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Medications
Jackson County Drug Protocols
32
Medical
Professional
11/27/2011

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Cards

Term
Acetaminophen
Ind/Contra
Dosage
Definition
Ind: Fever>102.2 in children ,12y/o
had seizure, appear toxic, prolonged transport tme
Contra:hyperthermia from environment
15mg/kg Oral/rectal supository
Term
ASA Asprin
Definition
I:cardiac CP, Barotrauma
C:ACtive GI Bleed
D: CP-162mg BT:324mg
Term
Activated Charcoal
Definition
I:Oral toxic injestion within 1 hr after consult with OLMC
C:injestion of mineral acids or alkalispetroleum products or cyanide
D:25-50g/ Ped 0.5g/kg
Term
Adenosine
Definition
I:Supraventricular tachycardia
D:Known Wolff-Parkinson-White syndrome.
Sick sinus syndrome or second or third degree heart block without functioning pacemaker
D:6 mg rapid IV push over 1- 2 seconds followed by 20 ml saline rapid IV
push at next most proximal IV port, preferably through a large bore
antecubital site.
If no conversion, 12 mg rapid IV push over 1-2 seconds followed by 20
ml saline rapid IV push at next most proximal IV port in 1-2 minutes.
May repeat 12 mg dose once in 1-2 minutes.
Pediatric: 0.1 mg/ kg rapid IV or IO push over 1- 2 seconds with 10 ml saline
rapid IV push at proximal IV port. May repeat with 0.2 mg/kg in 1-2
minutes.
Term
Albuterol
Definition
I:Bronchospasm due to asthma, COPD, CHF or anaphylaxis
D:2.5-3 mg via nebulizer with oxygen set at 6 - 10 L/min MAY REPEAT 2X
Term
AMIODARONE
Definition
I:Ventricular fibrillation or pulseless ventricular tachycardia.
● Ventricular tachycardia with a pulse in a stable patient.
● After conversion to a perfusing rhythm from ventricular tachycardia or fibrillation.
D:Ventricular fibrillation/Pulseless ventricular tachycardia:
300 mg IV or IO bolus in 20 - 30 ml normal saline.
If no perfusing rhythm an additional 150 mg IV or IO bolus in
3 - 5 minutes.
Ventricular tachycardia with a pulse:
150 mg in 10 – 100 ml normal saline IV or IO over 10 minutes
Repeat once in 10 minutes if no change in rhythm.
Post-conversion from ventricular fibrillation or tachycardia to a perfusing rhythm:
150 mg in 10 – 100 ml normal saline IV or IO over 10 minutes.
Total maximum dose of 450 mg
Pediatric dose = 5 mg/kg up to adult dose.
Term
ATROPINE SULFATE
Definition
I:Symptomatic bradycardia.
● Antidote for symptomatic organophosphate poisoning
D:Adult: 0.5 mg IV or IO push every 3-5 minutes.
Maximum dose 3 mg.
Pediatric: 0.02 mg/kg IV or IO every 3-5 minutes.
Minimum single dose: 0.1 mg.
Maximum single dose: 0.5 mg in child, 1.0 mg in adolescentOrganophosphate poisoning:
Double dose every 5 minutes until symptoms controlled.
Term
CALCIUM GLUCONATE
Definition
INDICATIONS:
● Antidote for overdoses of calcium channel blockers or magnesium.
● Topical treatment for hydrogen fluoride or hydrofluoric acid exposure.ROUTE & DOSAGE:
EMT - P:
Calcium Channel Blocker
or
Magnesium Sulfate overdose:
Adult: 10 ml IV or IO over 5-10 minutes. Pediatric: 0.6 - 0.75 ml/kg IV or IO over 5-10 minutes.
Hydrogen fluoride or hydrofluoric acid exposure :
Apply topically - (mix 1 ampule in 1 ounce (30cc) K-Y jelly)
Term
DIAZEPAM
Definition
INDICATIONS:
● Sedation for painful procedures (such as trancutaneous pacing or
cardioversion), amputations or combative patients.
