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Mammalian Physiology Pharmacology
Pharmacology
34
Biology
Undergraduate 4
10/11/2012

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Cards

Term
Pilocarpine
Definition

cholinomimetic

M and N receptor agonist

fixes glaucoma by relaxing ciliary muscle

Term
duvoid
Definition

Cholinomimetic

M receptor stimulator

helps you pee

contracts detrussor and relaxes sphinctor

Term
Nicotine
Definition

Cholinomimentic

N receptor stimulator at low concentrations

Inhibits skeletal muscles at high concentrations

 

Term
Curare (tubadil)
Definition

Nicotinic 2 receptor antagonist

N2 blocker

skeletal muscle relaxer

Term
succynilcholine SUX (anectine)
Definition

nicotinic 2 receptor antagonist

N2 blocker

skeletal muscle relaxer

Term
trimethaphan
Definition

nicotinic 1 receptor antagonist

use during anesthesia for controlled hypotension

 

Term
Nicotine
Definition

nicotinic 1 receptor antagonist

not used anymore becuase of side effects but it blocks N1

also blocks medulla and ganglion

Term
Atropine
Definition

Muscarinic receptor antagonist

blocks post ganglion neuron parasympathetic sights

in night shade

 

Term
Mydriacyl
Definition

Muscarinic receptor antagonist

blocks post ganglion neuron parasympathetic sights

used in eye exams to dilate pupils

Term
detrol
Definition

Muscarinic receptor antagonist

blocks post ganglion neuron parasympathetic sights

treat bladder instability by blocking parasympathetic on the bladder

 

Term
bentyl
Definition

Muscarinic receptor antagonist

blocks post ganglion neuron parasympathetic sights

treats ibs by slowing intestinal activity

Term
scopolamine
Definition

Muscarinic receptor antagonist

blocks post ganglion neuron parasympathetic sights

inhibits gi track

treats stomach pain and motion sickness

given to astonauts and new mothers

Term
Phygostygmine
Definition

anticholinesterases

inhibit ACHesterase

Term
Mestinon
Definition

anticholinesterase

inhibits ACHesterase

treats myesthemia gravis where immune system attacks N2 receptors

Term

Insecticides

Malathion

Parthion

Definition

war gasses

way too much ach in synapse

muscle spasms and death

Term
demser
Definition

block transmitter synthesis

blocks norep and epinephrine by blocking tyrosine hydroxylase

Term
aldomet
Definition

makes false transmitters

replace L-Dopa with methyldopa

antisympathetic affect

treat hypertension

block alpha 2

Term
Ismelin
Definition

block the release of epi/norepi

treats hypertension

 

Term
serpasil / reserpine
Definition

block norep/ep transport back into storage granules

leaves them in cytoplasm where MAO breaks down

Term

Amphetamines

Ephedrine/dexatrine

Definition

displacement of NT without action potential

enhance all (systemic) sympathetic affects

Term
Levophed
Definition

Andremimetic

alpha agonist that prmotes sympathetic affects

simulates norep

Term
epinephrine
Definition

Andremimetic

alpha agonist that prmotes sympathetic affects

epi-pen

Term
neostephrine
Definition

Andremimetic

alpha agonist that prmotes sympathetic affects

nasaldecongestant and vasoconstriction

Term
clonodine
Definition

alpha 2 agonist

catapress

treats hypertension

lower norep and ep so theres lower BP

Term
isuprel
Definition

beta agonist

binds both beta 1 and 2

treats shock

Term
dobutrex
Definition

beta agnonist

increases heart rate and SV

Term
proventil
Definition

beta agonist

maxair

treats asthma

increases bronchi radii

Term
yupotar
Definition

beta agonist

acts on beta 2

decrease urine contractions and delay labor

Term
aminopress
Definition

alpha antagonist

treats hypertension with vasodilation

alpha 1 blocker

Term
flomax
Definition

alpha antagonist

blocks sympathetic affects on bladder

pee more

Term
cardura
Definition

alpha antagonist

antihypertensive

Term
inderal
Definition

beta blocker - slow HR, SV and BP

treat angina (heart pain)

beta 1 and 2 blocker

bad for asthma

Term

Lopressor

tenarmin

toparol

Definition

beta blocker - slow HR, SV and BP

treat angina (heart pain)

antihypertensives

beta 1 specifics

Term
coreg
Definition

alpha and beta combo

blocks beta 1 beta 2 and alpha 1

great hypertension treatment

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