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MCAT Biology Review
MCAT Biology Review
64
Biology
Graduate
02/07/2012

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Term
State the purines and the pyrimidines
Definition
Purine: A and G. Pyrimidine: T, C, and U.
Term
G1,G0, S, G2, M
Definition
G1 - Cell enlarges and makes new proteins
G0 - Cell rests and doesn't make any changes
S - Synthesis step where genetic information is replicated
G2 - Quality check stage for organelles and Ct.
M - Mitosis and cytokinesis
Term
Stages of M phase
Definition
Prophase- Chromosomes condense, spindles form.
Metaphase - Chromosomes align
Anaphase - Sister chromatids separate.
Telophase - New nucleus membranes form around the DNA.
Term
Cell division serves what purposes in Eukaryotes and Prokaryotes?
Definition
Eukaryotes do it to make more cells and replace existing ones. Prokaryotes only do it in reproduction via binary fission (asexual reproduction).
Term
How does cell division differ between eukaryotes and prokaryotes?
Definition
Eukaryotes must make new organelles and cytoplasm. Prokaryotes do not have organelles and so do not need to do this.
Term
Centromere
Definition
The area on a chromosome that holds the sister chromatids together.
Term
Chromatids
Definition
Arms on a chromosome.
Term
Chromosome
Definition
Either a diploid or haploid structure of DNA.
Term
Interphase
Definition
The longest period of time in cell division. Comprises G1, S, and G2. Here the genetic information can be seen as chromatin.
Term
Germ cells versus autosomal cells
Definition
Germ cells have 23 chromosomes (haploid, n). E.g. gametes (ova, sperm). Autosomal cells have 46 chromosomes (diploid, 2n). E.g. Blood, skin cells. Germ cells are produced by meiosis, autosomal ones by mitosis.
Term
Centrioles
Definition
Organelles that are outside the nucleus in the centrosome region. Assist in the correct cleavage of chromosomes during mitosis.
Term
Centrosome
Definition
A subcellular location where centrioles are found.
Term
Centriole activity during prophase
Definition
Centrioles migrate to opposite poles of the cell and form spindle fibers (microtubules). These assist as anchors for anaphase.
Term
Asters
Definition
The anchoring point between the DNA and the poles of the cell. Connected by spindle fibers.
Term
Kinetochore fibers
Definition
Fibers that assist the microtubules in the spindle fiber for anaphase.
Term
Metaphase plate
Definition
The area in the cell equidistant to the two poles at which the chromosomes align.
Term
Cells that never undergo division (2).
Definition
Nerve and Muscle cells
Term
How many divisions must a human somatic cell undergo before apoptosis?
Definition
20-50 divisions.
Term
Four types of asexual reproduction
Definition
Budding, binary fission, pathenogenesis, and regeneration.
Term
Why is asexual reproduction less favored than sexual reproduction?
Definition
Asexual reproduction does not allow for genetic variability, which is the basis of which evolution acts upon.
Term
Binary fission (describe, example organism)
Definition
Genetic information replicates, cell grows, invagination and splitting occurs, followed by reformation of the membrane. E.g. Bacteria.
Term
Budding (describe, example organism).
Definition
Equal replication, unequal cytokinesis (less cytoplasm). E.g. Hydra and yeast.
Term
Regeneration (describe, sample organism).
Definition
Mitosis at the site of loss. E.g. lizards, sea stars. Note: Humans can't do this because some cells do not do mitosis.
Term
Pathenogenesis (describe, organism)
Definition
An adult organism develops from an unfertilized egg. E.g. bees, ants, lizards.
Term
Meiosis
Definition
Describes the process of sexual reproduction by the combining of genetic information from gametes (sex cells) that are haploid.
Term
Differences between meiosis and mitosis (result, example)
Definition
Mitosis produces two identical 2n cells. Meiosis produces four, unique n cells. Somatic cells undergo mitosis. Gametocytes undergo meiosis.
Term
Order of meiosis.
Definition
Prophase I, metaphase I, anaphase I, telophase I, metaphase II, anaphase II, telophase II.
Term
Reductional division
Definition
The first part of meiosis comprising the separation of homologous chromosomes.
Term
Equational division
Definition
The second part of meiosis comprising the separation of the sister chromatids from the homologous chromosomes.
Term
Synapsis
Definition
A fundamental difference between mitosis and meiosis. Occurs during prophase I of meiosis where homologous chromosomes (that have already duplicated in interphase) come together and cross over.
Term
Chiasma
Definition
An anatomical point during synapsis where the two chromosomes have crossed over each other when in the tetrad formation.
Term
Disjunction
Definition
Occurs during anaphase I in meiosis, where the tetrads are separated and each chromosome segregates randomly into two intermediate daughter cells.
