mutans --> cause cavities
Term
Obligate Anaerobic Strep
Definition
Peptostreptococcus
peptococcus
Term
Pyogenic strep
Definition
beta, pus forming
S pyogenes- group A- throat, most common
S agalactiae- group B- vagina
Term
Viridans ( strep)
Definition
alpha
s angius- oral mucosa
Term
Enterococcus (strep)
&
Pneumococci
Definition
group d- in the GI tract

normal oral and nasopharyngeal microflora
Term
Virulence Factors of Beta Strep
Definition
1. M Protein (coagulase)
2. hemolysins- RF
3. fibrinolysin
4. DNAse
5. Erythogenic exotosin
6. Hyaluronidase-
7. cardiohepatic toxin
8. nephrotoxin
9. protein F
Term
Infections of Strep
Beta hemolytic: S pyogenes, S agalactiae
Definition
1. pharyngitis- strep throat
2. Impetigo- ersipelas
3. scarlet fever
4. neotnatal infection- from vagina
5. INFECTIVE endocarditis
Term
Strep= S. angius infection
Definition
ineffective endocarditis- subacute
Term
Post- strep
Definition
1. Rheumatic Fever- gp A infection- autoimmune
2. acute glomerulonephritis- skin infection
Term
Bacillus anthrax/ gastroenteritis
Definition
* biological monitors = evaluate sterile equipment*
disease of cattle
cause skin infections- black scab

food poisoning
Term
Corynebacterium
Definition
does not form spores, obligate anaerobes
Term
C- diphtheria = the toxin
Definition
must produce the toxin to form a disease
dependent on bacteriophage
localized in the oropharynx
pseudo membrane formation in throat- gree
death by hear failure
vaccine= DPT
Term
Clostridium
Definition
does not form spores
anaerobic- does not need oxygen--> they lack the enzymes superoxide and catalase- which gets rid of toxic byproducts of oxygen
Term
Clostridial Diseases
Definition
1. Botulism
2. tetanus
3. Gas gangrene
4. pseudo membranous colitis ( C DIF)
Term
Botulism
Definition
( Clostridium)
food poisoning associated with canned foods- affects peripheral nerves

treat with anit-toxin

DEATH beacuse of respiratory failure
Term
Tetanus
Definition
( clostridium)
produces neurotoxin- aka LOCKJAW
causes paralysis of muscles- cleanched "grin"
Term
Gas Gangrene
Definition
tissue liquidizes ( bc of collagenase)
death due to toxemia
Term
Myobacterium Tuberculosis
Definition
spread via droplet nuclei (sneeze, cough), or contaminated particles( milk)
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