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Lesson 8: Cardiology/Hematology
147
Medical
Professional
03/02/2009

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Term
RIGHT ATRIUM
Definition
Receives unoxygenated blood from the superior vena cava and the inferior vena cava.
Term
RIGHT VENTRICLE
Definition
Receives unoxygenated blood from the right atrium. Sends it to the lungs to get oxygen.
Term
LEFT ATRIUM
Definition
Receives freshly oxygenated blood from the lungs via the pulmonary veins.
Term
LEFT VENTRICLE
Definition
Receives freshly oxygenated blood from the left atrium. Pumps it out to the body via the aorta.
Term
SYSTOLE
Definition
Contraction of a heart chamber
Term
DIASTOLE
Definition
Relaxation and refilling of a heart chamber
Term
PERICARDIUM
Definition
Protective sac encasing the heart
Term
ANEMIA
Definition
Deficiency of red blood cells
Term
ARRHYTHMIA
Definition
Irregular rhythm of the heartbeat, with or without an abnormally slow or fast rate
Term
ASCITES
Definition
Swelling of the abdomen due to effusion of fluid into the peritoneal cavity
Term
AUSCULTATION OF THE HEART
Definition
The physician notes the quality and loudness of the heart sounds heard through a stethoscope at the four valve areas.
Term
BRADYARRHYTHMIA
Definition
A pulse that is both irregular and abnormally slow
Term
BRADYCARDIA
Definition
Abnormal slowness of the heartbeat (pulse less than 60/min)
Term
BRUIT
Definition
A rough vascular sound, synchronous with the heartbeat, heard on auscultation over a narrowing in an artery.
Term
CARDIOMEGALY
Definition
Enlargement of the heart
Term
CLUBBING
Definition
Club-shaped deformity of fingertips, seen in chronic pulmonary disease.
Term
COR PULMONALE
Definition
Dilatation, hypertrophy, or failure of the right ventricle due to acute or chronic pulmonary disease.
Term
CREPITANT RALE
Definition
A fine crackling rale
Term
DEPENDENT EDEMA
Definition
Edema of the lower extremities, aggravated by the dependent (downward hanging) position
Term
DIAPHORESIS
Definition
Sweating
Term
DYSPNEA
Definition
Shortness of breath
Term
EDEMA
Definition
Swelling due to the presence of fluid in tissue spaces
Term
EFFUSION
Definition
An abnormal accumulation of fluid in a body cavity, such as the pericardium
Term
EJECTION FRACTION (EF)
Definition
The percentage of the blood contained in a ventricle at the end of diastole that is ejected from the heart during the succeeding systole, normally 65% or higher.
Term
EMBOLISM
Definition
Obstruction of a blood vessel by a detached blood clot, air, fat, or injected material
Term
EXUDATE
Definition
A material deposited in or on tissues as a result of inflammation or degeneration and consisting of protein-rich fluid, inflammatory cells, and tissue debris.
Term
FIBRILLATION
Definition
Rapid, random, ineffectual twitching of cardiac muscle, instead of normal regular systolic contractions, due usually to metabolic or coronary vascular disease. Atrial fibrillation can continue for years without serious impairment of health, but ventricular fibrillation is rapidly fatal.
Term
GALLOP RHYTHM
Definition
A cardiac rhythm that simulates the sound of a galloping horse on auscultation, usually due to the presence of a third or fourth heart sound, or both.
Term
HEMOPTYSIS
Definition
Coughing up blood
Term
HEPATOJUGULAR REFLUX
Definition
Increase in jugular venous distension when the examiner applies pressure to the liver
Term
HEPATOMEGALY
Definition
Enlargement of the liver
Term
HYPERTENSION
Definition
Elevation of the blood pressure
Term
HYPERTROPHY, CARDIAC
Definition
Enlargement of a heart chamber due to increase in the thickness of its muscular wall.
Term
HYPOTENSION
Definition
Abnormally low blood pressure
Term
INFARCTION