Term
Interkinesis
Definition
Follows telophase I in meiosis. A short rest period where the chromosomes might partially uncoil.
Term
Nondisjunction
Definition
The failure of homologous chromosomes or sister chromatids to separate during Anaphase I and Anaphase II, respectively. Can result in an individual with more or fewer sets of chromosomes, resulting in disorders such as downs syndome.
Term
Path of sperm?
Definition
Seminiferous tubules
Epididymis
Vas deferens
Ejaculatory duct
(nothing)

Urethra
Penis
Term
Testes (location, function)
Definition
Found in the scrotum (below penis, kept cooler). Make seminiferous tubules and interstitial cells, which make sperm.
Term
Sertoli cells.
Definition
Nourish sperm cells.
Term
Interstitial (Leydig) cells
Definition
Produce sex hormones such as andogen and testosterone.
Term
Semen
Definition
Comprised of sperm and seminal fluid.
Term
Seminal fluid (components, location of components).
Definition
Comprised of seminal fluid produced by seminal vesicles (fructose), prostate gland (alkaline pH), and bulbourethral gland.
Term
Spermatogonia (definition, location)
Definition
Diploid stem cells for sperm. Located in the seminiferous tubules.
Term
Describe the process of spermatogonia to sperm in the context of ploidy.
Definition
Spermatongia are 2n
Meiosis I converts to n spermatocytes
Meiosis II convets to n spermatids, which mature to spermatozoa.
Term
Describe the structure of a spermatozoa.
Definition
It has a head (where the DNA is), and a midpiece which provides motility, and a tail for motility. The head is covered with an acrosome, which is made from material for the golgi apparatus and allows it to penetrate the female ovum.
Term
Gonads differentiate to ? in males and ? in females.
Definition
Testes, ovaries.
Term
In females, sex hormones _ and _ are produced by ?. In males, sex hormones _ and _ are produced by ?.
Definition
Estrogen, progesterone. Ovaries.
Androgens, testosterone. Interstitial cells (Leydig cells)
Term
In female cells, immature ova are nourished by _.
In males, immature sperm are nourished by _.
Definition
Follicles.
Sertoli cells.
Term
Vulva
Definition
External female anatomy.
Term
Males have an _ reproductive tract. Females have _ reproductive tracts.
Definition
Internal and external. (shared with urinary).
Internal. (unshared with urinary).
Term
Peritoneal sac.
Definition
Where mature eggs are deposited in the female reproductive tract. Leads to the fallopian tube (oviduct) and ultimately, the cervix and uterine lining.
Term
Oogenesis
Definition
Primary oocytes (2n, from birth) are released once per month and differentiate into secondary oocytes (one oocyte, one polar body). The secondary oocyte is frozen in metaphase II unless fertilization occurs. Then another polar body and ovum are produced (n).
Term
Zona pellucida
Definition
A layer surrounding an oocyte or ovum (with the corona radiata).
Term
Corona radiata
Definition
A layer surrounding an oocyte and ovum (with the zona pellucida).
Term
Menopause (time, result)
Definition
Around 45-55. Results from no more oocytes being released in response to FSH/LH. This allows these levels to rise rapidly because progestrone and estrogen are no longer produced.
Term
Fertilization (location)
Definition
Occurs most often in the fallopian tubes.
Term
Zygote
Definition
A fused sperm and egg.
Term
Acrosomal apparatus
Definition
A tubelike structure that allows the sperm nucleus to enter the ovum.
Term
Cortical reaction
Definition
The rapid production of calcium that forms a fertilization membrane, preventing fertilization from occurring twice.
Term
Monozygotic twins
Definition
Identical twins produced from the division of the ovum during fertilization. These twins are genetically identical.
Term
Dizygotic twins
Definition
Fraternal twins are produced by two separate ovum being released and fertilized. Not genetically identical.
Term
* Describe the terminology of the progression of sperm (from production to maturation).
Definition
Spermatogonia -> Primary spermatocytes -> 2 haploid secondary spermatocytes -> Immature spermatids -> Spermatozoa.
Term
*Describe the life cycle of a female egg cell with respect to ploidy.
Definition
From birth to just before ovulation, the egg is in prophase of meiosis I as primary oocytes. At ovulation the egg cell is a haploid cell completed meiosis I (secondary oocyte). At fertilization the egg cell completes meiosis II and is a mature ovum. By complete penetration the egg is an ovum.
Term
* At what point in meiosis does the spindle apparatus attach to kinetochore fibers?
Definition
During metaphase. This happens to correctly align the chromosomes on the equatorial plate.
Term
* What is the first location of the egg upon ovulation?
Definition
The egg is released into the abdominal cavity where it is then moved into the fallopian tubes. There is passes to the uterus.
Term
* When does the cell stop being diploid in the meiotic cycle?
Definition
Telophase I. Everything past that point is haploid.
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