● Muscle relaxation for patients with dislocations, fractures, or significant
muscle spasms.
● Post RSI sedation.
● Seizures.
ROUTE & DOSAGE:
EMT - P:
Adult: 2-10 mg IV, IO or IM every 3-5 mins
Max of 10 mg for sedation.
Max of 20mg for seizures.
May be given rectally for seizures.
Pediatric: 0.1-0.3 mg/kg IV, IO or IM (maximum dose 5 mg). May
repeat once.
0.5 mg/kg rectal (maximum dose 5 mg).
Term
DIPHENYDRAMINE
Definition
INDICATIONS:
● Less effective and longer acting than epinephrine for use in mild to moderate
anaphylactic or allergic reactions.
● Dystonic reactionsROUTE & DOSAGE:
Adult: 25-50 mg IV, IO, IM or orally
Pediatric: 1-2 mg/kg IV, IO, IM or orally
EMT - I for mild to moderate anaphylactic or allergic reactions.
EMT - P for acute dystonic reactions.
Term
DOPAMINE
Definition
INDICATIONS:
● Symptomatic bradycardia unresponsive to atropine
Hypotension not responding to volume replacement.
CONTRAINDICATIONS:
N Hypotension without adequate volume replacementROUTE & DOSAGE:
Symptomatic Bradycardia: 2-10 mcg/kg/min IV or IO infusion titrated
.
Shock: 2-20 mcg/kg/min IV or IO infusion titrated to desired effect.
Dopamine (Intropin) 400 mg in 250 (1600 mcg/ml)
Microdrops per minute (or ml/hr)
Term
EPI
Definition
INDICATIONS:
Ventricular fibrillation, pulseless ventricular tachycardia, asystole, PEA.
● Symptomatic bradycardia.ROUTE & DOSAGE:
Anaphylaxis (hypotension, bronchospasm, angioedema, itching, hives):
Adult: 0.3 - 0.5 mg = 0.3 - 0.5 ml of 1:1,000 SQ.
May repeat in 3-5 minutes.
Pediatric: 0.01 mg/kg = 0.01 ml/kg of 1:1,000 SQ.
Maximum 0.5 mg/dose. May repeat in 3-5 minutes.
Auto-injector:
0.3 mg if weight ≥ 66 pounds
0.15 mg if weight 13 - 66 pounds
May repeat in 3-5 minutes
(Over)
EMT - I:
Asthma or anaphylaxis
Adult: 0.3 - 0.5 mg = 0.3 - 0.5 ml of 1:1,000 IM or
0.1 mg = 1 mL of 1:10,000 IV or IO.
May repeat in 3-5 minutes.
Pediatric: 0.01 mg/kg = 0.01 ml/kg of 1:1,000 IM or
0.01 mg/kg = 0.1 ml/kg of 1:10,000 IV or IO.
Maximum 0.5 mg/dose. May repeat in 3-5 minutes.
Cardiac Arrest
Adult: Initial dose: 1 mg of 1:10,000 IV or IO.
May repeat every 3-5 minutes.
Pediatric: Initial dose: 0.01 mg/kg (0.1 ml/kg of 1:10,000) IV or IO or
May repeat every 3-5 minutes.
Neonates: 0.01 - 0.03 mg/kg (0.1 - 0.3 ml/kg of 1:10,000) IV, IO, ET or UV.
May repeat every 3-5 minutes.
EMT - P:
Cardiac Arrest - if no other route available. May repeat every 3-5 minutes
Adult: 2 mg of 1:1,000 diluted in 5-10 ml NS ET
Pediatric: 0.1 mg/kg (0.1 ml/kg of 1:1,000) diluted in 5-10 ml NS ET
Epinephrine Infusion
Anaphylactic shock or severe bradycardia by online medical control only
Adult: mix 1 mg (1:1,000) in 250 ml (4 mcg/ml) or
500 ml (2 mcg/ml) normal saline.
2 - 10 mcg/minute IV or IO titrated to desired effect.
