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Lower Extremities
Venous diseases
299
Pathology
Undergraduate 3
04/27/2014

Additional Pathology Flashcards

 


 

Cards

Term

What are among the most

prevalent medical conditions worldwide?

Definition

Acute and chronic venous

diseases and their complications

Term
What is a thrombus?
Definition
A blood clot in a blood vessel
Term
What percentage of thromboemboli arise from the LE veins?
Definition
80%
Term
What percentage of patients die within one hour of a PE?
Definition
10%
Term
What is the mortality rate of PE patients without treatment?
Definition
30%
Term
What is the most devastating complication of DVT?
Definition
Pulmonary Embolism
Term

List the risk factors for DVT

(7 major ones)

Definition
Age, Cancer/cancer therapy,pregnancy, hormone therapy, birth control pills, Surgery and trauma, prolonged immobilization, prior history of DVT, Intravenous access
Term

Definition:

 Elements that are thought to indicate a tendency in an

individual toward the developement of a disease.

Definition
Risk Factors
Term

What surgeries have the highest incidence of DVT?

 What is the rate?

Definition

Hip or knee replacements

 50%

Term
List the Clinical presentations of DVT
Definition

Pain

Swelling

Tenderness

Temperature

Color changes

Venous Ulcers

Term
What type and location of pain is usually associated with DVT?
Definition

Located in the calf,

dull aching pain that may be intense,

may be relieved by elevation

Term
How is swelling associated with DVT usually described?
Definition

Usually in the calf:

Brawny

Spongy

Pitting

Non-compressible

Term
How does the temperature change with DVT?
Definition
Increases due to the increase in the accumulation of blood.
Term
What are the 3 color descriptions of clinical presentation of DVT?
Definition
Erythema, Pallor, cyanosis
Term
How accurate is the diagnosis for DVT by clinical presentation and symptoms?
Definition
50%
Term

What is the percentage of people with silent DVT's?

 

Definition
50%
Term
What is a silent DVT?
Definition
A patient with a DVT that has no signs or symptoms
Term
What is superficial Thrombophlebitis?
Definition
Vein + Clot + Inflammation
Term

T or F

 A SVT is benign and self limiting and doesn't usually progress to a DVT.

Definition

False

benign and self limiting but CAN progress to a DVT

Term

T or F

 Inflammation, pain, tenderness are signs and symptoms of SVT or Thrombophlebitis

Definition
True
Term

What is a sign or symptom of a SVT/Thrombophlebitis?

 A) Redness

B) Palpable cord

C) Pallor

D) A and B

Definition
D) Redness and Palpable cord
Term

T or F

SVT is always associated with a PE

Definition
False, rarely associated with a PE unless located at the SFJ
Term
What is considered direct testing for venous ultrasound?
Definition
Venous duplex imaging
Term
Why is Venous Duplex imaging generally recognized as the Gold standard for venous diagnostic testing?
Definition

Accurate

Reproducible

Safe (non-invasive)

 

Term
Why do we want to keep patients as warm as possible for venous studies?
Definition
To keep veins maximally dilated
Term

T or F

For venous studies the patient should be laying flat on the table.

Definition
False, Supine position in Reverse Trendelenburg
Term

At what degrees should the head be elevated?

 

A) 30-45

B) 5-10

C) 15-20

D) 0

Definition
C) 15-20, without too much bend at the groin
Term
What process is used in transverse to detect a venous thrombus?
Definition

1. locate vein in transverse

2. Intermittent compressions w/enough pressure to coapt vein walls

3. repeat moving distally one probe width at a time

Term
What are the signs of a thrombus in short axis?
Definition

Vein walls will not coapt

May be partially or fully non-compressible

Echogenicity may or may not be present

Term

T or F

 It is okay to do compressions of the vein in long axis.

Definition
False, must be done in transverse.
Term
What is a major characteristic of an Acute Thrombus?
Definition
Vessel dilatation
Term

What type of thrombus - acute or chronic - are the following associated with?

 

Lightly echogenic

Attached firmly

May be floating in the lumen

Contraction of the vein

Spongy texture

Collateral channels

Definition

Acute

Chronic

Acute

Chronic

Acute

Chronic

Term

What type of thrombus - acute or chronic - are the following associated with?

