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micro quiz 4/24
n/a
45
Biology
Undergraduate 3
04/24/2009

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Term
major ungulate pathogen (goats, sheep, cattle) that rarely infects humans since milk pasturization laws
Definition
brucellosis
Term
brucellosis symptoms
Definition
chills, fever daily for months, granuloma formation
Term
brucellosis symptoms in animals
Definition
abortion storms - bacterium binds to erythritol in the placenta and testes -- kills hundreds of babies
Term
brucellosis eradication
Definition
live attenuated vaccine added to hay
Term
dangerous foodborne pathogen found in soft cheeses and hot dogs
Definition
listeria monocytogenes
Term
oxygen requirement for listeria and the importance of it
Definition
facultative psychrophile - can grow in the fridge
Term
symptoms of listeria
Definition
nonspecific GI symptoms, meningitis in old and immunocompromised, infects placenta causing still birth (granulomas) or infant meningitis
Term
botulism bacteria
Definition
clostridium botulinum
Term
botulism poisoning
Definition
caused by very potent AB toxin, B part binds to neuromuscular junction, A part is a peptidase that prevents acetylcholine release = muscles cant contract
Term
botulism symptoms
Definition
foodborne, intestinal symptoms, floppy baby
Term
why isn't botulism common in the US anymore
Definition
canning procedures keeps it out of food
Term
why shouldn't you give babies honey until they're a year old?
Definition
floppy baby caused by botulism - no native flora to protect against it (i guess botulism is common in honey?)
Term
Disease caused by the epstein-barr virus and what family is that in?
Definition
mono - herpes family
Term
How is mono transmitted?
Definition
saliva
Term
symptoms of mono
Definition
very long incubation period, infects throat epithelium causing pharyngitis with pus, lymph node swelling, occasionally spleen rupture
Term
How does the monospot test work?
Definition
mono infects B cells and causes them to proliferate to produce heterophile antibodies, the monospot test sees if the pt. serum agglutinates ox RBCs (bc we shouldn't have antibodies against these, but will if we have heterophile antibodies)
Term
heterophile antibodies
Definition
random antibodies, not against the virus infecting the person
Term
Why does mono make you so tired?
Definition
Lymphocytes proliferate with cytokine signal from t cells - takes a lot of energy
Term
fate of b cells after infection by epstein-barr virus
Definition
either because latent or are infected and proliferate
Term
encephalitis viruses are most often transmitted by?
Definition
mosquitos
Term
Eastern and Western Equine Encephalitis are what kind of viruses?
Definition
togaviruses
Term
St. Louis and West Nile encephalitis are what kind of viruses?
Definition
flaviviruse
Term
Lacrosse Encephalitis is what kind of virus?
Definition
bunyavirus
Term
Most kinds of encephalitis are spread in what animal?
Definition
birds
Term
___ are a dead end host for encephalitis. meaning?
Definition
humans - cant be transmitted FROM humans
Term
encephalitis symptoms
Definition
crosses blood-brain barrier and causes extensive damage, death, or permanent disability
Term
Bullet-shaped rhabdovirus causes what disease
Definition
rabies
Term
rabies is endemic in?
Definition
mammals - transmitted to humans through their saliva
Term
Rabies proliferation and detection
Definition
travels in axon to CNS and replicates there, takes months or years, produces Negri bodies (protein aggregate), anterograde transport to salivary glands... detected by corneal smear
Term
Why can the rabies vaccine be given AFTER the bite?
Definition
because retrograde transport takes so long that the patient has time to build up antibodies
Term
rabies treatment
Definition
vaccine and passive IgG (RIG)
Term
life cycle of rabies virus
Definition
neuron, anterograde (orthograde transport), replication in cell, enters saliva, transmission to new host, retrograde axonal transport, starts over
Term
__ infects about 10% of the world's population, causing a death about every 30 sec
Definition
malaria
Term
malaria is transmitted by?
Definition
mosquitos (anopheles)
Term
malaria causative agent
Definition
sporozoan (plasmodium)
Term
___ causes the most serius malaria.. can effect brain causing cerebral malaria
Definition
p. falciparum
Term
producer
Definition
autotroph - sun (photoautotroph) or oxidation (chemoautotroph)
Term
consumer
Definition
heterotroph
Term
decomposer
Definition
heterotroph specializing in decomposition - release monomers needed by producers to start chain over
Term
oligotrophic bodies of water
Definition
clear water, low productivity - desirable for large fish
Term
mesotrophic bodies of water
Definition
increased production, accumulated organic matter, occasional algal bloom, good fishery
Term
eutrophic bodies of water
Definition
very productive, may experience oxygen depletion, rough fish
Term
bacteriocidins
Definition
produced by microbes in dense culture, kill other microbes, kill same species to reduce overall cell density
Term
quoromones
Definition
communication molecules - regulate gene transcription, biofilm formation, virulence factor production, etc
Term
components of flowing water
Definition
rapid oxygenation, phototrophs, sheathed bacteria adhere to rocks = super biofilm
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