Pediatric: mix 1 mg (1:1,000) in 500 ml (2 mcg/ml) or
1000 ml (1 mcg/ml) normal saline.
0.1 - 1 mcg/kg/minute IV or IO titrated to desired effect
● Anaphylaxis.
● Asthma.
N Known sensitivity to epinephrine.
CONTRAINDICATIONS:
N Cardiac chest pain.
Term
eTOMIDATE
Definition
SEDATION FOR RSI
SIDE EFFECTS & PRECAUTIONS:
Administer in a large bore, free flowing IV or IO.
Respiratory depression, hypotension and cardiopulmonary arrest are more likely
in the elderly, those with COPD, renal, heart or liver disease. Use with
caution in the presence of alcohol, barbiturates, narcotics or
benzodiazopines.
Skeletal muscle jerking or movements occur commonly.
Duration is 4-10 minutes.
ROUTE & DOSAGE:
EMT - P: Adult: 0.3 mg/kg IV or IO over 30 - 60 seconds.
Typical adult dose is 20 mg.
0.15 - 0.2 mg/kg IV or IO if elderly, debilitated
or hypotensive.
Pediatric: 0.3 mg/kg IV or IO over 30 - 60 seconds.
Term
FENTANYL
Definition
INDICATIONS:
• Severe burns without airway compromise.
• Cardiac chest pain.
• Abdominal pain.
N Known sensitivity to fentanyl.
CONTRAINDICATIONS:
Rapid injection can cause respiratory arrest or chest wall rigidity.
Give over 30-60 seconds.
SIDE EFFECTS & PRECAUTIONS:
Central nervous system depressant, which can cause respiratory depression,
peripheral vasodilation, decreased cardiac output and pupillary constriction.
Avoid using if morphine has been given. If morphine given previously wait, at
least 5-10 minutes before giving fentanyl and then give cautiously in small
amounts.
Do not use if systolic BP < 90 mm Hg or SpO2 < 90%.
Use with caution (smaller or less frequent doses) in the elderly.
Naloxone (Narcan) will reverse the respiratory effects of fentanyl.
EMT – I, P:
ROUTE & DOSAGE:
Adult: 50 micrograms (mcg) IV or IO slow over 30-60 seconds, then
25 - 50 mcg IV or IO every 3-5 minutes as needed for severe
pain. May be given intranasal or IM if IV or IO is unavailable.
Maximum dose 200 mcg.
Pediatric: 1 microgram (mcg)/kg IV or IO slow over 30-60 seconds, then
0.5 - 1 mcg/kg IV or IO every 3-5 minutes as needed for
severe pain up to 4 mcg/kg maximum dose. May be given
intranasal or IM if IV or IO is unavailable. Maximum dose 200
mcg.
AEROMEDICAL only:
IV Infusion: 0.5 - 4 mcg/kg/hour IV infusion. Titrate to desired effect.
Term
Glucagon hydrochloride
Definition
INDICATIONS:
● Documented hypoglycemic reaction in an unconscious or semi-conscious
patient where an IV or IO can not be established.
● Significant beta blocker poisoning.
CONTRAINDICATIONS:
N Known sensitivity to glucagon hydrochlorideROUTE & DOSAGE:
EMT - I:
For Hypoglycemia:
Adult: 1 mg (1 unit) IM or SQ (May be repeated twice if needed)
Pediatric: <20 KG: 0.5 mg (0.5 unit) IM or SQ
>20 KG: 1 mg (1 unit) IM or SQ
EMT - P:
Beta Blocker Overdose:
Adult: 3-5 mg IV or IO every 5 minutes, maximum 15 mg
Term
Glucose/Dextrose
Definition
Symptomatic hypoglycemia, blood sugar less than:
● 80 mg/dl in an Adult.
● 60 mg/dl in a Child (1 year to Puberty).
● 40 mg/dl (Birth to 1 year).
Term
Halidol
Definition
Sedation and restraint of patients who have a head injury, are combative or
are intubatedCONTRAINDICATIONS:
N Known sensitivity to haloperidol.
N Observed or suspected seizure.
N Prolonged QT interval.
