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MCMP 407 Final
N/A
281
Chemistry
Professional
12/09/2009

Additional Chemistry Flashcards

 


 

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Term
Muscarine
Definition
Muscarine receptor no medical use, SLUD
Term
ACh
Definition
M+N, intraocular use for miosis, SLUD
Term
Carbachol
Definition
M+N, intraocular use for miosis, glaucoma, SLUD
Term
Pilocarpine
Definition
M, Glaucoma, SLUD
Term
Bethanechol
Definition
M, urinary retention, post operative ileus, SLUD
Term
Chantix
Definition
Partial N agonsist, smoking cessation, SLUD
Term
Edrophonium
Definition
Rev. AChE inh., Myassthenia Gravis, SLUD
Term
Neostigmine
Definition
Reversible AChE, myasthenia gravis, glaucoma, post operative ileus, SLUD
Term
Pyridostigmine
Definition
Rev. AChE inh., Myasthenia gravis, post op ileus, glaucoma, SLUD
Term
Physostigmine
Definition
Reversible AChE, glaucoma, AD, antidote to anticholinergic OD, SLUD
Term
Rivastigmine
Definition
Rev. AChE inh., glaucoma, AD, N&V, anorexia, weight loss
Term
Isofluorophate
Definition
Irr. AChE inh. Glaucoma
Term
Echothiophate
Definition
Irr. AChE inh., glaucoma
Term
Tacrine
Definition
Rev. AChE inh. AD
Term
Donepezil
Definition
Rev. AChE inh, AD
Term
2-PAM
Definition
AChE poisoning antidoe
Term
Memantine
Definition
NDMA rec. antagonist, AD
Term
Reminyl
Definition
Rev. AChE inh., AD
Term
Atropine
Definition
non-selective M antagonist, mydriatic, sedation, tachycardia, dry mouth
Term
Scopolamine
Definition
M ant. sea sickness, ANTI SLUD
Term
Homatropine
Definition
Non-selective M ant. topically to produce cycloplegia, anti-SLUD
Term
Anistotropine
Definition
non-selective M ant. GI spasms and peptic ulcers, anti-slud
Term
Glycopyrrolate
Definition
non-selective M ant. GI spasms and peptic ulcers, anti-SLUD
Term
Topicamide
Definition
M in the eyes, mydriasis, anti SLUD
Term
Ipratropium bromide
Definition
M3 rec ant., asthma of COPD, anti slud
Term
Benztropine
Definition
anti-AChE and antihistamine effects, PD, anti-slud
Term
Procyclidine
Definition
PD, Anti-slud
Term
Tolterodine (detrol)
Definition
M ant. urinary incontinence, anti slud
Term
Diphemanil
Definition
M ant., antispamodic, anti-slud
Term
Benadryl
Definition
M ant., antihistamine, anti-slud
Term
Imipramine
Definition
M. ant, TCA antidepressant, anti-slud
Term
Vesamicol
Definition
Depletes ACh vesicles
Term
Botox
Definition
Inhibits ACh release, old skin
Term
Hemicholinium
Definition
Inhibits uptake of choline
Term
Trimethaphan camphorsulfonate
Definition
Ganglionic (nicotinic) blocker, hypertensive crisis
Term
Mescamylamine
Definition
Ganglionic (nicotinic) blocker, hypertensive crisis
Term
d-tubocurarine
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Pancuronium bromide
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Vecuronium
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Rocuronium
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Atracurium
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Mivacurium
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
Succinyl Choline
Definition
Nic. rec block at motor end plate, muscle relaxation during surgery
Term
l-NE
Definition
alpha, b1, b2 agonist, pressor - dec HR
Term
Epinephrine
Definition
alpha, B1, B2, anaphylaxis, glaucoma, local anestetics (adjunct), inc HR
Term
Phenylephrine
Definition
