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Medical Vocab Ch #19 Cancer Medicine - Oncology (Neoplasms)
Medical Coding & Billing Word Structures & Vocab.
159
Medical
Undergraduate 1
04/28/2010

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Term
adenocarcinoma
Definition
Cancerous tumor of glandular tissue.
Term
adjuvant therapy
Definition
Treatment of disease with substances that assist or enhance the action of primary treatment.
Term
alkylating agents
Definition
Synth chemicals used in treatment of cancer, interfering w/DNA synthesis & cell division to prevent cancer cells from increa
Term
alopecia
Definition
Partial or complete lack of hair.
Term
alveolar
Definition
Pertaining to tumor growth in small microscopic sacs ; small sac or alveolus.
Term
anaplasia
Definition
Loss of differentiation of cells and reversion to a more primitive, unspecialized cell type.
Term
angiogenesis
Definition
Process of forming new blood vessels.
Term
antibiotics
Definition
Chemical substances produced by bacteria or primitive plants; inhibit the growth of cells & used in treatment of cancer & infectious disease.
Term
antimetabolites
Definition
Chemicals that prevent cell division by inhibiting formation of substances necessary to make DNA; used in cancer trtmnt
Term
antimitotics
Definition
Drugs that block mitosis (cell division); used to treat cancer.
Term
apoptosis
Definition
Programmed cell death.
Term
benign tumor
Definition
Noncancerous growth.
Term
biologic response modifiers
Definition
Substances produced by normal cells that block tumor growth or stimulate the immune system to fight cancer.
Term
biological therapy
Definition
Treatment using the body’s own defense mechanisms to fight tumor cells.
Term
Bone marrow biopsy
Definition
Small amount of bone marrow tissue is removed (aspirated) & examined under micro for evid of malignancy
Term
Bone marrow transplant
Definition
Bone marrow tissue is infused intravenously into a patient
Term
brachytherapy
Definition
Implantation of small, sealed containers or seeds of radioactive material directly  or near tumors.
Term
cachexia
Definition
General ill health and malnutrition associated with chronic disease such as cancer.
Term
Carcinogen
Definition
Substance that produces cancer
Term
carcinoma
Definition
Malignant (cancerous) tumor
Term
carcinoma in situ
Definition
Localized tumor growth.
Term
Cauterization
Definition
Process of burning tissue to destroy it.
Term
cellular oncogenes
Definition
Pieces of DNA that when broken or dislocated can cause a normal cell to become malignant.
Term
chemotherapy
Definition
Treatment with drugs.
Term
Combination chemotherapy
Definition
Use of several chemotherapeutic agents together for treatment of tumors
Term
cryosurgery
Definition
Destruction of tissue using cold temperatures.
Term
cystic tumor
Definition
Tumor forms with large open spaces filled with fluid.
Term
dedifferentiation
Definition
Loss of differentiation of cells & reversion to more primitive, unspecialized type; anaplasia or undifferentiation
Term
Deoxyribonucleic acid DNA
Definition
Genetic material within the nucleus of a cell; controls cell division & protein synthesis
Term
Differentiating agents
Definition
Drugs that promote tumor cells to differentiate, stop growing and die
Term
differentiation
Definition
Specialization of cells
Term
dysplastic
Definition
Pertaining to abnormal growth of cells but not clearly cancerous.
Term
electrocauterization
Definition
Burning tissue to destroy it.
Term
Electron Beams
Definition
Low-energy beams of radiation for treatment of skin or surface tumors.
Term
en bloc resection
Definition
Removal of a tumor with a large area of surrounding tissue containing lymph nodes.
Term
encapsulated
Definition
Surrounded by a capsule; benign tumors are encapsulated.
Term
epidermoid
Definition
Resembling epidermal tissue (tumors that arise from aberrant epidermal cells).
Term
excisional biopsy
Definition
Removal of tumor and a margin of normal tissue.
Term
exenteration
Definition
Wide resection involving removal of the tumor, organ of origin, & all surrounding tissue in the body space.
Term
exfoliative cytology
Definition
Cells are scraped from a region of suspected disease and examined under the microscope.
Term
external beam radiation
Definition
Radiation applied to a tumor from a distant source, such a machine (linear accelerator).
Term
fiberoptic colonoscopy
Definition
Visual examination of the colon using a fiberoptic instrument (endoscope).
Term
fibrosarcoma
Definition
Malignant tumor of fiber-producing cells (flesh or connective tissue origin).
Term
fibrosis
Definition
Abnormal condition of fibrous connective tissue; occurring in the lung as a side effect of radiation for lung cancer.
Term
follicular
Definition
Pertaining to microscopic description of tumor growth in small, gland-type sacs.
Term
fractionation
Definition
Method of administering radiation treatment in small, repeated doses rather than in a few large doses.