N Pregnancy.ROUTE & DOSAGE:
EMT - P:
Adult: Administer 2.5 mg to 5 mg IV, IO or IM.
May repeat up to 10 mg maximum.
Pediatric: 0.03-0.07 mg/kg slow IV or IO. Maximum 2.5 mg.
Term
Atrovent
Definition
TRADE NAME:
Atrovent
ACTION:
Atrovent is an anticholinergic (parasympatholytic) bronchodilator.
INDICATIONS:
COPD, bronchospasm or asthma.
CONTRAINDICATIONS:
1 Known sensitivity to ipratropium bromide or atropine.
SIDE EFFECTS & PRECAUTIONS:
Use with caution in patients with narrow angle glaucoma, prostrate hypertrophy
or bladder neck obstruction.
ROUTE & DOSAGE:
EMT – I, P: 1 unit dose (0.5 mg) via nebulizer. May be mixed with albuterol.
May repeat twice at 10-15 minute intervals
Term
Lidocaine
Definition
TRADE NAME:
Local anaesthetic.
ACTION:
● Pretreatment during rapid sequence intubation for increased intracranial
pressure or bronchospasm.
INDICATIONS:
● IO infusion in conscious patients.
N Known sensitivity to lidocaine.
CONTRAINDICATIONS:
Toxicity can produce altered mental status, myocardial depression, and seizures.
SIDE EFFECTS & PRECAUTIONS:
EMT–I:
ROUTE & DOSAGE:
IO infusion in conscious patients
0.5 mg/kg of 2% Lidocaine (Preservative Free) IO.
EMT–P: Pretreatment for Rapid Sequence Intubation (RSI)
1.5 mg/kg IV or IO if bronchospasm or suspected increased
intracranial pressure (ICP)
Term
Mag Sulfate
Definition
TRADE NAME:
Antiarrhythmic, anticonvulsant, bronchial smooth muscle relaxant, central
nervous system depressant.
ACTION:
● Torsades de Pointes. Refractory ventricular fibrillation or tachycardia.
INDICATIONS:
● Eclampsia.
● Asthma.
None.
CONTRAINDICATIONS:
Toxicity may produce decreased level of consciousness, decreased reflexes,
hypotension or respiratory depression. Rapid administration may result in
flushing, sweating, mild bradycardia or hypotension.
SIDE EFFECTS & PRECAUTIONS:
EMT - P:
ROUTE & DOSAGE:
Cardiac arrest: 1 - 2 grams in 10 ml saline IV or IO push.
Non-cardiac arrest: 1 - 2 grams in 10 ml saline over 1-3 minutes IV or IO.
Pediatric: 25-50 mg/kg IV or IO up to adult maximum.
Term
Midasolam
Definition
TRADE NAME:
A short acting benzodiazepine, causing central nervous system depression,
respiratory depression, skeletal muscle relaxation and amnesia.
ACTION:
• Seizures
INDICATIONS:
• Sedation for painful procedures (such as trancutaneous pacing or
cardioversion), amputations, severe muscle spasms, or combative patients.
• Post RSI sedation.
N Known sensitivity to midazolam.
CONTRAINDICATIONS:
Administer in a large bore, free flowing IV.
SIDE EFFECTS & PRECAUTIONS:
Respiratory depression, hypotension or sedation are common, particularly in the
elderly, in those with chronic disease or in the presence of other sedating
agents: alcohol, barbiturates, benzodiazepines or opiates.
Paradoxical excitement or agitation may occur.
EMT - P:
ROUTE & DOSAGE:
Adult: 1-5 mg IV or IO at 1 mg/minute. May be given intranasal if
IV or IO unavailable.
May repeat to a maximum total dose of 20 mg.
Pediatric: 0.02 - 0.08 mg/kg IV or IO over 1 - 2 minutes. May be given
intranasal if IV or IO unavailable.
May repeat to a maximum total dose of 0.2 mg/kg
Term
morphine
Definition
TRADE NAME:
Narcotic analgesic and vasodilator.