Definition
Death of tissue due to interruption of its blood supply
Term
ISCHEMIA
Definition
Inadequate blood supply
Term
KEITH-WAGENER-BARKER CHANGES
Definition
Abnormal signs in the retina and retinal vessels due to hypertension and arteriosclerosis, using Roman numerals I through IV.
Term
LUMEN
Definition
The hollow interior of a vessel or other tubular structure
Term
MURMUR
Definition
An abnormal sound,synchronous with the heartbeat, sue to flow of blood through a valve or other passage in the heart. Murmurs are distinguished as to sound quality (harsh, blowing, high-pitched); timing (systolic, mid-systolic, late diastolic); loudness (grade 1 to 6 in one system, 1 to 4 in another); radiation (to apex, carotids, left axilla); where best heard (left sternal border, aortic valve area); effect of position (squatting, standing); and effect of respiratory movements (inspiration, breath-holding).
Term
NOCTURIA
Definition
The need to rise from bed to urinate during the night.
Term
PALPITATIONS
Definition
Various abnormal sensations accompanying heartbeat; unduly rapid heartbeat; noticeably irregular beat; a feeling that some or all heartbeats are unusually strong; a sense of missed beats; or intermittent flip-flop sensations in the heart.
Term
PAROXYSMAL
Definition
Occurring in sudden attacks or seizures (paroxysms).
Term
PAROXYSMAL NOCTURNAL DYSPNEA (PND)
Definition
Sudden attacks of labored breathing awakening a patient from sleep
Term
PERFUSION
Definition
Delivery of oxygen and nutrients to tissues by the circulatory system, with removal of carbon dioxide and other wastes
Term
PERICARDITIS
Definition
Inflammation of the pericardium, the membranous sac surrounding the heart.
Term
PERIPHERAL EDEMA
Definition
Edema of the extremities
Term
PETECHIA (PL. PETECHIAE)
Definition
A very small spot of hemorrhage under the surface of the skin or mucous membrane, usually multiple, due to a local or systemic disorder
Term
PITTING EDEMA
Definition
Edema that retains the mark of the examiner's fingers after release of pressure.
Term
POINT OF MAXIMAL INTENSITY (PMI)
Definition
The point on the chest wall where the impulse of the beating heart is most often distinctly felt by the examiner's fingers
Term
PRECORDIAL
Definition
In front of the heart
Term
PULSE
Definition
The heartbeat, and by extension the rate of heartbeat, as measured at the wrist (radial pulse), the cardiac apex (apical pulse), or elsewhere.
Term
RALE
Definition
A crackling or bubbling sound heard on auscultation of the breath sounds, usually due to fluid in small respiratory passages
Term
RHONCHUS (PL. RHONCHI)
Definition
A whistling or humming sound caused by passage of air through narrowed parts of the respiratory tract
Term
SHOCK (PRECORDIAL)
Definition
An abnormally strong thrust applied to the chest wall by the beating heart, as detected by the examiner's fingers.
Term
SPLITTING
Definition
Seperation of the first or second heart sound, or both, into two distinctly audible components.
Term
STIGMA (PL. STIGMATA)
Definition
A structural or functional peculiarity or abnormality that is characteristic of an ingerited or acquired condition, and may be useful in its diagnosis
Term
SYNCOPE
Definition
Sudden loss of consciousness; fainting
Term
TACHYARRHYTHMIA
Definition
A pulse that is both irregular and abnormaly rapid.
Term
TACHYCARDIA
Definition
Rapid heart rate (over 100/min)
Term
THRILL
Definition
An abnormal sensation felt by the examiner over the heart when blood jets through an anomalous or narrowed orifice
Term
(TUNICA) INTIMA
Definition
The innermost layer or lining of an artery.
Term
VASCULAR
Definition
Pertaining to one or more blood vessels
Term
VASCULITIS
Definition
Inflammation of blood vessels
Term
MYOCARDIAL INFARCTION