alpha 1, mydriasis, glaucoma, pressor, nasal decongestant
Term
Naphazoline
Definition
A1 partial agonist, decongestant
Term
Visine
Definition
A1 partial agonist, decongestant
Term
Afrin
Definition
A1 partial agonist, decongestant
Term
Clonidine
Definition
A2 agonist, HTN, sedation, H20 retention, dry mouth
Term
Guanabenz
Definition
A2 agonist, HTN, sedation, H20 retention, dry mouth
Term
Guanfacine
Definition
A2 agonist, HTN, sedation, H20 retention, dry mouth
Term
Methyldopa
Definition
A2 agonist, HTN, sedation, H20 retention, dry mouth
Term
Apraclonidine
Definition
A2 agonist, glaucoma, sedation, H20 retention, dry mouth
Term
Tizanidine
Definition
A2 agonist, muscle spasticity, sedation, H20 retention, dry mouth
Term
Isoproterenol
Definition
non-selective beta agonist, asthma, COPD, cardiostimulant - inc HR
Term
Dopamine
Definition
B1 receptor, critical life threatening situations
Term
Terbutaline
Definition
B2 agonist, asthma, COPD, tocolytic
Term
Metaproterenol
Definition
B2 agonist, asthma, COPD, tachycardia
Term
Albuterol
Definition
B2 agonist, asthma, COPD, tachycardia
Term
Salmeterol
Definition
B2 agonist, asthma, COPD, tachycardia
Term
Formoterol
Definition
B2 agonist, asthma, COPD, tachycardia
Term
Ritodrine
Definition
B2 agonist, tocolytic
Term
Dobutamine
Definition
B1 agonist, acute heart failure, shock; + inotropic effect
Term
Amphetamine
Definition
NET reverser, ADHD, narcolepsy
Term
Ephedrine
Definition
Direct acting agonist, nasal decongestant, CTN: HTN
Term
Pseudoephedrine
Definition
NET reverser, nasal decongestant, CTN: HTN
Term
Cocaine
Definition
DAT blocker, tachycardia
Term
Desipramine
Definition
Transport blocker, depression, ADD
Term
Phenelzine
Definition
MAO inh., depression
Term
Selegiline
Definition
MAO inh. early PD, depression
Term
Phenoxybenzamine
Definition
A1, A2 ant. pheochromocytoma, HTN crisis, orthostatic hypotension, tachycardia
Term
Phentolamine
Definition
A1, A2 ant. phenochromocytoma, HTN crisis, impotence, orthostatic hypotension, tachycardia
Term
Prazosin
Definition
A1 ant. HTN and BPH, reflex tachycardia and orthostatic hypotension
Term
Terazosin
Definition
A1 ant. HTN and BPH, reflex tachycardia and orthostatic hypotension
Term
Doxazonsin
Definition
A1 ant. HTN and BPH, reflex tachycardia and orthostatic hypotension
Term
Ergot alkaloids
Definition
A1, A2 ant, migraines, LSD effect
Term
Yohimbine
Definition
A2 ant. impotence
Term
Propranolol
Definition
B1, B2 ant. HTN, angina, migraine, glaucoma, CHF; bradycardia, AV block; CTN: asthma, COPD
Term
Nadolol
Definition
B1, B2 ant. HTN, angina, migraine, glaucoma, CHF; bradycardia, AV block; CTN: asthma, COPD
Term
Timolol
Definition
B1, B2 ant. HTN, angina, migraine, glaucoma, CHF; bradycardia, AV block; CTN: asthma, COPD
Term
Pindolol
Definition
B1, B2 ant. HTN, angina, migraine, glaucoma, CHF; bradycardia, AV block; CTN: asthma, COPD
Term
Carteolol
Definition
B1, B2 ant. HTN, angina, migraine, glaucoma, CHF; bradycardia, AV block; CTN: asthma, COPD
Term
Toprol
Definition
B1 ant., HTN, angina, CHF, bradycardia, AV block, sedation CTN: asthma, COPD
Term
Bisoprolol
Definition
B1 ant., HTN, angina; bradycardia, AV block, sedation CTN: asthma, COPD
Term
Atenolol
Definition
B1 ant., HTN, angina; bradycardia, AV block, sedation CTN: asthma, COPD
Term
Esmolol
Definition
B1 ant., HTN, angina; bradycardia, AV block, sedation CTN: asthma, COPD