 

Brightly echogenic

Rigid texture

Poorly attached

Vessel Dilatation

Irregular borders

Smooth borders

Definition

Chronic

Chronic

Acute

Acute

Chronic

Acute

Term
What terms are used for normal venous flow patterns?
Definition
Spontaneous and Phasic flow
Term
Define Spontaneous flow
Definition
flow occurs spontaneously in med & lg veins w/the patient at rest, even if the extremity is dependent
Term

T or F

Flow may not be spontaneous in the small veins

Definition
True
Term
Why may flow not be spontaneous in small veins?
Definition
B/C velocity is these vessels is too low to detect (absence of the calf muscle pump)
Term
What does phasic stand for?
Definition
Respirophasic
Term
What does respirophasic (phasic) flow mean?
Definition
The velocity of flow changes in response to respiration.
Term
Name the type of flow[image]
Definition
Spontaneous, Phasic flow
Term

T or F

 During Inspiration thoracic pressure increase and venous flow decreases.

Definition

False

Abdominal pressure Increases

Thoracic pressure decreases

Venous flow decreases

Term

 T or F

 During expiration abdominal pressure decreases and thoracic pressure increases.

 

What happens to venous flow?

Definition

True

 

Abdominal pressure decreases

Thoracic pressure increases

Venous flow increases

 

Term
During the inspiration/expiration phase does the upper extremity do the same or opposite of the lower extremity?
Definition

Opposite

 

Inspiration - UE venous flow increases

Expiration - UE venous flow decreases

Term
When do venous flow patterns change?
Definition
When a thrombus substantially impedes venous return
Term
What type of flow will you see distal to a thrombus?
Definition
Continuous
Term
If you have continous flow in the Mid femoral vein, where is the location of the obstruction?
Definition
Proximal (to heart) in the FV
Term
What may be the only sonographic evidence of venous obstruction?
Definition
Change in flow pattern to continous
Term

Name the type of flow

 

[image]

 

Where is the obstruction?

Definition

Continuous,

 

Proximal to location of probe.

Term
How does a technologist augment venous flow?
Definition
Manual compression of the extremity distal to the site of the probe.
Term
What does distal augmentation prove?
Definition
Confirms patency (openness) of the veins between transducer site and site of compression.
Term
What is absence of distal augment flow on the doppler indicative of?
Definition
Presence of an obstructive thrombus distal to the transducer.
Term
How will the spectral analysis look in a non-obstructive thrombus /collateralized vessel with augmentation?
Definition
Augmentation will be there, just diminished.
Term

What are the different Valvular competency test methods?

 

Definition
Proximal Compression and Valsalva
Term
What does a valvular competency test method prove?
Definition
whether the valves are working to not allow retrograde flow.
Term

T or F

 In normal veins, flow speeds up with compression and diminishes when compression is released.

Definition
False, flow stops w/compression and returns with release
Term
For valvular competency, where does the compression happen in relation to the probe location?
Definition
Proximal
Term
In normal veins what happens to flow during a valsalva manuever?
Definition
forward flow stops with inhalation and breath holding, resumes with exhalation.
Term
If a valve is incompetent, what happens to the flow?
Definition
Retrograde flow occurs when breath is held.
Term

What does the following image show?[image]

 

Definition
Reflux during valsalva, valvular incompetency
Term
When may reflux be normal?
Definition
At valve site.
Term
When does distal compression show valvular incompetency?
Definition
When flow is retrograde at probe site after release of compression.
Term
What are the reflux criteria descriptions?
Definition

Mild

Moderate

Severe

Clinically significant

Term

T or F

 A patient's respiratory variations can make a thorough venous exam difficult or even impossible.

Definition
True
Term

T or F

 It is not necessary to look at a patient's chart to determine if any respiratory problems exist.

Definition
False, should look at chart
Term
What are three different kinds of respiratory variations?
Definition

Cheyne-Stokes

Ventilators

Seizures

Term
What are Cheyne-Stokes Respirations?
Definition
10-20 sec episode of apnea every minute, followed by respirations of increasing depth and frequency. Then repeated.
Term

T or F

Significant hypoxia always occurs in patients with Cheyne-Stokes respirations.

Definition
False, rarely occurs
Term

What type of patient can you often see Cheyne-Stokes respirations?

 A. Coma

B. Athletes

C. CHF

D. Pregnant women

E. A & C

Definition

E. A & C.

CHF patients or Coma patients w/diseased nervous centers of respiration.

Term

T or F

 In most cases, venous compression is possible between ventilator cycles

Definition
True
Term

T or F

The action of the ventilator makes venous compression easier.

