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M-Nin Ch.43 The Immune System
Immunity
19
Biology
Undergraduate 1
03/29/2009

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Term
Phagocytosis
Definition
The ingestion and digestion of bacteria and other foreign substances.
Term
Macrophages
Definition
"Big Eaters", phagocytic cell present in many tissues that functions in innate immunity by destroying microbes and in acquiring immunity as an antigen-presenting cell.
Term
Eosinophils
Definition
A type of white blood cell with low phagocytic activity that is thought to play a role in defense against parasitic worms by releasing enzymes toxic to these invaders.
Term
Natural Killer(NK) Cells
Definition
Help recognize and eliminate certain diseased cells in vertebrates.(Kill by releasing chemicals)
Term
Inflammatory Response
Definition
The changes brought about by signaling molecules released upon injury or infection.
Term
Histamine
Definition
Substance released by mast cells that causes blood vessels to dilate and become more permeable in inflammatory and allergic responses.
Term
T Lymphocytes(T cells)
Definition
Lymphocytes that migrate from the bone marrow to the thymus.(Recognize and inactivate foreign cells).
Term
B Lymphocytes(B cells)
Definition
Lymphocytes that mature in the bone marrow.(Recognize and inactivate foreign cells).
Term
Antigen
Definition
A macromolecule that elicits an immune response by binding to receptors of B cells or T cells.
Term
Antibody
Definition
Protein secreted by plasmas cells(differentiated B cells) that binds to a particular antigen, also called immunoglobulin. All antibody have the same Y-shaped structure and in their monomer form, consist of two identical heavy chains and two identical light chains.
Term
Memory Cells
Definition
Long lived clones of lymphocytes that bear receptors specific for an antigen.
Term
Plasma Cell
Definition
The antibody-secreting effector cell of humoral immunity; arises from antigen-stimulated B cells.
Term
Cytotoxic T Cells
Definition
A type of lymphocyte that, when activated, kills infected cells as well as certain cancer cells and transplanted cells.
Term
Helper T cell
Definition
A type of cell that, when activated, secretes cytokines that promote the response of B cells(humoral response) and cytotoxic T cells(cell-mediated response) to antigens.
Term
Humoral Immunity
Definition
Branch of acquired immunity that involves the activation of B cells and that leads to the production of antibodies, which defend against bacteria and viruses in body fluids.
Term
Cell-mediated Immunity
Definition
Branch of acquired immunity that involves the activation of cytotoxic T cells, which defend against infected cells.
Term
Immunization
Definition
The process of generating a state of immunity by artificial means. Two Types:(Active, Passive)
Term
AIDS
Definition
Specified reduction in the number of T cells and the appearance of characteristic secondary infections.
Term
Interferon
Definition
A protein that has antiviral or immune regulatory functions. (helps activate Macrophages)
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