Term
Labetalol
Definition
B1 B2 A1 ant. HTN and HTN crisis, B-blocking prevents reflex tachycardia from A1 block
Term
Carvediolol
Definition
B1, B2, A1 ant. HTN and CHF, B-blocking blocks reflex tach. from A block
Term
alpha-methytrosine
Definition
Inh. NE synthesis, pheochromocytoma, EPS, orthostatic hypotension
Term
Reserpine
Definition
deplete vesicular stores of NE, HTN, may be linked to depression
Term
Bretylium Tosylate
Definition
NE release inhibitor, antiarrhythmic, CTN: pts with AV block
Term
D-ephedrine
Definition
DA, NE, 5-HT releasing agent, decongestant
Term
Methamphetamine
Definition
DA, NE, 5-HT releaser
Term
Amphetamine
Definition
DA, NE, 5-HT releaser, ADHD
Term
Ritalin
Definition
DA/NE reuptake inh., ADHD
Term
Focalin
Definition
DA/NE reuptake inh. ADHD
Term
Strattera
Definition
NET inh. ADHD
Term
Provigil
Definition
Narcolepsy
Term
Phentermine
Definition
NET blocker - appetite suppression
Term
Benzpheramine
Definition
DAT/NET blocker, appetite suppression
Term
Phenmetrazine
Definition
DAT/NET blocker, appetite suppression
Term
Diethylpropion
Definition
DAT/NET blocker, appetite suppression
Term
Meridia
Definition
SERT/NET inh. appetite suppressant
Term
L-DOPA
Definition
PD
Term
Sinemet (levadopa/carbidopa)
Definition
PD, inhibits decarboxylase in periphery
Term
Apomorphine
Definition
D1/D2 ag. PD
Term
Pramipexole
Definition
D2/D3 ag. PD
Term
Requip
Definition
D2/D2 ag. PD
Term
Pergolide
Definition
D2/D3 ag. PD
Term
Bromocriptine
Definition
D2/D3 ag. PD
Term
Rotigotine
Definition
D2/D3 ag. PD
Term
Selegiline
Definition
Irr. MAO inh. PD
Term
Rasagiline
Definition
Irr. MAO inh. PD
Term
Entacapone
Definition
COMT inh. PD
Term
Psilocybin
Definition
5-HT ag. Shrooms
Term
DMT
Definition
5HT-2A
Term
LSD
Definition
5HT2A most potent
Term
Mescaline
Definition
5HT2A
Term
Ectasy
Definition
5HT and DA release
Term
THC
Definition
CB1 ag
Term
PCP
Definition
NMDA blocker
Term
Ketamine
Definition
NMDA blocker
Term
Chloropromazine (Thorazine)
Definition
A1 and 5HT ag. 1st gen antipsychotic, EPS
Term
Promethazine (Phenergan)
Definition
H1 ant. 1st gen antipsychotic
Term
Thioridazine (Mellaril)
Definition
D2 ant. 1st gen antipsychotic
Term
Fluphenazine
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Prochlorperazine
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Perphenazine
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Thiothixene
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Halperiodl
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Molindone
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Pimozide
Definition
D2 ant. 1st gen antipsychotic, EPS
Term
Clozapine
Definition
5-HT2A>D2, atypical antipsychotic, less EPS, treats secondary symptoms
Term
Olanzapine
Definition
5-HT2A>D2, atypical antipsychotic, less EPS, treats secondary symptoms
Term
Loxapine
Definition
5-HT2A>D2, atypical antipsychotic, less EPS, treats secondary symptoms
Term
Seroquel
Definition
5-HT2A>D2, atypical antipsychotic, less EPS, treats secondary symptoms
Term
Risperione
Definition
5-HT2A>D2, atypical antipsychotic, less EPS, treats secondary symptoms
Term
Ziprasidone (Geodon)
Definition
5HT, D2, A1 ant. atypical antipsychotic, less EPS, treats secondary symptoms
Term
Abilify
Definition
5HT2 and D2 partial agonist, antipyschotic
Term
Phenelzine
Definition
non-selective MAOI, antidepressant
Term
