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Med Surg Cancer
Medical Surg Cancer Slides
52
Medical
Graduate
10/10/2012

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Term

What are the characteristics of a malignant tumor?

 

Definition
Irregular shape, invasive, metastasizes, not encapsulated, increased potential for growth, increased recurrence, causes death
Term
What are 3 ways that cancer can spread?
Definition

Metastasis (through lymph and blood vessels), invasion, and seeding

 

Term
What are the 4 causes of cancer?
Definition
1.  Environmental 2. Genetic & familial factors 3.  Hormonal agents 4. Age
Term

Identify what the following Tumor Markers are for:

PSA (normal level?), Ca 125, CA 15-3, CA 19-9

Definition

PSA (Prostate specific antigen)-could also be indicative of infection (normal level <4)

Ca 125 for Ovarian Cancer, CA 15-3 for Breast Cancer, CA 19-9 for Pancrease & Liver.  All are used to monitor treatment

Term
What are some X-rays to test for cancer?
Definition
Standard x-rays, MRI, CT
Term
How does Nuclear Medicine Imaging work?
Definition
Radioactive isotopes gather in areas of high metabolic activities
Term
How does PET scans work?  What is it used for?
Definition
Provide detailed info on blood flow, O2 Uptake, glucose uptake.  Used to look for metastasis and monitor treatment
Term
What is ultrasonography or ultrasound used for?
Definition
Examine abdominal area
Term
What is cytology? & Biopsy?
Definition
Cytology is shedding or scraping cells for lab evaluation.  Biopsy is surgically removing part of tissue.  Biopsy is the most definitive way to determine cancer.
Term
What are the Generalized Cancer Symptoms?
Definition
1.  Unexplained weight loss (10lbs or more w/o dieting) 2. Unexplained fever 3. Fatigue 4. Pain 5. Skin clues
Term
What are the 7 common symptoms of cancer?
Definition
1.  Change in bowel or bladder function 2. sores that do not heal 3. Unusual bleeding or discharge 4. Thickening or a lump 5.  Indigestion or difficulty swallowing 6. Recent change in a wart or mole 7. Nagging cough or hoarseness
Term
What are the 8 steps for cancer prevention?
Definition
1. Eat more fresh vegies 2. Increase fiber intake 3. Reduce intake of fat 4. Stop smoking 5. moderate alcohol intake 6. avoid exposure to sun 7. be physically active
Term
If 40 yrs or older, how often should you get mammogram?
Definition
Yearly
Term
For 40 or older and between 20-39 yrs old, how often should perform clinical breast exam?
Definition
yearly for 40 or older, every 3 yrs if 20-39
Term
When should perform breast self-exam?
Definition
Monthly for all
Term
For 50 or older, how often should get fecal occult blood test, flexible signoidoscopy, double contrast barium enema, and colonoscopy?
Definition
Fecal occult blood test (every year), Flexible signoidoscopy (every 5 yrs), Double-contrast barium enema (every 5 yrs), Colonoscopy (every 10 yrs)
Term
How often should check prostate with Digital rectal exam and PSA test?
Definition
Yearly if 50 or older.  If high risk like blacks, start at age 45
Term
When to check cervis with Pap test & pelvic exam?
Definition
Yearly if 21 or older.  Less frequently after 3 or more normal exams
Term
What are the 3 general treatment options for Cancer?
Definition
1. Cure.  2.  Control.  3.  Palliative
Term
What is the diagnostic staging usef for cancers?
Definition

T- Primary Tumor

N- Lymph node involvement

M- Metastasis is present

Term
What is the grading classification for prognosis?
Definition

I-->caught early with excellent prognosis

IV-->aggressive & less responsive to tx

Term
How can surgery be used as primary treatment?
Definition
Local excision, wide or radical excision
Term
What is prophylactic surgery?
Definition
Performed in between diagnosis.  Want a clear margin.  Incision might be large to achieve a clear margin
Term
What are the 2 additional types of surgery for relieving pain from large mass and restoring body image?
Definition
1.  Palliative surgery 2.  Reconstructive surgery
Term
What are the 3 greatest risks for complication post-op cancer surgery who had chemo or radiation before op?
Definition
1.  Infection, wound healing 2. Pulmonary or renal 3. DVT
Term
How does Radiation Therapy work?
Definition
Break intracellular DNA.  But also destroy DNA of normal cells
Term
What could radiation be used for?
Definition
For cure, control, or palliative.  It is localized and increases with chemotherapy
Term
What are location reactions for the skin by radiation?
Definition
Hairloss, Eurythema (redness), shed skin cells
Term
Reactions of Radiation to Epithelial lining of the GI tract?
Definition
Dry mouth, gastritis, anerexia, N/V/D, Stomatitis
Term

Reaction of external radiation to Bone marrow?

