Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Binds PBPs and enzymes responsible for peptidoglycan synthesis |
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Term
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Definition
Disruption of Cell Wall
Inhibits cross-linkage of peptidoglycan layers |
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Term
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Definition
Disruption of Cell Wall
Causes depolarization of cytoplasmic membrane, resulting in disruption of ionic concentration gradients |
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Term
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Definition
Disruption of Cell Wall
Inhibits bacterial cytoplasmic membrane and movement of peptidoglycan precursors |
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Term
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Definition
Disruption of Cell Wall
Inhibits bacterial membranes |
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Term
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Definition
Disruption of Cell Wall
Inhibits mycolic acid synthesis |
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Term
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Definition
Disruption of Cell Wall
Inhibits mycolic acid synthesis |
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Term
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Definition
Disruption of Cell Wall
Inhibits arabinogalactan synthesis of cell wall |
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Term
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Definition
Disruption of Cell Wall
Inhibits cross-linkage of peptidoglycan layers |
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Term
Amikacin
(aminoglycosides) |
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Definition
Inhibition of Protein Synthesis
Produces premature release of aberrant peptide chains from 30S ribosome |
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Term
Gentamycin
(aminoglycosides) |
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Definition
Inhibition of Protein Synthesis
Produces premature release of aberrant peptide chains from 30S ribosome |
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Term
Tobramycin
(Aminoglycosides) |
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Definition
| Inhibition of Protein Synthesis Produces premature release of aberrant peptide chains from 30S ribosome |
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Term
Tetracyclines
(doxycyline and monocycline) |
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Definition
Inhibition of Protein Synthesis
Prevents polypeptide elongation at 30S ribosome |
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Term
Tigecycline
(Glycylcyclines) |
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Definition
Inhibition of Protein Synthesis
Binds to 30S ribosome and prevents initiation of protein synthesis |
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Term
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Definition
Inhibition of Protein Synthesis
Prevents initiation of protein synthesis at 50S ribosome |
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Term
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Definition
Inhibition of Protein Synthesis
Prevents initiation of protein synthesis at 50S ribosome via 23S rRNA |
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Term
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Definition
Inhibition of Protein Synthesis
Prevents initiation of protein synthesis at 50S ribosome via 23S rRNA |
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Term
|
Definition
Inhibition of Protein Synthesis
Prevents initiation of protein synthesis at 50S ribosome via 23S rRNA |
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Term
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Definition
Inhibition of Protein Synthesis
Prevents polypeptide elongation at 50S ribosome |
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Term
Quinolones
(fluoroquinolones and nalidixic acid) |
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Definition
Inhibition of DNA Synthesis
Targets DNA gyrase-A in gram -ve
Targets Topoisomerase Type IV in gram +ve |
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Term
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Definition
Inhibition of DNA Synthesis
Disrupt DNA via bacterial NITROreductase |
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Term
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Definition
Inhibition of DNA Synthesis
Inhibit LEPROSY DNA |
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Term
Rifampin and Rifabutin
(derivatives of Rifamycin B) |
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Definition
Inhibition of RNA Synthesis
Binds to DNA-dependent RNA polymerase and inhibit RNA synthesis |
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Term
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Definition
Antimetabolites
Inhibits dihydropteroate synthase
Inhibit dihydrofolate reductase
Prevent conversion of dihydrofolate to tetrahydrofolate
Disrupts folic acid synthesis |
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Term
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Definition
Antimetabolites
Inhibits dihydropteroate synthase via competing with p-aminobenzoic acid and prevent folic acid synthesis |
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Term
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Definition
Antimetabolites
Antifolates for mycobacteria |
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Term
| Para-aminosalicyclic acid |
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Definition
Antimetabolites
Antifolates for mycobacteria |
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