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MCAT Biology Review 4
The Eukaryotic Cell; The Nervous
48
Biology
Not Applicable
07/19/2011

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Term
Nuclear Envelope (Membrane)
Definition
Double phospholipid bilayer that has large nuclear pores that allows RNA to exist but does not allow DNA to exist.
Term
Phagocytosis
Definition
The cell membrane protrudes outward and envelopes/engulfs particulate matter.
Term
Pinocytosis
Definition
Extracellular fluid is engulfed by small invaginations of the membrane.
Term
Endoplastic Reticulum
Definition
A thick maze of membranous walls separating the cytosol from the ER lumen/cisternal space.
Term
Rough ER
Definition
ER near the nucleus that has many ribosomes attached to it on the cytosolic side where translation occurs to propel protiens into the ER lumen as they are created.
Term
Golgi Apparatus
Definition

This is the series of flattened, membrane bound sacs.

Small transport vesicles bud off from the ER and carry the proteins into the ER lumen as they are created.

 

Packages proteins into vesicles to become secretory vesicles or lysosomes.

Term
Secretory Vesicles
Definition

May contain enzymes, growth factors, or extracellular matrix components that release through exocytosis.

 

This acts as a mechanism of providing the membrane with integral proteins and lipids and a means of membrane expansion.

Term
Lysosomes
Definition
Contain acid hydrolases that can break down every major type of macromolecule within the cell.
Term
Smooth ER
Definition

Site of lipid synthesis including steroids. The smooth ER also helps to detoxify some drugs.

 

Produces triglycerides and stores them in fat droplets.

 

Cholesterol formation and conversion to steroids.

Term
Adipocytes
Definition

Cells containing predominately fat droplets.

Important for energy storage and body temperature regulation.

Term
Peroxisomes
Definition

Vesicles in the cytosol.

They grow by incorporating lipids and proteins from the cytosol.

Self replicate.

Involved in the production and breakdown of hydrogen peroxide.

Inactivate toxic substances

Play a role in the synthesis/breakdown of lipids, and in the metabolism of nitrogenous bases and carbohydrates.

Term
cytoskeleton
Definition

The structure and motility of a cell determined by a network of filaments.

Anchors some membrane proteins and other cellular components within the cell and moves the cell.

Term
mictrotubules
Definition

Large rigid, hollow tubes made from tubulin protein.

Involved in flagella and cilia construction and the spindle apparatus.

Term
microfilaments
Definition

Squeeze the membrane together in phagocytosis and cytokinesis and also are the contractile forces in micrtovilli and muscle.

 

actin is the major component

Term
axoneme
Definition
THe major portion of each flagellum and cilium that contain nine pairs of microtubules forming a circle around two lone microtubules in an arrangement known as 9+2.
Term
Tight Junction
Definition
form watertight seals from cell to cell that can block water, ions, and other molecules from moving around and past cells.
Term
Desmosomes
Definition

Join two cells at a single point attached directly at the cytoskeleton of each.

Found in tissue experiencing alot of stress.

 

(Like spot welding)

Term
Gap Junctions
Definition

Small tunnels connecting cells.

Allow small ions and molecules to move between cells.

Term
Mitochondria
Definition

The powerhouses of hte eukaryotic cells.

Contains own circular DNA that independently replicates.

 

Surrounds by two phospholipid bilayers.

Inner membrane invaginates to form cristae.

Term

Neuronal Communication

vs.

Hormonal Communication

Definition

N: rapid, direct, specific

 

H: slower, spread throughout the body, affect many cells and tissues in many diff ways.

Term
Nervous System
Definition

Allows for rapid and direct communication between specific parts of the body resulting in changes in muscular contractions or glandular secretions.

 

brain, spinal cord, nerves and neural support cells, and certain sense organs.

Term
Neuron
Definition

The functional unit of the nervous system.

 

Consists of many dendrites, a single cell body, and usually one axon with many small branches.

 

Signal moves from the dendrites to the axon hillock where an action potential is generated and moves down the axon to the synapse.

 

Do not depend on insulin to obtain glucose.

Term
Dendrites
Definition
Receive the signal to be transferred in a neuron.
Term
Axon
Definition
Carries the action potential to synapse which passes the signal to another cell.
Term
Action Potential
Definition
The disturbance in the electric field across the membrane of a neuron.
Term
Resting Potential
Definition
Established by an equilibrium between passive diffusion of ions across the membrane and the Na/K pump.
Term
Na+/K+ Pump
Definition

3 positive Na ions out / 2 positive K in

 

This increases the positive charge along the membrane outside the cell relative the inner membrane.

 

The inside thus gets a negative potential relative to the outside (resting potential).

 

Establish resting potential

Term
Voltage Gated Sodium Channels
Definition
Big player in depolarization since it allows Na+ to flow into the cell.
Term
Voltage Gated Potassium Channels
Definition
Major player in repolarization by allowing K+ to flow out of the cell.
Term
Hyperpolarization
Definition
The inside membrane becomes super negatively charged.
Term
Synapse
Definition

Transmit neural impulses from one cell to another chemically or electrically.

 

Slowest process of the nervous system cellular communication.

Term
Chemical Synapse
Definition

Unidirectional synapse.

THe slowest step in the tranfer of a nervous signal.

Can only transfer a signal in one direciton.

Term
Browmian Motion
Definition
The random motion of particles.
Term
Second Messenger System
Definition

Receptors activate another molecule inside the cell to make changes.

Preferred for prolonged changes, i.e. memory.

Term
Myelin
Definition

Electrically insulting sheaths produced by Schwann cells.

 

Increases the rate at which an axon can transmit signals.

 

Myelinated axons appear white (while neuronal appear gray)

Term
Sensory (Afferent) Neurons
Definition

Receive signals from a receptor that interacts with its environment. This then transfers this signal to the neurons.

 

Located dorsally

Term
Interneurons
Definition
Transfer signals from neuron to neuron. 90% of neurons in the body are interneurons.
Term
Motor (efferent) neurons
Definition

Carry signals to a muscle or gland called the effector.

 

Located ventrally

Term
Central Nervous System
Definition

Consists of the interneuron and support tissue within the brain and spinal cord.

 

Function is to integrate nervous signals between sensory and motor neurons.

 

Interneurons

Term
Peripheral Nervous System
Definition

Handles the sensory and motor functions of the nervous system.

 

Divided into the somatic nervous system and the autonomic nervous system

 

Sensory and Motor Neurons

Term
Somatic Nervous Sytem
Definition

Designated to primarily respond to the external environment. Contains sensory and motor function.

Acetylcholine is used as a neurotransmitter.

Voluntary muscle control.

Term
Autonomic Nervous System
Definition

Signals primarily from the viscera.

Involuntary.

Divided into the sympathetic and parasympathetic nervous system.

Term
Sympathetic
Definition
Fight, Flight, Fright or Fuck
Term
Parasympathetic
Definition
Rest and Digest
Term
Acetylcholine
Definition

The neurotransmitter used by all preganglionic neurons in the ANS and postganglionic neurons in the parasypathetic system.

 

Somatic and parasympathetic.

Term
Epinephrine and Norepinehrine
Definition

Post ganglionic neurons of the sympathetic nervous system.

 

Sympathetic Nervous sytem

Term
Cerebrum (Cerebral Cortex)
Definition
Stores memories and processes thoughts
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