Term
| What is crystal Methamphetamine? |
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Definition
| A chemical stimulant that is highly addictive and causes pts to become dangerous while under influence. |
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Term
| What are the effects in time of Meth after taking? |
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Definition
oral: 20-30m snort 3-5m smoke: 7-10 skin bumps: 10-15 effects last. |
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Term
| What is unique about the geographical spread of Meth use? |
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Definition
| stared in west-midwest due to easier meth lab hiding. |
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Term
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Definition
| by the CPT 2D6 isoform of the P450 enzyme system (just like Ecstasy). |
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Term
| What is the primary neurotranmiter that Meth stimulates the release of? |
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Definition
| Dopamine. meth stimulates 600x normal dopamine release. |
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Term
| What are the acute physiological effects of taking Meth? |
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Definition
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Term
True or False Meth activates a reward pathway in the brain. |
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Definition
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Term
True or False Meth's neurotoxic effects are the most devastating & potentially permanent of its sequelae. |
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Definition
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Term
| What is the plasma half-life of Meth? |
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Definition
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Term
True or False Meth leads to a decrease in dopamine transporter levels. |
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Definition
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Term
| What are some expected medical complications related to Meth use? |
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Definition
MI & stroke (with long term use) Smoking meth R/T pulmonary HTN & dialated CM. immunomodulatory activity bruxisam and lovely preiodontal disease.
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Term
| What physical effects does Meth cause? |
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Definition
dramatic wt loss facial disfigurement social dysfunction jumpy eyes rapid eye movements PUPILS MAY BE DIALATED OR CONSTRICTED. dkin bumps
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Term
| What are some detremental S/E of taking Meth? |
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Definition
Rhabdo "tweaking"-doing same thing for hrs. severe HTN: can be 300/200 tachy,tachpnea, HYPERTHERMIA (like coke)
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Term
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Definition
Nodules, formed of toxins, that develop under the skin after using Meth. Addicts suck out the fluid & eat residue. |
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Term
| What are some psychiatric effects of taking Meth? |
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Definition
10% of Meth users have FRANK PSYCHOSIS Hypomania VIOLENT PHYSICAL & SEXUAL BEHAVIORS. Appetite suppression
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Term
| What is "Terrible Tuesday" withdrawl? |
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Definition
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Term
| What is significant about the course of chronic depression after abstinence from Meth? |
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Definition
| 62% of former users remain depressed 2-5y after stopping Meth use. |
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Term
True or False Craving for Meth can last up to 1y after stopping use. |
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Definition
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Term
| What are some long term cognitive effects of Meth use? |
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Definition
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Term
| What s/s can be expected in Meth withdrawl? |
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Definition
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Term
| Why is Wellbutrin not a good choice for tx of Meth addiction? |
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Definition
| Lowers seizure threshold. |
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Term
| How do we tx Meth addiction? |
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Definition
Tx substance-induced psy disorders. CELEXA 20mg PO QD Ambien 10mg Depakote for mood stabilization Zyprexa, Risperdal for phychosis/anxiety.
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Term
| What diagnostics should be ordered for your pt on Meth? |
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Definition
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Term
| What teaching should take place for the pt with Meth addiction? |
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Definition
Motivational interviewing harm reduction Adherence strateies while using Decrease STD transmission Decrease HIV spread. Gay/Lesbian centered tx avail.
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