Shared Flashcard Set

Details

Menanoma
MS Module
26
Medical
Graduate
05/22/2009

Additional Medical Flashcards

 


 

Cards

Term
What is the differential diagnosis of a pigmented skin lesion? (9)
Definition

melanoma

cafe au lait spots

Peutz Jeghers

Nevus

Freckle (ephelis)

Hemorrhage

Granulation tissue

Angioma

Lentigo

Term
What skin characteristic are freckles and melanomas common in?
Definition
fair skin
Term
Which type of pigmented lesion will change color in the sun?
Definition
freckle not a lintigo
Term
Which type of pigmented lesion has an increase in melanocytes?
Definition
lintigo not freckle
Term
What is the medical term for a mole?
Definition
nevus
Term
Wat is the medical term for a freckle?
Definition
ephelis
Term
What genetic mutation is seen in a nevus?
Definition
BRAF
Term

What is the shape of a junctional nevus?

 

Where are they located?

Definition

flat

 

epidermis

Term
Where is a compound nevus located in the skin?
Definition
between the epidermis and dermis
Term
Where is an intradermal nevus located?
Definition
in the dermis (of course)
Term

Which type of malignancy is due to intermitant sun exposure?

 

Which two are more associated with extended exposure?

Definition

melanoma

 

sqaumous cell and basal cell carcinomas

Term

What genetic loss accompanies melanoma?

 

What does this mutation lead to?

Definition

E-cadherin

signals it to invade

Term
What is a dysplastic nevi?
Definition
a premalignant lesion worse than a nevus
Term
What makes hemorrhage, granulation tissue, and angioma be put at the bottom of the diffential when the dx is likely melanoma?
Definition
hemorrhage, granulation tissue, and angioma go away
Term
What is Peutz Jeghers associated with?
Definition

GI tract involvement

lentigo like macules on lips

Term
What layer of the epidermis is involved with in a lentigo?
Definition
basal layer
Term

What are the four types of melanomas?

 

 

Which is most common?

Definition

lentigo

superficial spreading (most common)

Acral melanoma

Nodular

Term
What is a Hutchenson's Freckle?
Definition
Lentigo meligna
Term
Where do lentigo maligna often effect anatomically on the body?
Definition
head and neck
Term

What is the prognosis of a nodular or Acral melanoma?

 

For each, why?

Definition

bad

 

nodular bad prognosis b/c verticle growth

acral bad prognosis b/c often caught late due to locatoin of incidence

Term
Where do acral melanomas effect the body?
Definition

under the nails

palms

sole

Term
What races are Acrul melanomas most common in?
Definition

Asian

African American

Term
What scale is used most commonly to evaluate depth of a melanoma?
Definition
Breslow
Term
In Breslow thickness what is the number that cuts off a thin melanoma which is curable to a more difficult melanoma?
Definition
<0.76 mm is thin
Term
What is the gold standard treatment for melanoma?
Definition
surgery
Term
What melanoma chemotherapy drug is the only one FDA approved?
Definition
Dacarbazine
Supporting users have an ad free experience!