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MCAT Biology Review
Notecards contain basic biology concepts that will be covered on MCAT
27
Biology
Undergraduate 4
04/30/2013

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Term
Ductus Venosus
Definition
A shunt that allows oxygenated blood to bypass liver; converges with inferior vena cavae; occurs in fetal circulation
Term
Ductus Arteriosus
Definition
A shunt that allows blood to bypass fetal lungs; shunts blood directly from pulmonary artery to the aorta; occurs in fetal circulation
Term
Foramen Ovale
Definition
A shunt that diverts blood from right atrium to left atrium; completely bypasses right ventricle and pulmonary artery to allow systemic circulation
Term
Innate Immunity
Definition
nonspecific immune response; provide first/immediate defense by responding to pathogens in a general way; consists of macrophages, mast cells, granulocytes, dendritic cells, and NT cells
Term
Adaptive Immunity
Definition
specific immune response; comprised of humoral immunity (B-cells) and cell-mediated immunity (T-cells); composed of highly specialized cells that respond to a pathogen in a manner that must be "learned"
Term
Humoral Immunity
Definition
B-cells produce antibodies; involves the production of antibodies(immunoglobulins), which are specific to antigens of invading microbe; part of Adaptive Immunity
Term
B-Cells
Definition
a group of white blood cells known as Lymphocyte; produced in bone marrow and immature ones are housed in spleen/lymph nodes; primary function is to produce antibodies; will proliferate into two daughter cells 1.Plasma cells 2.Memory cells
Term
Plasma Cell
Definition
specialized type of B-cell; produces large amounts of antibodies
Term
Memory Cell
Definition
specialized type of B-cell; stay in lymph nodes for use upon being re-exposed to the same antigen; initial activation of these cells may take 7-10 days (primary response);if same invader infects body again, memory cells will immediately attack (secondary response); may last a lifetime in organism
Term
Cell-Mediated Immunity
Definition
immune response that doesn't involve antibodies but involves the activation of phagocytes and antigen-specific T-cells; helper and regulatory T-cells coordinate immune response while killer T-cells destroy an infected cell
Term
Helper T-Cell
Definition
coordinate immune response by secreting lymphokines (chemicals that recruit other immune cells); provides adequate response to an infection
Term
Suppressor T-Cell
Definition
helps to tone down initial immune response once infection has been adequately contained
Term
Killer T-Cell
Definition
capable of directly killing viral cells by secreting toxic chemicals; can produce memory T-cells
Term
T-Cell
Definition
a group of white blood cells known as Lymphocyte; produced from bone marrow but are housed and mature within the thymus; perform cell-mediated immunity that doesn't involve antigens
Term
Granulocytes
Definition
category of white blood cells that contain granules in cytoplasm; Neutrophils (phagocytes), Eosinophils (kill parasites), Basophils (release histamine)
Term
Agranulocytes
Definition
category of white blood cells that do not contain granules and are mononucleated; lymphocytes (T and B-cells) and monocytes (immature macrophages that will engulf invaders)
Term
Anterior Pituitary
Definition
hormones are released from hypothalamus into hypophyseal portal system (blood stream)and bind to receptors in the anterior pituitary (stimulates the release of hormones from ant. pit.); hormones can be classified as direct or tropic; produces GH, prolactin, ACTH, TSH, LH, FSH
Term
FLAT PEG
Definition
FLAT (Tropic hormones; FSH, LH, ACTH, and Thyroid Hormone) PEG (direct hormones; Prolactin, Endorphins, GH)
Term
Peptide Hormones
Definition
ex: ADH and insulin; hormones made of amino acids; these hormones act as primary messengers that stimulate secondary messenger cascades; derived from long precursor proteins (modified in Golgi); action is immediate but doesn't last long
Term
Steroid Hormones
Definition
derived from cholesterol (nonpolar molecule); can cross cell membrane and bind to intracellular receptors; hormone-receptor binding to DNA (dimerization) promotes transcription of specific genes; not immediate but can have longer lasting effects
Term
Adrenocorticotropic Hormone (ACTH)
Definition
a hormone that is released from anterior pituitary; stimulates the adrenal cortex to synthesize/secrete glucocorticoids
Term
Prolactin
Definition
a hormone that is released from the anterior pituitary; stimulates milk production and secretion
Term
Growth Hormone (GH)
Definition
a hormone that is released form the anterior pituitary; stimulates bone and muscle growth (an active process that requires abundance ATP)
Term
Thyroid-Stimulating Hormone (TSH)
Definition
a hormone produced by the anterior pituitary; stimulates the production of thyroxine (T4) and triiodothyronine (T3); increase cellular respiration, alter glucose/fatty acid utilization, and speed up synthesis/degradation of proteins/fatty acids; set the metabolic rate; regulated by negative feedback
Term
Luteinizing Hormone (LH)
Definition
a hormone produced by the anterior pituitary; stimulates ovulation in females (peak level day 14); stimulates testosterone synthesis in males
Term
Follicle-Stimulating Hormone (FSH)
Definition
a hormone produced by the anterior pituitary; stimulates follicle maturation of a single ovum in females; stimulates spermatogenesis in males
Term
Antidiuretic Hormone (ADH)
Definition
also known as vasopressin; a hormone that is created by hypothalamus but stored in posterior pituitary; stimulates water absorption in the kidney (directly acts on collecting duct to increase water permeability)
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