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MCAT Biology Review 5
The Endocrine System
62
Biology
Not Applicable
07/24/2011

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Term
Endocrine System
Definition

Directly into the fluid.

 

Effects are slower, less direct, and longer lasting than the nervous system.

 

Alter metabolic activities, regulate growth and development, and guide reproduction.

Term
Peptide Hormones
Definition

Derived from peptides.

Manufactured in rough ER.

Water soluble so cannot diffuse through the membrane of the effector.

 

Ant/Post Pituitary Hormones, parathyroid hormone, and pancreatic hormones.

Term
Steroidal Hormones
Definition

Derived from / chemically similar to cholesterol.

From Smooth ER/Mito.

Diffuse through the cell membrane of the effector.

 

glucocorticoids/mineral corticoids, gonadal hormones.

Term
Tyrosine Derivatives
Definition
Thyroid Hormones, epinephrine/norepinephrine.
Term
Hypothalmus
Definition
Controls the release of the anterior petuitary hormones with releasing and inhibitory hormones.
Term
Anterior Pituitary Hormones
Definition

FLATPG

Follicles-Stimulating Hormone FSH

Leutinizing Hormone LH

Adrenocorticotropin ACTH

Thyroid-Stimulating Hormone

Prolactin

Growth Hormone GH

Term
Human Growth Hormone
Definition

Somatotropin

Stimulates growth.

Term
Adrenocorticotropic Hormone
Definition
Stimulates the adrenal cortex to release glucocorticoids using cAMP
Term
Somatostatin
Definition
Inhibits GH
Term
Thyroid Stimulating Hormone
Definition

thyroitropin

Stimulates the thyroid to release T3, T4 using cAMP.

T3 and T4 have a negative feedback effect on TSH release.

Term
FSH
Definition
Term
LH
Definition
Term
Prolactin
Definition
stimulates milk production
Term
Posterior pituitary
Definition
Stimulates the release of Oxytocin and ADH
Term
Oxytocin
Definition
Increases uterine contractions during pregnancy and allows for milk let down.
Term
Antiduiretic Hormone ADH
Definition

Vasopressin

Causes the collecting ducts of the kidney to become permeable to water reducing the amount of urine and concentrating urine.

 

Causes water retention and blood pressure increase.

Term
Adrenal Glands
Definition
Located on top of the kidneys
Term
Adrenal Cortex
Definition

The outside portion of the gland that secretes only steroid hormones.

mineral corticoids and glucocorticoids.

Term
Glucocorticoids
Definition

Increase blood glucose concentration and affect fat and protein metabolism.

 

cortisol

Term
Mineral Corticoids
Definition

Affect the electrolyte balance in the blood stream.

 

Aldosterone

Term
Aldosterone
Definition
steroid mineral corticoid that increases blood pressure by increasing Na+ reabsorption and  K+ secretion.
Term
Cortisol
Definition

A steroid glucocorticoid that increases blood glucose levels by stimulating gluconeogenesis.

 

Stress hormone.

Term
Catecholamines
Definition

Tyrosine derivatives syntesized in the adrenal medulla.

Epinephrine and norepinephrine.

 

Vasoconstrictors of blood vessels and vasoldilators of skeletal muscle.

Stress hormones.

Term
Thyroid
Definition

T3, T4 and Calcitonin production

 

Regulated by TSH

Term
T3 and T4
Definition

Lipid soluble tyrosine derivatives.

 

Increases basal metabolic rates.

Term
Calcitonin
Definition

Large peptide hormone released by thyroid.

 

Slightly decreases blood calcium by decreasing osteoclast activity and number.

Term
Pancreas
Definition

Has endocrine and exocrine funcitons.

 

Secretes insulin and glucagon.

Term
Insulin
Definition

Peptide hormone released by β cells of the pancreas.

 

Lowers blood glucose levels as a result of high carbohydrate or protein levels in the blood.

Term
Glucagon
Definition

A peptide hormone released by α cells of the pancreas.

 

Stimulates glycogenolysis and gluconeogenesis in the liver via cAMP to raise blood glucose levels.

Term
Parathyroid Glands
Definition
4 small glands at the back of the thyroid that release parathyroid hormones.
Term
Parathyroid Hormone, PTH
Definition

Peptide that increases blood calcium.

Increases osteocyte absorption of calcium and phosphate from bone and stimulates proliferation of osteoclasts.

Term
Testes
Definition
The male gonads.
Term
Seminiferous Tubules
Definition

Produces the sperm.

 

Spermatogonia are located here.

Term
Life of a sperm
Definition
Spermatogonia, spermatocyte, spermatids, spermatozoa.
Term
FSH
Definition
Growth of follicles in the female, production of sperm in the male.
Term
LH
Definition
Causes ovulation; stimulates estrogen and testosterone secretion.
Term
Testosterone
Definition

Secondary sex characteristics; closing of epiphyseal plates.

 

Stimulate germ cells to become sperm cells.

Term
Androgen
Definition

Male sex hormone.

Primary is testosterone.

Term
Epididymus
Definition
Location of spermatozoon maturation before ejaculation.
Term
Vas deferns
Definition
Spermatozoa are propelled through here and into the urethra before ejaculation.
Term
Semen
Definition
The complete mixture of spermatozoa and fluid that leaves the penis upon ejaculation.
Term
Oogenesis
Definition

Begins in the ovaries of the fetus.

Arrested as primary oocytes upon birth.

Term
Estradiol
Definition
A form of estrogen steroid that prepares the uterine wall for pregnancy.
Term
Luteal Surge
Definition

The time right before ovulation where estradiol levels rise rapidly causing a dramatic increase in LH secretion.

 

Causes the follicle to burst, releasing the egg - now a secondary oocyte - into the body cavity.

Term
Corpus Luteum
Definition
Secretes estradiol and progesterone throughout pregnancy  or until the luteum degrades into the corpus albicans.
Term
Ovum
Definition
When the oocyte undergoes a second meiotic divison and releases a polar body it becomes an ovum.
Term
Zygote
Definition
When the sperm and the ovum fuse during fertilization they become a zygote.
Term
Cleavage
Definition
Begins in the fillopians tubes on the zygote.
Term
Morula
Definition

A zygote that is composed of 8 or more cells.

The embryo no longer grows during this stage.

Term
Blastocyst
Definition

A morula that develops into a fluid filled sac.

Lodges into the uterus and becomes implanted on about the 5th or 7th day of ovulation.

Term
Human chorionic gonadotropin
Definition
A peptide hormone secreted by the egg upon implantation that prevents the degredation of the corpus luteum and maintains its secretion of estrogen and progesterone.
Term
Placenta
Definition
Formed from the tissue of the egg and the mother and takes over the job of hormone secretion
Term
Determination
Definition
The process by which the cells of the embryo become different from one another and form specialized tissue.
Term
Differentiation
Definition
The specialization that occurs at the end of the development forming a specialized tissue.
Term
Gastrula
Definition
The embryo that has three primary germ layers - ectoderm, mesoderm, endoderm.
Term
Ectoderm
Definition
Develop into the outer coverings of the body and into the cells of the nervous system and sense organs.
Term
Endoderm
Definition
Develop intot he lining of the digestive tract and to much of the liver and pancreas.
Term
mesoderm
Definition
The stuff that lies between the inner and outer coverings of the body - muscles, bones and the rest.
Term
Neurula
Definition
Developed from the gastrula in a process called neurulation.
Term
Neurulation
Definition
The notochord induces the overlying ectoderm to thicken and form the neural plate.
Term
Apoptosis
Definition
Programmed cell death.
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