ACTION:
• Cardiac chest pain.
INDICATIONS:
• Extremity fractures, crush or amputation injuries in the absence of head,
chest and abdominal injuries.
• Abdominal pain.
• Severe burns.
N Known sensitivity to morphine.
CONTRAINDICATIONS:
Central nervous system depressant, which can cause respiratory depression,
peripheral vasodilation, decreased cardiac output or pupillary constriction.
SIDE EFFECTS & PRECAUTIONS:
May cause hypotension or nausea, especially if given rapidly; always administer
slowly with dilution.
Naloxone (Narcan) is a specific narcotic antagonist which can reverse morphine
induced respiratory depression.
EMT - I:
ROUTE & DOSAGE:
Adult:
2 - 5 mg slow IV or IO every 5 minutes as
needed to a total dose of 20 mg.
10 mg IM, if IV and IO unavailable.
EMT- P:
Pediatric:
0.05 - 0.2 mg/kg slow IV or IO every 5
minutes to a total dose of 10 mg.
0.1 - 0.2 mg/kg IM, if IV and IO
unavailable. Maximum 10 mg.
Term
Narcan
Definition
TRADE NAME:
Narcotic antagonist.
ACTION:
Reverse suspected or known narcotic induced respiratory depression due to:
morphine, heroin, fentanyl, hydromorphone (Dilaulid), oxycodone (Percodan),
meperidine (Demerol), methadone (Dolophine), hydrocodone (Vicodin),
codeine, diphenoxylate (Lomotil), propoxyphene (Darvon), pentazocine
(Talwin), nalbuphine (Nubain).
INDICATIONS:
N Known sensitivity to naloxone.
CONTRAINDICATIONS:
The narcotic dependent patient may experience frank withdrawal after
administration. Be prepared to restrain these patients as they may become
angry or violent. The goal is to keep the patient out of respiratory depression
but not fully conscious. Rapid administration may cause nausea. Repeated
and large doses may be needed.
SIDE EFFECTS & PRECAUTIONS:
ROUTE & DOSAGE:
EMT- I, P: Adult: 0.4 - 1 mg titrated to reverse respiratory depression IV,
IO, intranasal , IM or SQ. (May give 0.8 - 2 mg ET if
IV/IO access unavailable in cardiac arrest.)
Repeat every 1-3 minutes. Maximum 10 mg.
Pediatric: 0.1 mg/kg (max 0.4 mg/dose) titrated to reverse
respiratory depression IV, IO, intranasal , IM, SQ or UV
in a neonate.
Repeat every 1-3 minutes. Maximum 10 mg.
Term
nitro
Definition
TRADE NAME:
IV: Tridil, NITRO-BID IV (by physician order only for aeromedical or inter-hospital
transport – must be provided by the sending hospital for inter-hospital ground transport)
Smooth muscle relaxant, including that is arteries and veins.
ACTION:
• Chest pain of cardiac origin.
INDICATIONS:
• CHF or Pulmonary edema.
• Unstable angina during aeromedical or inter-hospital transport by physician order only.
N Known sensitivity to nitroglycerin.
CONTRAINDICATIONS:
N Sildenafil (Viagra) or vardenafil (Levitra) use within the preceding 24 hours.
N Tadalafil (Cialis) use within the preceding 48 hours.
May cause hypotension or reflex tachycardia; IV access desirable. Nitroglycerin loses its
potency with time. Do not shake nitroglycerin spray prior to administration. Warn
patients of throbbing headache, flushing, dizziness and burning under the tongue.
SIDE EFFECTS & PRECAUTIONS:
EMT - B: Cardiac chest pain: May assist in self administration of patient’s own
nitroglycerin for chest pain.
ROUTE & DOSAGE:
EMT - I: Cardiac chest pain: 0.4 mg SL if systolic blood pressure > 90 mm Hg. May
repeat twice at 3-5 minute intervals as long as systolic blood pressure is > 90
mm Hg.
CHF/Pulmonary Edema: 0.4 mg SL. May repeat up to 4 times at 3-5
minute intervals as long as systolic blood pressure is > 90 mm Hg.
