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Definition
Gives a precise description of the drug's chemical composition.
Not usually used unless it is short and sweet.
Example:
the chemical name for tetracycline is:
4-dimethylamino-1,4,4a,5,5a,6,11,12a octhydro0-3,6,10,12,12a pentahydroxy-6-methyl-1,11-dioxo-2-napthacenecarboxamide |
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Definition
| The generic drug name is the non-proprietary name, thought up by the manufacturer and it is the original name. Usually derived from the drug's chemical structure. Also the "Official name" |
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Definition
The official drug name is the same as the generic name of the drug.
Official Drug name = Generic drug name |
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Definition
The Trade name is the Brand name, the name under which a drug is marketed. Copyrighted for 7 years and owned by whoever brought it to market.
A generic drug can have a LOT of trade names.
written as: Panmycin(tetracycline) |
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Definition
Useful to know in order to describe what the drug effects, but not useful in describing how a drug works.
antitussive
analgesic
anticoagulent |
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Definition
Explains how the drug acts. Much more specific than the therapeutic class.
Beta-blockers are all chemically similar.
Sulfa drugs are all chemically similar.
Aceinhibitors very similar.
Pharmacologic class is the BEST way to learn drugs |
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Definition
| An orphan drug may treat a very rare disease or have particularly harmful side-effects. Because of it's risk or lack of demand, or cost to produce, they don't get adopted by any particular drug company. |
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Definition
| All drugs in a class are compared to a Prototype Drug. By learning the prototype drugs in depth, you will have a very good idea of how all the drugs that are compared to it work. |
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Definition
Combination drugs contain more than one active ingredient.
example:
Cozaar is a combo of Losartan + HCTZ (reduces BP) |
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Definition
Pharmacodynamics describes what a drug does to the body.
Does it promote cell function?
Does a drug alter body fluids?
Does it accelerate or slow cell responses? |
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Term
| Receptor Theory of Drug action |
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Definition
The Receptor Theory of Drug action is defined as a lock and key mechanism.
Receptors can be in a cell membrane, a lipid, a specific organ's cells, blood, tissuses, hormones... |
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Term
| Desentization in the Receptor Theory of Drug Action |
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Definition
| Desensatization is a decrease in response after continued stimulation of the receptor. example: Your three-year-old says "mama, mama, mama, mama..." a billion times a day. You hear it at first, but then become desensatized and do not hear it as much. refractoriness is the extreme of this - the receptors no longer respond to the drug. |
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Term
| Refractoriness in drug desensitization |
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Definition
| refractoriness is an extreme of drug desensitization - the receptors no longer respond to the drug at all. |
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Term
| Hyperreactivity in drug sensitization |
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Definition
| hyperreactivity is an extreme of drug sensitization - instead of being desensatized to a drug, receptors become hypersensative or hyperreactive. Sometimes due to the bodies creation of new receptors. Examples: welbutrin, adavan |
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Definition
An agonist is a drug that turns on receptors.
A beta-agonist turns on all beta-receptors. |
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Definition
An antagonist is a drug or food that turns off receptors.
example: Beta-blockers turn of the beta-receptors. |
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Definition
| Selective toxicity is a drugs ability to attack ONLY the enzyme systems found in FOREIGN CELLS. Antibiotics target only foreign cells. (If they attacked enzymes in your own cells, you'd be screwed) |
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Definition
Critical concentration is the amount of drug needed to cause a therapeutic effect. Drugs need to reach their site of action in a suitable form to maintain an appropriate concentration.
650mg of aspirin will help a headache
81mg will "make your platelets less "gooey"
critical concentration of a drug depends on what therapeutic effect you are going for. |
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