Term
fulguration
Definition
Destruction of tissue by electric sparks generated by a high-frequency current.
Term
fungating tumor
Definition
Mushrooming pattern of growth in which tumor cells pile one on top of another & project from tissue surface.
Term
genetic screening
Definition
Family members are tested to determine whether they have inherited a cancer-causing gene.
Term
grading of tumors
Definition
Evaluate microscopic appearance of tumor cells & determine their degr of differentiation /maturity & thus malig transform
Term
gray
Definition
Unit of absorbed radiation dose.
Term
gross descript of tumors
Definition
Visual appearance of tumors, such as cystic, fungating, inflammatory, medullary, necrotic, polypoid, ulcerating & verrucous.
Term
hyperplasia
Definition
Condition of increased formation (increase in number of cells).
Term
incisional biopsy
Definition
Piece of tumor is removed for examination to establish a diagnosis.
Term
infiltrative
Definition
Pertaining to extending beyond normal tissue boundaries.
Term
invasive
Definition
Having the ability to enter and destroy surrounding tissue.
Term
irradiation
Definition
Exposure to any form of radiant energy such as light, heat or x-rays.
Term
laparoscopy
Definition
Visual examination of the abdominal cavity using small incisions and a laparoscope (endoscope).
Term
linear accelerator
Definition
Device that produces high-energy x-ray (photon) beams for treatment of deep-seated tumors.
Term
malignant tumor
Definition
Cancerous tumor.
Term
mammography
Definition
X-ray examination of the breast.
Term
medullary tumor
Definition
Large, soft, fleshy tumors.
Term
mesenchymal
Definition
Pertaining to embryonic connective tissue from which all connective tissues arise.
Term
Metaplasia
Definition
Conversion of normal cells into a less differentiated type in response to chronic stress or injury.
Term
metastasis
Definition
Beyond control; spreading of a cancerous tumor from its original location to a distant site.
Term
Microscopic description of tumors
Definition
Appearance of tumors as viewed under the microscope.
Term
mitosis
Definition
Cell division or replication of cells; creation of two identical daughter cells from a parent cell.
Term
mixed tissue tumors
Definition
Tumors composed of different types of tissue (epithelial as well as connective tissues).
Term
modality
Definition
Method of treatment.
Term
molecularly targeted drugs
Definition
Anticancer drugs designed to block the function of growth factors, their receptors, & signaling pathways in specific tumor
Term
morbidity
Definition
Damage to normal tissue or the state of being diseased.
Term
mucinous
Definition
Pertaining to cystic tumors filled with mucus.
Term
mucositis
Definition
Inflammation of mucous membranes; often a side effect of radiation therapy or chemotherapy.
Term
mutagenic
Definition
Pertaining to producing mutation.
Term
mutation
Definition
Change in the genetic material (DNA) of a cell.
Term
myelosuppression
Definition
Stopping or inhibiting the growth of bone marrow tissue (blood cells (leukocytes, erythrocytes, and platelets)
Term
necrotic tumor
Definition
Tumor containing dead cells.
Term
needle (core) biopsy
Definition
Insertion of a needle into tissue to remove a core of cells to examine under a microscope; needle aspiration.
Term
neoplasm
Definition
New growth; new formation (tumor benign or malignant).
Term
neuroblastoma
Definition
Cancerous tumor of embryonic nervous tissue; a sarcoma made of neuroblasts and affecting infants & children up to 10
Term
nucleotide
Definition
Unit of DNA (gene) composed of a sugar, phosphate, and a base.
Term
oncogene
Definition
Region of DNA in tumor cells (cellular oncogene) or in viruses (viral oncogene) that cause cancer.
Term
oncology
Definition
Study of tumors (malignant tumors).
Term
osteosarcoma
Definition
Malignant tumor (flesh tissue) of bone.
Term
palliative
Definition
Relieving, but not curing symptoms.
Term
papillary
Definition
Pertaining to tumors that grow in small, nipple-like or finger-like pattern.
Term
pedunculated
Definition
Possessing a stem or stalk (peduncle).
Term
pharmacokinetics
Definition
Study of the distribution and removal of drugs in the body over a period of time.
Term
photon therapy
Definition
Radiation treatment using x-rays and gamma rays delivered to tumor tissue via a linear accelerator.
Term
pleomorphic
Definition
Pertaining to tumors that contain a variety of types of cells.
Term
pneumonitis
Definition
Inflammation of the lungs.
Term
polypoid tumor
Definition
Tumors that grow as projections (resembling a polyp) extending outward from a base.
Term
protein marker tests
Definition
Measure level of specific proteins in the blood or on the surface of tumor cells.
Term
protocol
Definition
Detailed plan for treatment of illness.
