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Micro Exam 1
Lecture 1 (Disease)
20
Other
Not Applicable
06/08/2008

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Term
Stedman's Definition of Disease
Definition
morbus; illness; sickness; and interruption, cessation of disorder of body functions
Term
Disease Criteria
Definition
- a recognized etiologic agent
- an identifiable group of signs and symptoms
- consistent anatomical alterations
Term
Infectious Disease (Stedman's)
Definition
- one resulting from the presence and activity of a microbial agent
Term
Koch's Postulates
Definition
- microbe must be present in every case of the disease
- microbe must be isolated from the diseased host and grown in pure culture
- disease must be reproduced when a pure culture is introduce into a non-diseased susceptible host
- microbe must be recoverable from an experimentally infected host
Term
Prokaryotes
Definition
- bacteria
Term
Eukaryotes
Definition
- fungi
- protozoa
- protists, microscopic worms, arthropods
Term
Indegenous Microbia
Definition
- aka resident, commensal or normal flora
- bacteria, fungi, viruses, protozoans, other protists and and a mite
- occupy all body surfaces and orifices
Term
Parasite
Definition
- life form that lives on or in another life form
Term
Saprophye
Definition
- organism that lives on dead organic matter
- fungi on humans (dead skin)
Term
Pathogen
Definition
- organism that has capacity to cause disease
- true, primary, frank, strict
Term
pathogenicity
Definition
- ability of microorganism to cause disease
Term
Virulence
Definition
- degree of pathogenicity or the likihood of causing disease
Term
Commensal
Definition
- organism that lives on or within another organism from which it derives benefit but neither injures nor benefits
Term
Symbiosis
Definition
- relationship between two or more organisms which is mutually beneficial
Term
Synergistic Bacterial Reaction
Definition
- positive reaction
- produce substances utilized by other species
- ex: lactic acid produced by strep utilized by veillonella on tongue
Term
Antagonistic Bacterian Reaction
Definition
- inhibit other species
Term
Advantages of normal flora
Definition
- preven colonization
- release substances of metabolic value for host
- antigenic stimulation important to normal development of immune system
- provides some energy for development
Term
Disadvantages of Normal Flora
Definition
- opportunistic infections occur when bacteria spreads into sterile area
Term
Steps for Infectious Microorganisms
Definition
- attachment/entry
- local/general spread
- multiplication
- evasion of host defenses
- shedding from body/exit
- cause damage to host (not STRICTLY necessary)
Term
Pathogenic properties of Bacteria
Definition
- ability to produce endotoxins
- endotoxin of gram (-) cell wall
adhesions and pili to enhance attachment
- capsules to avoid phagocytosis
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