Definition
Heart attack
Term
HYPERTENSION
Definition
High blood pressure
Term
ARTERIOSCLEROSIS, ATHEROSCLEROSIS
Definition
Hardening of the arteries
Term
ANGINA PECTORIS
Definition
Chest pain (of cardiac origin)
Term
ANEURYSM RESECTION
Definition
Surgical removal of a segment of vessel that has an abnormal ballooning and threatens to rupture
Term
ARTERIOGRAM
Definition
Injection of radiopaque dye directly into an artery to obtain x-rays of the vessel and its branches
Term
BALLOON ANGIOPLASTY
Definition
Stretching or breaking up atherosclerotic plaques in coronary arteries
Term
BYPASS
Definition
Coronary artery bypass graft
Term
CARDIAC CATHETERIZATION
Definition
A procedure that involves passing a flexible catheter through the femoral artery and into the heart to measure pressures within the heart's chambers. Dye is then injected to show patency or obstruction of the coronary arteries.
Term
CAROTID ENDARTERECTOMY
Definition
Removal of hardened plaque from an obstructed carotid artery
Term
COMMISSUROTOMY
Definition
Surgical enlargement of the aperature of a stenotic heart valve, particularly the mitral, by stretching or cutting
Term
CORONARY ARTERY BYPASS GRAFT (CABG)
Definition
Surgical procedure done to bypass one or more occluded coronary arteries by using a vein graft (often from the leg)
Term
CARDIOPULMONARY RESUSCITATION (CPR)
Definition
The use of external compression of the heart coupled with breathing techniques to revive a victim whose heart and respirations have stopped.
Term
ELECTROCARDIOGRAM (ECG, EKG)
Definition
A tracing of the electrical activity of the heart.
Term
ECHOCARDIOGRAPHY
Definition
A noninvasive diagnostic procedure in which an ultrasonic beam is directed at the heart and the returning echoes are recorded and analyzed; valuable for the measurement of cardiac chambers (wall thickness and cavity volume), assessment of ventricular function, and identification of valvular malfunction.
Term
EXERCISE STRESS TEST
Definition
Test during which the patient exercises on a treadmill to stress the heart and reproduce symptoms of angina and EKG changes
Term
FEMORAL-POPLITEAL BYPASS
Definition
Implantation of a vessel graft (real or artificial) into the femoral and popliteal arteries to bypass one or more blockages
Term
HOLTER MONITORING
Definition
A continously recorded EKG as monitored by a portable EKG machine worn by the patient. This procedure is done on an outpatient basis for 24 hours to detect arrhythmias.
Term
MUGA SCAN (MULTIPLE GATED ACQUISITION SCAN)
Definition
Radiologic procedure in which a radioactive isotope is injected into the arteries with a subsequent scan showing uptake of the isotope by the heart. These radioactive emissions are electronically collected and analyzed by computer, resulting in a series of successive images all taken at the same point in the cardiac cycle. This test is used to assess heart size, shape, and function.
Term
PACEMAKER IMPLANTATION
Definition
Placement of pacemaker electrodes to the heart to correct heart block or control persistant irregular rhythms.
Term
PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY (PTA)
Definition
Procedure used to dilate an occluded artery, usually a coronary artery, by passing a catheter (with a deflated balloon section) to the site of the occlusion and inflating the balloon to compress the obstruction and enlarge the lumen of the vessel.
Term
TREADMILL STRESS TEST
Definition
Exercise stress test (cardiac stress test).
Term
VALVE REPLACEMENT
Definition
Excision and replacement of a valve of the heart because of stenosis or insufficiency
Term
VEIN STRIPPING
Definition
Surgical removal of (usually) the saphenous leg vein and its branches to treat varicose veins
Term
VENIPUNCTURE