Definition

False,

makes venous compression nearly impossible and very difficult

Term

What is the best way to proceed with a venous exam if the patient is having seizures?

A. Strap them down to hold them still

B. Call in some help to hold the patient

C. Do the best, possibly reschedule

Definition
C. Do the best you can, exam may need to be delayed or rescheduled.
Term

T or F

 It is not necessary to document respiratory changes/conditions on the patient history and preliminary report.

Definition
False. Definitely document
Term
What is sensitivity?
Definition
The ability of a test to predict disease.
Term
What is specificity?
Definition
The ability of a test to identify normality.
Term

For venous duplex what is the sensitivity for DVT?

 A. 40-45%

B. 15%

C. 75-81%

D. 93-97%

 

Definition

D. 93-97%

Very reliable

 

Term

For venous duplex, what is the specificity of normal?

 A. 20-23%

B. 95-99%

C. 60-63%

D. 85-90%

Definition
B. 95-99%
Term

What are some differential diagnosis for the signs of DVT that can be identified during the ultrasound exam?

(There are 9 in our notes)

Definition

Popliteal (Baker's cyst)

Hematoma

Post-phlebitic syndrome

Adenopathy

Lymphedema

Cellulitis

CHF

Neuromuscular Problems

Inflammation

Term
Where is the Baker's Cyst located?
Definition
medially located and closely associated with the gastroc muscle
Term
What symptoms do DVT and Baker's Cyst have in common?
Definition
Pain and swelling
Term
What is a Baker's Cyst and what does it cause?
Definition

enlargement of the synovial membrane.

Causes compression of the vein with pain and swelling.

Term

What is an extrinsic compression on the venous system with venous distention, continuous flow that could lead to secondary DVT?

 A. Hematoma

B. Muscle

C. Insufficient valve

Definition
A. hematoma
Term

DVT is no longer present but the damage has been done, leading to venous reflux. What is this?

 

 

Definition
Post-phlebitic syndrome
Term

What differential diagnosis is defined as 'enlargement/swelling of the lymph nodes'?

 

A. Lymphedema

B. Adenopathy

C.Hematoma

D. Ascites

Definition
B. Adenopathy
Term
What is the term for obstruction of the lymphatic system causing excess fluid to accumulate in the interstitial spaces?
Definition
Lymphedema
Term

T or F

 In the absence of detectable lymph node enlargement, specific sonographic findings will point to lymphedema.

Definition

False.

No specific sonographic findings point to lymphedema in the absence of detectable lymph nodes.

 

Term
What can you do to point to lymphedema as a cause of patients swelling?
Definition
Confirm there is not a venous cause of the symptoms.
Term
How does cellulitis differ from lymphedema?
Definition
Cellulitis is inflammation of the cellular or connective tissue as a result of localizing an infection. Lymphedema is accumulation of fluid in the interstitial spaces.
Term

T or F

 Sypmtoms closely mimic that of acute DVT and venous duplex is commonly ordered to differentiate.

Definition
True
Term
In the presence of venous congestion, will the doppler signal be more or less pulsatile than normal?
Definition
More pulsatile
Term
How does CHF become a differential diagnosis for venous disease?
Definition

1. Inability of the heart to pump blood (Rt heart failure) leading to back pressure in the venous system. Shows as tissue edema and leg swelling.

 

2. Fluid overload, from possible renal failure

Term

What type of flow is this?

[image]

Definition
Pulsatile venous flow
Term
What does pulsatile flow in the SFV suggest?
Definition
Elevated Right heart pressures
Term

T or F

 CHF is associated with unilateral symptoms and SOB.

Definition
False. Associated with bilateral symptoms and SOB
Term

T or F

 Fluid accumulation associated with CHF can be visualized in the subcutaneous areas.

Definition
True
Term

T or F

Venous duplex is not often ordered to rule out DVT for CHF patients.

Definition
False. Frequently ordered though < 5% actually have DVT.
Term
Why are neuromuscular problems a differential diagnosis?
Definition
Muscle strain causes generalized leg discomfort.
Term
Why is generalized inflammation a differential diagnosis for DVT?
Definition
Joints and tissues cause swelling and pain.
Term

T or F

DVTs can originate anywhere in the venous system

Definition
True
Term

Where do DVT's initially originate?

