Term
| What are the lab findings in hypersensitivity pneumonitis? |
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Definition
| increased WBC, increased eos, increased Igs (except IgE), increased CD8 and decreased CD4/CD8 ratio in BAL, increased CD80 and CD86, decreased HSP, annexin and mitogen response |
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Term
| What are the symptoms of usual interstitial pneumonitis/idiopathic pulmonary fibrosis? |
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Definition
| dyspnea/nonproductive cough, diffuse interstitial infiltrates on CXR, honeycombing on HRCT, restricte pattern and low DLCO on PFT |
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Term
| What are the symptoms of acute interstitial pneumonitis/Hamman-Rich syndrome? |
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Definition
| high fever, severe dyspnea over one day, flu-like symptoms, rapid respiratory decompensation |
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Term
| What are the PFT findings for COPD? |
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Definition
FEV1/FVC <70%
FEV1 >80% (mild), 50-80% (moderate), 30-50% (severe), <30% (very severe) |
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Term
What is found in alpha-1 antitrypsin deficiency?
in COPD? |
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Definition
-panlobular emphysema (involves lower lobes)
-centrilobular emphysema (involves upper lobes) |
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