Definition
Insertion of a needle into a vein for the purpose of removing blood for testing, or to inject fluids, medicines, or diagnostic materials
Term
SERUM CHOLESTEROL
Definition
A lipid (fatty) material formed in the liver and transported in the blood, which serves as a building block for various hormones and other substances. Elevation of serum cholesterol, which is usually due to an inherited disturbance of lipid metabolism, is associated with increased risk of atherosclerosis.
Term
CREATINE PHOSPHOKINASE (CPK)
Definition
A serum enzyme that can be chemically distinguished into three isoenzymes or fractions: the BB isoenzyme is elevated in cerebral infarction, the MM in muscular dystrophy and muscle crush injury, and MB in myocardial infarction. When seperated in the laboratory by electrophoresis, these isoenzymes appear as distinct bands in a visual display.
Term
HIGH-DENSITY LIPOPROTEINS (HDL)
Definition
Lipid-carrying serum proteins associated with a relatively low risk of cholesterol deposition in arteries.
Term
ISOENZYME
Definition
Any group of enzymes having similar chemical effects but differing in structure and often arising from different sources in the body.
Term
LACTIC DEHYDROGENASE (LDH)
Definition
An isoenzyme. LDH1 is found in heart muscle; levels are increased after myocardial infarction. LDH2 is normally found in higher amounts in the serum than LDH1. When the level of LDH1 surpasses that LDH2, this is called "flipped LDH".
Term
SERUM LIPOPROTEINS
Definition
Serum proteins that bind and transport lipid materials including cholesterol.
Term
LOW-DENSITY LIPOPROTEINS (LDL)
Definition
 Lipid-carrying serum proteins associated with a relatively high risk of cholesterol deposition in arteries.
Term
BAND FORMS, BANDS
Definition
Immature neutrophils whose nuclei appear as bands, in contrast to mature neutrophils whose nuclei are segmented or lobed.
Term
BASOS
Definition
Acceptable brief form for basophils
Term
BLAST FORMS, BLASTS
Definition
Very immature cells, particularly leukocytes, not normally found in peripheral blood but present in acute leukemia
Term
BLEEDING TIME
Definition
The number of minutes it takes for a small incision in the skin, made with a lancet, to stop bleeding. Either the Duke method (puncture of the earlobe) or the Ivy method (puncture of the forearm) may be used.
Term
BLOOD TYPE
Definition
A genetically determined and permanent characteristic of a person's RBCs based on the presence of certain antigens. Two blood type systems of clinical importance are the ABO and the Rh.
Term
BURR CELL
Definition
An abnormal RBC with a jagged contour
Term
CBC
Definition
Complete blood count. A group of blood tests including counts of RBC, WBC, and platelets; a differential count of the various types of WBC; and a determination of hemoglobin and hematocrit
Term
CLOTTING TIME
Definition
The time needed for a clot to form in a tube of freshly drawn blood under standrad conditions. The Lee-White method is the one most often used.
Term
COAGS
Definition
Slang term for coagulation studies.
Term
DIFFERENTIAL WBC COUNT
Definition
A determination of the relative numbers of the six types of WBC normally found in the peripheral blood.When done visually, the technician observes 100 WBC in a stained smear and reports the number of each cell type found as a percent. The six types are segmented neutrophils (PMNs or segs), band neutrophils (bands, representing the immature form), eosinophils (eos), basophils (basos), lymphocytes (lymphs), and monocytes (monos).
Term
EOS
Definition
Brief form for eosinophils
Term
DUKE BLEEDING TIME
Definition
Bleeding time test done by puncture of the earlobe
Term
ERYTHROCYTE
Definition
Mature RBC
Term
FACTORS, BLOOD CLOTTING
Definition