EMT - P: Angina or cardiac chest pain
0.4 mg SL if blood pressure > 90 mm Hg systolic. May repeat twice at 3-5
minute intervals as long as systolic blood pressure is > 90 mm Hg.
Unstable Angina (by physician order only during aeromedical or interhospital transport)
Titrate IV infusion by 5-10 mcg/min until desired effect. To wean off IV
infusion, decrease by 5 mcg every 5-10 minutes until desired response.
Term
nitrous oxide
Definition
TRADE NAME:
Nitronox, N2O2
ACTION:
Inhalation analgesic.
INDICATIONS:
• Acute musculoskeletal pain
• Contact burns without risk of smoke inhalation
CONTRAINDICATIONS:
1 Known sensitivity to nitrous oxide.
1 Inability of patient to self-administer.
1 Pregnancy in patient, medic or bystanders.
1 Head injury.
1 Airway burn or respiratory distress.
SIDE EFFECTS & PRECAUTIONS:
Respiratory depression, drowsiness. Use with caution in patients with chest
trauma or lung disease.
ROUTE & DOSAGE:
EMT - P: Patient self administered by inhalation.
Term
zofran
Definition
TRADE NAME:
Potent anti-emetic agent, a selective 5-HT3 receptor antagonist.
ACTION:
• Nausea or vomiting
INDICATIONS:
• Prophylactically to prevent nausea or vomiting
N Known sensitivity to ondansetron.
CONTRAINDICATIONS:
N Recent administration of apomorphine (given subcutaneous for Parkinson’s
Disease) – apomorphine is rarely used – may cause severe hypotension
May cause minor headache, constipation or diarrhea.
SIDE EFFECTS & PRECAUTIONS:
0.1 mg/kg (max dose = 4 mg) slow IV, IO, or IM.
EMT – I: May repeat initial dose once in 5 minutes.
ROUTE & DOSAGE:
EMT – P: 8 mg oral dissolving tablet if age > 12. May repeat once in
15 minutes.
Term
oxymetazoline
Definition
TRADE NAME:
Afrin
ACTION:
Potent sympathomimetic arterial constrictor.
INDICATIONS:
Epistaxis.
Pretreatment for nasotracheal intubation.
CONTRAINDICATIONS:
1 Known sensitivity to oxymetazoline.
1 Persistent blood pressure greater than 190/110.
SIDE EFFECTS & PRECAUTIONS:
Tachycardia, myocardial ischemia or cardiac dysrhythmia.
HOW SUPPLIED:
Spray bottle
ROUTE & DOSAGE:
EMT - P: Two sprays into the affected nostril(s). Repeat as needed.
Term
oxytocin
Definition
TRADE NAME:
Pitocin
ACTION:
Polypeptide hormone which stimulates uterine contraction.
INDICATIONS:
Control of postpartum hemorrhage following delivery of the placenta.
CONTRAINDICATIONS:
N Known sensitivity to oxytocin.
N Pregnancy.
SIDE EFFECTS & PRECAUTIONS:
Nausea and vomiting. Severe uterine cramps.
ROUTE & DOSAGE:
EMT - P: 10-20 units IV or IO added to 1000 ml of normal saline and run
wide open or as needed to control bleeding.
Term
propofol
Definition
TRADE NAME:
Diprivan
ACTION:
Sedation
INDICATIONS:
Aeromedical or inter-hospital transport by physician order only – must be
provided by the sending hospital for inter-hospital ground transport
Maintenance of sedation in ventilated patients during inter-hospital transport
N Known sensitivity to propofol
CONTRAINDICATIONS:
N Allergy to soybean oil
N Allergy to egg lecithin
N Allergy to glycerol
N Use in a non-intubated patient
N Age less than 3 years
SIDE EFFECTS & PRECAUTIONS:
Ensure total asepsis when preparing drip.
Will cause profound decrease in CNS activity, hypotension and respiratory
depression particularly if used with sedatives or narcotics.
Rarely causes increase in ICP. Use with caution in head injured patients or those
with acute CVA.
