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macronutrients
functions of minerals and vitamins
12
Biology
Undergraduate 3
04/18/2011

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Term
Magnesium
Definition
-Required for ATP and neuromuscular transmission -Deficiency causes tremors, weakness, cardiac arrythmias & calcium oxalate stones in the kidney -Lowers blood pressure and reduced risk of stroke
Term
Iodine
Definition
  • efficiently absorbed and transported to thyroid gland
  • necesary for thyroxine & triiodothyroine
  • regulates basal metabolic rate in adults and growth in children
  • goiter: enlargement of thyroid
Term
Zinc
Definition
  • required for activity by over 300 metalloenzymes
  • RNA/DNA polymerase
  • structural stability for another 300-700 proteins
  • zinc fingers- DNA binding motif
  • deficiency causes poor wound healing, loss of taste acuity & dermatitis
Term
Zinc in therapy
Definition
  • in Wilson's Disease
  • Zn antagonizes Cu absorption
  • in cancer zinc uptake is reduced
  • —Acute symptoms need copper chelation therapy.
    Maintenance therapy is Zinc
Term
Copper
Definition

—Ceruloplasmin
Iron homeostasis and copper homeostasis
—Cytochrome C oxidase
—Superoxide Dismutase
In conjunction with Zn
—Fatty acid synthesis
—Deficiency causes Anemia, Hypercholesterolemia, Demineralization of Bone, Very rare usually in conjunction with high levels of Zn intake.

Term
Chromium
Definition

—Makes quadruple bonds and quintuple bonds!
—Chromodulin, needed to facilitate insulin activity
—Deficiency – pretty rare
Impaired glucose tolerance
Diabetes causes loss of Cr through the urine.

Term
Selenium
Definition

—Important in selenoproteins
Glutathione Peroxidase removes peroxides in the cytosol
–Complements Vitamin E that works in the membrane
– —Soil is selenium poor in certain parts of the country. Selenium deficiency is avoided by food being marketed from many parts of the country.

Term
Manganese
Definition

Arginase 

Pyruvate carboxylase

Term
Molybdenum
Definition
xanthine oxidase
Term
Fluoride
Definition
strengthens bone and teeth
Term
Boron
Definition
bone formatio 
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