Substances present in the blood that participate in the clotting process:

Factor I fibrinogen

Factor II prothrombin

Factor III tissue thromboplastin

Factor IV calcium

Factor V labile factor (proaccelerin)

Factor VI (term not currently in use)

Factor VII stable factor (proconvertin)

Factor VIII antihemophilic globulin (AHG)

Factor IX Christmas factor

Factor X Stuart-Prower factor

Factor XI plasma thromboplastin antecedent

Factor XII Hageman factor

Factor XIII fibrin-stabalizing factor

Term
GRANULOCYTES
Definition
WBCs with conspicous cytoplasmic granules. Classified as eos, basos, or neutrophils basedo n staining colors.
Term
H&H
Definition
Slang for hemoglobin and hematocrit.
Term
HCT; Hct
Definition
Abbr for hematocrit
Term
HEMATOCRIT
Definition
% of a blood sample that consists of cells. Sample is spun in a centrifuge which quickly drives the cells to the bottom of the tube. The length of the column of cells is expressed as a percent of the total length of the specimen.
Term
HEMATOCRIT, CENTRAL
Definition
A hematocrit value determined by using a blood sample drawn from a central line catheter
Term
HEMOGLOBIN (Hgb, HGB)
Definition
The o2 carrying complex of iron and protein in RBCs. The hemoglobin level is reduced in anemia.
Term
HEMOGLOBIN A1
Definition
Normal adult hemoglobin
Term
HEMOGLOBIN F
Definition
Normal fetal hemoglobin, found also in adults with certain forms of anemia and leukemia
Term
HEMOGLOBIN S
Definition
Abnormal hemo found in the RBCs of people with sickle cell anemia
Term
LEUKOCYTES
Definition
WBCs, including neutrophils, eos, basos, lymphs, and monos
Term
MCH (MEAN CORPUSCULAR HEMOGLOBIN)
Definition
The average weight of hemoglobin per RBC, calculated from the hemoglobin level and the RBC count.
Term
MCHC (MEAN CORPUSCULAR HEMOGLOBIN CONCENTRATION)
Definition
The average concentration of hemoglobin in RBCs, calculated from the homoglobin level and hematocrit
Term
mcL
Definition
Microliters. Used in cell counts to avoid such abbreviations as mm3 or 103 because special characters and superscript numerals do not transmit well electronically.
Term
MCV (MEAN CORPUSCULAR VOLUME)
Definition
The average volume of a RBC, calculated from the hematocrit and the RBC count.
Term
MICROHEMATOCRIT
Definition
A hematocrit measurement performed on a small specimen of blood obtained by finger stick and centrifuged in a capillary tube
Term
MYELOCYTES
Definition
WBCs formed in bone marrow: neutrophils, basos, eos, and monos
Term
NEUTROPHIL, SEGMENTED
Definition
A mature neutrophil with a segmented or lobulated nucleus.
Term
OVALOCYTOSIS
Definition
Abnormal oval shape of RBCs, seen in various congenital disorders of RBC formation, including elliptocytosis
Term
PLATELETS
Definition
Noncellular formed elements in circulating blood, produced in bone marrow and active in blood coagulation
Term
PMNs
Definition
Abbr for Polymorphonuclear leukocytes
Term
POIKILOCYTOSIS
Definition
An abnormally wide variation in the shapes of RBCs as seen in a stained smear
Term
POLYMORPHONUCLEAR LEUKOCYTES (PMNs, POLYS)
Definition
WBCs with segmented or lobulated nuclei. Polys is an acceptable brief form.
Term
PT, PRO TIME (PROTHROMBIN TIME)
Definition
The time required for a clot to form in blood treated with certain reagents. The result may be reported as both a time (in seconds) and a percent of normal prothrombin activity as detected by the same test in a control. The PT is prolonged in deficiency of certain coagulation factors and after treatment with heparin or coumarin anticoagulants
Term
PT/PTT
Definition
Prothrombin time and partial thromboplastin time
Term
PTT (PARTIAL THROMBOPLASTIN TIME)
Definition
The time required for a clot to form in blood treated with certain reagents. Abnormal prolongation of this time occurs in deficiency of various coagulation factors and after treatment with heparin
Term
RBCs
Definition
The most numerous cells of the blood, which carry oxygen from the lungs to the tissues, and carbon dioxide from the tissues to the lungs
Term
RBC COUNT
Definition
The number of RBCs per cubic millimeter of blood, as counted by technician using a microscope or by an electronic cell counter. The count may be reported either as a simple numeral (e.g. 5,300,000/mcL) or as the product of a number less than 10 and 106 (e.g. 5.3 x 106). The count may be dictated simply as 5.3 so the transcriptionist should expand to 5,300,000
Term
RBCs, NUCLEATED
Definition
Immature RBCs, released from the bone marrow before disappearance of their nuclei.
Term
RBC INDICES
Definition
Measures of volume and hemoglobin content of RBCs, derived by calculating from the hemoglobin, hematocrit, and RBC count. The red cell indices are the MCV, MCH, and MCHC.
Term
RETICULOCYTE
Definition
An immature RBC whose cytoplasm contains an irregular network of degenerating nuclear material. An increase in the number of reticulocytes indicates increased RBC production in response to blood loss or hemolysis
Term
SEGS
Definition
Acceptable brief form of segmented neutrophils
Term
SHIFT TO THE LEFT
Definition
An increase in the relative number of immature neutrophils, as detected in a differential WBC. The various types of cells were formerly recorded on forms arranged in columns, the more immature neutrophils being recorded at the extreme left of the form.
Term
SICKLE CELL
Definition
An abnormal RBC found in persons with sickle cell anemia; the cell assumes a sickle or crescent shape at reduced o2 levels.
Term
SICKLING
Definition
an abnormal sickle or crescent shape observed in RBCs on a blood smear
Term
SPHEROCYTOSIS
Definition
Abnormal spherical shape of RBCs as noted in a stained smear of whole blood on microscopic examination
Term
STABS
Definition
Another name for bands (immature neutrophils)
Term
TARGET CELL
Definition
An abnormal RBC with a bull's eye appearance due to flattening of the cell with a prominent spot of hemoglobin in the center.
Term
TRIGLYCERIDES, SERUM
Definition
The level of fat in the serum, usually measured in the fasting state
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