Decrease dose 20-50% if age greater than 55 years or debilitated.
ROUTE & DOSAGE:
EMT – P or RN: IV only - typically 5 - 50 mcg/kg/min.
Maintain established rate and follow physician ordered parameters.
Increase 5-10 mcg/kg/min every 5 - 10 minutes to increase level of sedation
as needed.
Decrease rate 5-10 mcg/kg/min every 5 - 10 minutes to decrease level of
sedation for systolic blood pressure less than 90 mm Hg
Term
sodium bicarb
Definition
TRADE NAME:
Sodium bicarbonate
ACTION:
Alkalinizing agent. Raises blood pH.
INDICATIONS:
& Tricyclic antidepressants overdoses with hypotension, dysrhythmias, seizures
or QRS > 0.12.
& Hyperkalemia.
& Severe acidosis refractory to hyperventilation.
CONTRAINDICATIONS:
N Alkalosis.
SIDE EFFECTS & PRECAUTIONS:
May deactivate catecholamies. Precipitates with calcium in IV tubing.
Decreases chance of brain viability in cardiac arrest.
HOW SUPPLIED:
8.4%: 50 mEq/50 ml prefilled syringe
4.2%: 5 mEq/10 ml prefilled syringe
ROUTE & DOSAGE:
EMT - P:
Adult: 1 mEq/kg of 8.4% IV or IO. Repeat 0.5 mEq/Kg every 10
minutes.
Pediatric: 1 mEq/kg of 4.2% IV or IO. Repeat 0.5 mEq/kg every 10
minutes.
Term
Succinylcholine chloride
Definition
TRADE NAME:
Anectine
ACTION:
Depolarizing skeletal muscle relaxant.
INDICATIONS:
● Rapid sequence intubation paralysis.
CONTRAINDICATIONS:
1 Known sensitivity to succinylcholine chloride.
1 History or family history of malignant hyperthermia.
1 Known severe hyperkalemia
1 History of stroke, burns, crush injuries > 4 days and < 6 months previously.
1 Quadriplegia, paraplegia, muscular dystrophy, multiple sclerosis, amyotrophic
lateral sclerosis (ALS) or other neuromuscular disorder of > 4 days duration.
1 History of masseter muscle spasm.
SIDE EFFECTS & PRECAUTIONS:
Succinylcholine chloride causes paralysis, not analgesia or amnesia; conscious
patients must receive sedation. Patient will require airway management and
ventilation.
Patients with neuromuscular disorders of > 4 days and healed< 6 months
duration are at risk for fatal hyperkalemia, as are patients with ongoing
neuromuscular disorders, such as muscular dystrophy, multiple sclerosis, or
amyotrophic lateral sclerosis.
Use with caution in patients with renal failure on dialysis who have severe
hyperkalemia.
ROUTE & DOSAGE:
EMT - P: 2 mg/kg IV or IO
Term
Vecuronium
Definition
TRADE NAME:
Non-depolarizing skeletal muscle relaxant.
ACTION:
● To provide paralysis (paralyzing dose) for rapid sequence intubation if
succinylcholine is contraindicated.
INDICATIONS:
● To maintain paralysis (maintenance dose) after intubation after adequate
sedation is provided.
● To relieve isolated masseter muscle spasm due to succinylcholine.
N Known sensitivity to vecuronium.
CONTRAINDICATIONS:
Vecuronium causes paralysis, not analgesia or amnesia; patients must receive
adequate sedation. Patient will require airway management and ventilation.
SIDE EFFECTS & PRECAUTIONS:
EMT - P:
ROUTE & DOSAGE:

Paralyzing Dose: 0.15 mg/kg IV or IO. Usual adult dose is 10 mg.
Administer only after paralysis due to
succinylcholine has begun to wear off as
evidenced by patient movement.
Maintenance Dose: 0.01-0.015 mg/kg IV or IO 25-40 minutes after
initial paralysis, then every 12-15 minutes as
needed or 1 mcg/kg/min IV or IO infusion.
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