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MCAT - Endocrine System
MCAT - Endocrine System
15
Biology
Undergraduate 1
01/26/2007

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Term
ICSH
Definition
ICSH = Interstitial Cell Stimulating Hormone
aka Leutenizing Hormone (LH)
Stimulates interstitial cells between seminiferous tubules to secrete testosterone.
Term
Testosterone
Definition
In the testes, it promotes spermatogenesis
Also promotes secondary sex characteristics in males (deep voice, body hair, enlargement of penis/scrotum)
Term
Adrenal Gland
Definition
An endocrine gland that sits atop each kidney (humans have 2)
Divided into the adrenal corte and adrenal medulla
Term
Adrenal Medulla
Definition
The inner protion of the adrenal gland
It secretes a class of endocrine hormones called catecholamines (epinephrine & norepinephrine)
These hormones ^HR, ^BP, ^Alertness
Their secretion is stimulated by nerve impulses
Term
Adrenal Cortex
Definition
The outer portion of the adrenal glands.
Secrete a class of hormones called corticosteroids.
Corticosteroids are divided into 4 groups:
Mineralocorticoids (ie aldosterone), Glucocorticoids, Anabolic hormones, & sex hormones
Term
Aldosterone
Definition
A mineralocorticoid secreted by the adrenal cortex.
It increases the activity of Na+/K+ pumps primarily at the distal convoluted tube.
This in turn ^ K+ excretion, ^ interstitial [Na+], & ^ H20 conservation
Its secretion is stimulated by ^ extracellular K+, low extracellular Na+, & low fluid levels
Term
Target Hormones of Anterior Pituitary
Definition
Prolactin - stimulates breast development and milk production in females.
Growth Hormone (aka Somatotropin) - influences the growth and development of children and infants
Term
Tropic Hormones of the Anterior Pituitary Gland
Definition
Tropic hormones are those that stimulate other endocrine glands to release their hormones.
Thyroid Stimulating Hormone (TSH) - Governed by the hypothalamus which releases Thyrotropin Releasing Hormone (TRH)
Adrenocorticotropic Hormone (ACTH) - Stimulates adrenocortical secretion of cortisol. It is also governed by the hypothalamus which secretes Corticotropin Releasing Hormone (CRH)
Term
Hormones of the Posterior Pituitary Gland
Definition
Antidiuretic Hormone (ADH) - aka vasopressin)

Oxytocin - secreted during child birth

Both are produced by the hypothalamus & sttored in the posterior pituitary.
Term
Antidiuretic Hormone
Definition
aka ADH, Arganine Vasopressin (AVP)
Produced by the hypothalamus & stored in the posterior pituitary
It induces permeability of collecting ducts in nephrons. As collecting ducts pass through the ^ [salt] of the medulla H2O diffuses out and is retained in the body.
Term
Thyroid Gland
Definition
A flat endocrine gland located in the neck.
It secretes Thyroxine (aka thyroid hormone), Triodothyronine, & Calcitonin
Term
Cretinism
Definition
A condition characterized by stunted mental and physical growth due to a deficiency thyroid hormone in the first 6 months of life.
Term
Calcitonin
Definition
An endocrine hormone produced by the parafollicular cells of the thyroid.

When administered therapeutically, it decreases blood [Ca2+] & inhibits normal bone resorption.
Bone resorption = breakdown of bone by osteoclasts.
Term
Parathyroids
Definition
A set of 4 small glands located posteriorly to the thyroid.
They secrete parathyroid hormone. It has the opposite effects of calcitonin.
^ blood [Ca2+]
^ intestinal uptake of Ca2+
^ uptake of ca@+ in the kidneys
It is secreted in response to low blood [Ca2+]
Term
Pancreatic Hormones
Definition
Insulin and Glucagon (+ others)

Produced by the Islet Cells in the Islet of Langerhans in the pancreas.
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