Tranylcypromine
Definition
non-selective MAOI, antidepressant
Term
Selegiline
Definition
MAOBI, antidepressant
Term
Moclobemide
Definition
MAOAI, antidepressant
Term
Imipramine
Definition
TCA - NET and SERT inh. antidepressant, can OD - tertiary amine
Term
Amitriptyline
Definition
TCA - NET and SERT inh. antidepressant, can OD - tertiary amine
Term
Doxepin
Definition
TCA - NET and SERT inh. antidepressant, can OD - tertiary amine
Term
Trimipramine
Definition
TCA - NET and SERT inh. antidepressant, can OD - tertiary amine
Term
Clomipramine
Definition
TCA - NET and SERT inh. antidepressant, can OD - tertiary amine
Term
Desipramine
Definition
TCA - NET and SERT inh. antidepressant, can OD - secondary amine
Term
Nortriptyline
Definition
secondary TCA - NET/SERT inh. can OD
Term
Protriptyline
Definition
secondary TCA - NET/SERT inh. can OD
Term
Maprotiline
Definition
secondary TCA - NET/SERT inh. can OD
Term
Fluoxetine (Prozac)
Definition
SSRI - depression, OCD, PTSD
Term
Fluvoxamine (Luvox)
Definition
SSRI - depression, OCD, PTSD
Term
Paroxetine (Paxil)
Definition
SSRI - depression, OCD, PTSD
Term
Sertaline (Zoloft)
Definition
SSRI - depression, OCD, PTSD
Term
Citalopram (Celexa)
Definition
SSRI - depression, OCD, PTSD
Term
Escitalopram (Lexapro)
Definition
SSRI - depression, OCD, PTSD
Term
Amoxapine
Definition
D2 ant, NET inh. anitdepressant
Term
Trazodone
Definition
5HT2 ant. antidepressant
Term
Nefazodone
Definition
5HT2A ant. antidepressant
Term
Bupropion (Wellbutrin)
Definition
DAT>NET=SERT inh. antidepressant
Term
Mirtazapine
Definition
A2 ant, 5HT2, 5HT3, H1, ant. antidepressant
Term
Venlafaxine (Effexor)
Definition
NET and SERT inh. SNRI, GAD, panic, depression
Term
Duloxetine (Cymbalta)
Definition
NET/SERT inh. SNIR; GAD, depression
Term
Reboxetine (Vestra)
Definition
NET inh. Depression, ADHD
Term
Atomoxetine (Straterra)
Definition
NET inh. antidepressant, ADHD
Term
Diazepam (Valium)
Definition
BZD; muscle spasms, sedation
Term
Baclofen (Lioresal)
Definition
GABA-B ag. activates K+ channels, muscle relaxant
Term
Tizanidine
Definition
A2 ag. works in reflex arc, muscle relaxant
Term
Cyclobenzaprine
Definition
Acute muscle spasm, anitmuscarinic properties
Term
Dantrolene
Definition
Reduces release of Ca++ from SR, cerebral palsy, MS, malignant hyperthermia
Term
Succinylchonline
Definition
AChE, Neuromuscular blocks
Term
Mivacurium
Definition
AChE, Neuromuscular blocks
Term
Atracurium
Definition
AChE, Neuromuscular blocks
Term
Vecuronium
Definition
AChE, Neuromuscular blocks
Term
Rocuronium
Definition
AChE, Neuromuscular blocks
Term
Pancuronium
Definition
AChE, Neuromuscular blocks
Term
Ether
Definition
Activate K+, block Na+, disrupt membrane potential; inhaled anesthetics, malignant hyperthermia
Term
Nitrous oxide
Definition
Activate K+, block Na+, disrupt membrane potential; inhaled anesthetics, malignant hyperthermia, FAST
Term
Halothane
Definition
Activate K+, block Na+, disrupt membrane potential; inhaled anesthetics, malignant hyperthermia
Term
Enflurane
Definition
Activate K+, block Na+, disrupt membrane potential; inhaled anesthetics, malignant hyperthermia
Term
Isoflurane
Definition
Activate K+, block Na+, disrupt membrane potential; inhaled anesthetics, malignant hyperthermia
Term
Ketamine
Definition
Block NDMA rec. dissociative anesthesia
Term
Etomidate
Definition
IV anesthetic
Term
Propofol