What is the term used to describe a decrease in everything?

Definition

Decrease in RBC, WBC, and Platlets (Thrombopenia), Fatique, more prone to infection.

Pancytopenia- decrease in all areas

Term
What is another radiation option but not as often used?  Benefit?
Definition

Intra-op Radiation

While surgery, give a focused radiation treatment.  Less doses, less ADE

Term
What are the nursing interventions for External Radiation?
Definition
1.  Assess skin & oral mucosa 2.  Gentle oral hygine 3. Good skin care 4. DO NOT USE ointments, lotions, or powerders, avoid sunlight to that area 5. Abd radiation: Antiemetics prior to tx (to alleviate NV)  6. Upper body radaition: expect dry mouth 7. Assist w ADLs
Term

What are the 2 types of internal radiation?

 

Definition
Brachytherapy & Interstitial compartments
Term

What is brachytherapy?

What is it used for?

 

Definition
Implantation is by catheters into body cavities.  Used to treat GYN Cancers
Term
How do you prevent dislodgeing in brachytherapy?
Definition
complete bed rest, log roll pt, foley cath, low residue diet & antidiarrheal meds
Term

What is Interstitial compartments?

What is it used for?

Definition
Temp or permanent consists of needles, seeds, or beads.  Used for breast or prostate cancer
Term
Nursing interventions for Internal Radiation?
Definition
Private room, post notice of radiation, minimize time at beside, Radaition fall out-DO NOT TOUCH, Instruct pt to call and no not touch if dislodges, NO pregnant staff, NO children or preg visitors, Visiting time 30min and keep 6ft distance
Term
What are Cell cycle-specific drugs?
Definition
Chemo agents that destroy cells actively reproducing
Term
Which phase does most chemo target?
Definition
S Phase- DNA Synthesis
Term
Other agents are classified according to what?
Definition
Chemical groups
Term
What are the Common side effects of chemo?
Definition
Alopecia (hair loss), stomatitis (irritation of stomach), and bone marrow supression
Term
What are the dose limiting effects of chemo?
Definition
Hepatotoxicity (liver), Pnemonitis (inflammation of lungs by bacteria), hemorrhagic cystitis, Tubular necrosis (renal problems), cardiotoxicity
Term
What are the cumulative effects of chemo?
Definition
Neurotoxicity
Term
What are some cautions for administration of chemo?
Definition
1.  No pregnant nurses 2. double glove 3. plastic gown  4. No dreaking or eating 5. If spill, block off area and call environmental service 6. dispose all chemo items
Term
What is Extravasation?
Definition
When the medicine gets out of the vessel into the surrounding areas
Term
What should u do in event of extravasation?
Definition
Stop drug.  Apply ice to site.  Physician may aspirate the site & inject neutralizing agent
Term

What is Allogenic Bone Marrow Transplant?

How is it transplanted?

How long does it take the marrow to begin producing RBCs, WBCs, & platelets?

 

Definition
From a selected donor.  Engraftment by IV.  2-4 weeks.  
Term
What is the problem with Allogenic transplant?  How is it prevented?
Definition
GVHD.  Prevented through steriods and immunosuppressant drugs.
Term
What is Autologous Transplant?
Definition
Transplant from self.  Pts' own marrow is harvested, preserved, and treated w. chemo.  Then marrow is re-infused back to the pt.
Term
What is Syngeneic Transplant?
Definition
Transplant from identical twin, perfect match.  
Term
What is nursing care for Bone Marrow Transplant?
Definition
Reverse Isolation:  Private room, Laminar airflow, sterile linen, sterile hygiene equip.  Remove gown AFTER leaving room.  
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