Term
proton therapy
Definition
Subatomic particles (protons) produced by a cyclotron deposit absorbed dose of radiation at a focused point in the body.
Term
Radiation
Definition
Energy carried by a stream of particles.
Term
radiocurable tumor
Definition
Tumor cells that are destroyed with radiotherapy.
Term
radionuclide scans
Definition
Radioactive substances (radionuclides) are injected intravenously and scans (images) are taken of organs.
Term
radioresistant tumor
Definition
Tumor cells that require large doses of radiation to be destroyed.
Term
radiosensitive tumor
Definition
Tumor in which radiation can cause death of cells without damage to surrounding tissue.
Term
radiosensitizers
Definition
Drugs that increase the sensitivity of tumor cells to x-rays.
Term
Radiotherapy
Definition
Treatment of tumors using radiation; radiation oncology.
Term
relapse
Definition
A sliding back; recurrence of symptoms of disease.
Term
remission
Definition
To send back; partial or complete disappearance of symptoms of disease.
Term
retinoblastoma
Definition
Tumor of the retina of the eye (embryonic cells); congenital and hereditary tumor; childhood malignancy
Term
ribonucleic acid (RNA)
Definition
Cellular substance that, along with DNA, plays a role in protein synthesis.
Term
sarcoma
Definition
Tumor of flesh tissue (malignant).
Term
scirrhous
Definition
Pertaining to hard, densely packed tumors, overgrown with fibrous tissue.
Term
serous
Definition
Pertaining to a clear fluid (serum) that remains after blood has clotted.
Term
sessile
Definition
Type of polyp that extends from a broad base as opposed to growing on a stalk.
Term
simulation
Definition
Study prior to rad. therapy using CT or MRI to map treatment. It is required for all patients undergoing rad. therapy.
Term
solid tumor
Definition
Tumor composed of a mass of cells.
Term
staging of tumors
Definition
System of evaluating the extent of spread of tumors.
Term
stem cell transplant
Definition
Stem cells (immature blood cells) are harvested from the bloodstream & then reinfused after receiving chemotherapy.
Term
stereotactic radiosurgery
Definition
Single dose of rad. delivered under stereotactic, precise guidance to destroy a vascular abnorm or treat small intracranial tumors.
Term
steroids
Definition
Complex, naturally occurring chemicals, such as hormones, that are used in cancer chemotherapy.
Term
teletherapy
Definition
Radiation therapy using high-energy beams from a distant (tele-) source, such as a linear accelerator or cyclotron
Term
ulcerating tumor
Definition
Growth that has open, exposed surfaces resulting from death of overlying tissue.
Term
verrucous tumor
Definition
Tumor, whose growth pattern, resembles a wart.
Term
viral oncogenes
Definition
Pieces of DNA from viruses that infect a normal cell and cause it to become malignant.
Term
virus
Definition
Infectious agent that reproduces by entering a host cell & using the host’s genetic material to make copies of itself.
Term
xerostomia
Definition
Dryness of the mouth.
Term
alveol/o
Definition
small sac
Term
cac/o
Definition
bad
Term
carcin/o
Definition
cancerous, cancer
Term
cauter/o
Definition
burn, heat
Term
fibr/o
Definition
1.) fibers; 2.) fibrous connective tissue
Term
follicul/o
Definition
small glandular sacs
Term
fung/i
Definition
fungus, mushroom
Term
medull/o
Definition
soft, inner part
Term
mucos/o
Definition
mucous membrane
Term
mut/a
Definition
genetic change
Term
mutagen/o
Definition
causing genetic change
Term
necr/o
Definition
death (of cells or whole body)
Term
onc/o
Definition
tumor
Term
papill/o
Definition
nipple-like
Term
pharmac/o
Definition
chemical, drug
Term
plas/o
Definition
formation, development
Term
ple/o
Definition
many, more
Term
polyp/o
Definition
polyp
Term
prot/o
Definition
first
Term
radi/o
Definition
1.) rays, x-rays; 2.) radius (lower arm - thumb side)
Term
sarc/o
Definition
flesh, connective tissue
Term
scirrh/o
Definition
hard
Term
xer/o
Definition
dry
Term
ana-
Definition
up, apart, backward
Term
apo-
Definition
off, away
Term
brachy-
Definition
short (distance)
Term
epi-
Definition
upon, above
Term
meta-
Definition
1.) change, 2.)beyond
Term
proto-
Definition
first
Term
tele-
Definition
far
Term
-blastoma
Definition
immature tumor
Term
-genesis
Definition
condition of producing, forming
Term
-oma
Definition
tumor, mass, swelling
Term
-plasia
Definition
development, formation, growth
Term
-plasm
Definition
formation, growth
Term
-suppression
Definition
to stop
Term
-therapy
Definition
treatment
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