Definition
GABA channels, rapid onset/recovery
Term
Procain
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Tetracaine
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Benzocaine
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Lidocaine
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Mepivacaine
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Bupivacaine
Definition
Local anesthetic (blocks activated and inactivated Na+ channels)
Term
Chlordiazepoxide
Definition
BZD, metabolites, anxiolytic
Term
Diazepam (Valium)
Definition
BZD, metabolites, anxiolytic
Term
Flurzaepam
Definition
BZD, hypnotic, metabolites
Term
Clorazepate
Definition
BZD, metabolites, anxiolytic
Term
Quazepam
Definition
BZD, hypnotic, metabolites
Term
Alprazolam (Xanax)
Definition
BZD, anxiolytic and anesthetic
Term
Lorazepam
Definition
BZD, metabolites, hypnotic
Term
Clonazepam
Definition
BZD, anticonvulsant
Term
Oxazepam
Definition
BZD, anxiolytic, EtOH withdrawal
Term
Temazepam
Definition
BZD, anxiolytic, EtOH withdrawal
Term
Estrazolam
Definition
BZD, short term hypnotic
Term
Midazolam
Definition
BZD, rapid anesthesia
Term
Triazolam
Definition
BZD, short term hypnotic
Term
Flumazenil
Definition
BZD ant. BZD overdose
Term
Zolpidem (Ambien)
Definition
Z-drug, insomnia, bind A1 subunit of BZ1 site
Term
Zaleplon (Sonata)
Definition
Z-drug, insomnia, bind A1 subunit of BZ1 site
Term
Eszopiclone (Lunesta)
Definition
Z-drug, insomnia, bind A1 subunit of BZ1 site
Term
Phenobarbital
Definition
Barbiturate, anticonvulsant
Term
Mephobarbital
Definition
Barbiturate, anticonvulsant
Term
Amobarbital
Definition
Barbiturate, sedative-hypnotic
Term
Butabarbital
Definition
Barbiturate, sedative-hypnotic
Term
Pentobarbital
Definition
Barbiturate, sedative-hypnotic
Term
Secobarbital
Definition
Barbiturate, sedative-hypnotic
Term
Aprobarbital
Definition
Barbiturate, sedative-hypnotic
Term
Thiopental
Definition
Barbiturate, IV anesthetic
Term
Methohexital
Definition
Barbiturate, IV anesthetic
Term
Thiamylal
Definition
Barbiturate, IV anesthetic
Term
Ramelteon
Definition
MT1 and MT2 ag. works on circardian cycles, sleep
Term
GHB
Definition
GABA-A,B,? narcolepsy
Term
Buspirone
Definition
Partial 5HT1A ag. GAD, socail anxiety
Term
Clomipramine
Definition
Partial SERT inh. TCA
Term
Hydroxyzine
Definition
H1 ant, anxiolytic
Term
Phenytoin
Definition
Na+ blocker, partial/tonic clonic
Term
Fosphenytoin
Definition
Na+ blocker, partial/tonic-clonic
Term
Carbmazepine
Definition
All Sz's except absense, Na+ blocker
Term
Oxcarbamazepine
Definition
Partial, Na+ blocker
Term
Phenobarbital
Definition
Partial/tonic-clonic
Term
Primidone
Definition
All but absence
Term
Gabapentin
Definition
Partial, inc. GABA and Ca++ blocker
Term
Pregablin (Lyrica)
Definition
Neuropathic pain, increase GABA
Term
Vigbatrin (Sabile)
Definition
Adjunct for refractory Sz's, Irr inh. of GABA transaminase
Term
Tiagabine
Definition
Partial/tonic-clonic, Inh. GAT-1
Term
Lacosmaine
Definition
Partial, Na+ blocker
Term
Rufinamine
Definition
Partial and Lennox-Gastaut syndrome
Term
Lamotrigine (Lamictal)
Definition
Partial, Na+ channel blocker
Term
Zonisamide (Zonegram)
Definition
Partial in children
Term
Levetiraceptam (Keppra)
Definition
Partial, GABA and Ca++
Term
Felbamate
Definition
Partial, NDMA ant
Term
Topiramate (Topamax)
Definition
Partial/tonic-clonic, AMAP ant.
