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Medical Microbiology
Bacterial Pathogen Tidbits
23
Biology
Undergraduate 2
10/22/2006

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Term
The most common causes of NEONATAL meningitis
Definition
1. Group B streptococcus (Streptococcus agalactiae);
2. Escherichia coli;
3. Listeria monocytogenes;
Term
The most common cause of pneumonia in adults; the second most common cause of bacterial meningitis in adults; the most common cause of otitis media in children
Definition
PNEUMOCOCCUS (Streptococcus pneumoniae)
Term
The organism that accounts for over 80% of the suppurative diseases:
Definition
Staphylococcus aureus
Term
The only gram-positive bacterium with ENDOTOXIN (LPS)
Definition
Listeria monocytogenes
Term
Gram-negative bacteria without ENDOTOXIN
Definition
Bacteroides fragilis
Term
Bacteria with low virulence but are most often associated with SURGERY
Definition
Bacteroides fragilis
Term
Microbes that cause ATYPICAL PNEUMONIA
Definition
Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia pneumoniae, viruses
Term
The number one cause of bacterial bronchitis & pneumonia in teenagers & young adults
Definition
Mycoplasma pneumoniae
Term
Bacteria that often cause sepsis in immunocompromised patients
Definition
Escherichia coli;
Klebsiella pneumoniae
Term
The three most common causes of diarrhea in the world:
Definition
Campylobacter jejuni;
Enterotoxigenic E. coli;
Rotavirus
Term
Facultative Intracellular Bacteria: (cause systemic infection after phagocytosis)
Definition
Listeria monocytogenes;
Salmonella typhi;
Yersinia pestis;
Francisella tularensis;
Legionella pneumophila;
Mycobacterium spp.;
Brucella spp.;
Term
Bacteria that are obligate intracellular parasites
Definition
Chlamydia;
Chlamydia spp.;
Rickettsias:
(Rickettsia spp.;
Rochalimaea quintana;
Coxiella brunetii;
Bartonella henselae;
Ehrlichia chaffeensis)
Term
Rickettsia
Definition
1. requires an arthropod vector;
2. replicates freely in cytoplasm;
3. tropism for endothelial cells;
4. Most cause rashes, high fevers, and bad headaches
Term
Chlamydia
Definition
1. No arthropod vector;
2. Replicates in endosomes (inclusion bodies);
3. Tropism for columnar epithelium;
4. Different symptoms; infect eyes, genitals, and lungs
Term
Bacteria that commonly cause URETHRITIS
Definition
Neisseria gonorrheae;
Chlamydia trachromatis;
Ureaplasma urealyticum;
Term
The leading cause of preventable blindness in the world
Definition
Chlamydia trachomatis
Term
The two most common causes of STD in the USA
Definition
Chlamydia trachomatis;
Neisseria gonorrheae
Term
DD of STD; Chancroid
Definition
Haemophilus ducreyi;
*painful genital ulcer
*unilateral painful swollen inguinal *lymph nodes, suppurative
Term
DD of STD: Syphilis
Definition
Treponema pallidum
*painless ulcer
*bilateral adenopathy, painless, non-*suppurative
Term
DD of STD: Herpes
Definition
Herpes simmplex virus 1 and 2
*lesions start as vesicles (blisters), *resemble CHANCROID when they break
*painful
*usually accompanied by systemic symptoms (myalgias and fevers)
Term
DD of STD: Lymphogranuloma venereum
Definition
Chlamydia trachomatis;
*painless enlarged inguinal nodes similar to those of chancroid
*development of suppurative inguinal lymph nodes is slower; primary ulcer disappears
before the nodes enlarge
Term
DD of STD: Transplacental Acquired Infections: (ToRCHeS)
Definition
TOxoplasma
Rubella
Cytomegalovirus
HErpes
Syphilis
Term
The RULE OF SIXES for Treponema pallidum infection:
Definition
*6 axial filaments
*6 week incubation
*6 weeks for the ulcer to heal
*6 weeks after the unlcer heals, secondary syphilis develops
*6 weeks for secondary syphilis to resolve
*66% of latents stage patients have resolution (no TERTIARY SYPHILIS)
*6 years to develop tertiary syphilis
SEXual transmission
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