Term
Ethosuximide
Definition
Absence, T-type Ca++ blocker
Term
Valproic acid (Depakote)
Definition
Absense, partial, generalized, bipolar; Na+, Ca++, GABA
Term
Valproate
Definition
Tonic/clonic, absence, Na+
Term
Codeine
Definition
Weak analgesic, good antitussive
Term
Morphine
Definition
Sever, acute, chronic pain
Term
Hydromorphone
Definition
Severe pain
Term
Oxymorphone
Definition
Severe pain
Term
Levophanol
Definition
Severe pain
Term
Apomorphine
Definition
Severe pain
Term
Hydrocodone
Definition
Moderate pain
Term
Oxycodone
Definition
Moderate/severe pain
Term
Dextromethorphan
Definition
good antitussive no analgesic
Term
Heroin
Definition
Illegal
Term
Meperidine (Demerol)
Definition
Analgesia Mu agonist
Term
Propoxyphene (Davon)
Definition
Mild/moderate pain, weak Mu agonist
Term
Methadone
Definition
Pain and addiction, Mu ag
Term
Tramadol
Definition
Analgesia, weak Mu ag
Term
Ketorolac (Toradol)
Definition
NSAID, severe pain
Term
Tapentadol (Nucynta)
Definition
Pain, weak Mu ag
Term
Methotrimeprazine
Definition
Pain, increases theshold and creates amnesia
Term
Fentanyl
Definition
Severe pain, Mu agonist
Term
Sufentanil
Definition
Severe pain, Mu agonist
Term
Alfentanil
Definition
Severe pain, Mu agonist
Term
Remifentanil (Ultiva)
Definition
Severe pain, selective Mu agonist
Term
Diphenoxylate with atropine (Lomotil)
Definition
Diarrhea, Mu and Delta ant
Term
Difenoxin with atropine (Motofen)
Definition
Diarrhea, Mu and delta ant
Term
Loperamine (Imodium AD)
Definition
diarrhea, Mu and delta ant
Term
Buprenophine (Buprenex, Subutex)
Definition
Opioid withdrawal, partial Mu agonist, weak kappa ag and delta ant
Term
Butorphanol (Staldol)
Definition
Moderate to severe pain, strong kappa agonist, partial mu agonist
Term
Nalbuphine (Nubain)
Definition
Mod/severe pain K ag mu ant
Term
Pentazocine (Talwin)
Definition
mild/mod pain; kappa ag partial mu ag
Term
Dezocine (Dulgan)
Definition
severe pain, parial mu agonist
Term
Pentazocine with naloxone
Definition
Severe pain
Term
Naloxone
Definition
Opioid OD, mu ant
Term
Naltrexone
Definition
Heroin addiction and EtOH dependence, opioid receptor ant
Term
Nalmefene
Definition
Alcohol dependence, opioid receptor ant
Term
Fomepizole
Definition
Methanol/ethylene glycol poisoning
Term
Disulfiram
Definition
Aldehyde dehydrogenase inh. alcoholism
Term
Acamprosate
Definition
NMDA ant. reduced withdrawal from EtOH
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