A. Arteries

B. Lungs

C. Vein sinusoids (behind valve cusps)

D. Capillaries

Definition
C. Vein sinusoids (behind valve cusps)
Term

What locations in the legs are thought to be the most common origin site for LE DVT?

A. Soleal Sinuses

B. Gastrocnemius vessels

C. GSV

D. SSV

Definition
A. Soleal Sinuses
Term
What are the 4 classifications of DVT?
Definition

Non-obstructive

Obstructive

Acute Venous Obstruction

Chronic Obstruction

Term

Define Insufficiency

 

Relate it to venous insufficiency

Definition

The condition of being inadequate for a given purpose.

 

VI: an impaired or inadequate ability to move blood out of the leg.

Term

Define Incompetence

 

Relate it to valvular incompetence

Definition

Inadequate ability to perform the function or action normal to an organ or part.

 

VI: Inadequate ability of a vein valve to perform the function of one way flow.

Term

Define reflux

 

Relate it to venous reflux

Definition

A return of backward flow

 

VR: leakage or significant backward venous flow.

Term

Which of the following are not related to a non-obstructive DVT?

 A. Clot resolves & causes minimal vein damage

B. Recanalization may occur to allow flow

C. May extend to become obstructive

D. Free Floater

Definition
B. Recanalization may occur to allow flow in obstructive DVT
Term

T or F

A non-obstructive clot can become an obstructive clot.

Definition
True
Term

Which is not associated with obstructive DVT?

A. Free Floater

B. Clot attaches to wall

C. Over time clot contracts pulling vein in

D. Vein valves are often destroyed and non-functional

Definition
A. Free floater
Term

T or F

 In Acute venous obstruction, symptoms may not appear because of sufficient collaterals.

Definition
True
Term

Why might the symptoms associated with acute venous obstruction diminish with time?

 

Definition

1. The clot undergoes fibrinolysis

2. The clot undergoes organization and becomes smaller (clot retraction)

Term
List the complications of Acute DVT
Definition

Venous claudication

Phlegmasia alba dolens

Phlegmasia cerulea dolens

Free floating tail embolism

Term

 

What is the term for the following definition?

 

When a patient exercises and oxygenated blood is not available to the muscles, due to poor venous drainage, there is pain.

Definition
Venous claudication
Term
Pallor or whiteness may be secondary to arterial spasm in what type of Acute DVT?
Definition
Phlegmasia alba dolens
Term
What does the leg look like with phlegmasia alba dolens?
Definition
A swollen pale extremity (milk or white leg)
Term

Where is the acute DVT usually located when a patient presents with phlegmasia alba dolens?

 

Definition
Iliofemoral DVT
Term
What color is the leg when a patient presents with phlegmasia cerulea dolens?
Definition
Severe cyanosis
Term

T or F

 Acute DVT leading to phlegmasia cerulea dolens is mild.

Definition
False, so severe it impedes arterial inflow.
Term
How does the patient present with Phlegmasia cerulea dolens?
Definition
Massively swollen leg with severe cyanosis and intense pain.
Term

T or F

 Phlegmasia cerulea dolens can lead to venous induced gangrene

Definition
True
Term
What are two outcomes if a free floating tail embolizes?
Definition

Systemic Arterial Hypoxemia

&

Pulmonary Embolism

Term

T or F

 A pulmonary embolism is not life threatening.

Definition
False, it is life-threatening
Term

What percentage of above knee thrombus end in Pulmonary embolisms?

 A. 5%

B. 50%

C. 70%

D. 99%

 

Definition
B. 50%
Term

T or F

 There is a direct relationship between the size of the embolus and the percutaneous O2 levels.

Definition
False, there is an inverse relationship.
Term

What complication of Acute DVT are the following related to?

1. Blood fails to reach the pulmonary capillary bed

2. Oxygenation is impaired

3. Decreased percutaneous O2 levels

Definition
Systemic Arterial Hypoxemia
Term
What is the most common symptom of PE?
Definition
Dyspnea or Shortness of Breath (SOB)
Term

Which of the following is not a symptom of PE?

A. Pleuritic pain

B.Tachypnea

C. Apprehension and Anxiety

D. Fainting

E. Non-productive cough

Definition
D. fainting
Term

What is the complication of a PE?

 

What is this due to?

Definition

Pulmonary Hypertension

 

Due to increased resistance in the pulonary circuit, leading to higher workload on the right heart and increased venous back pressure.

Term

T or F

 A massive emboli may cause sudden death when the larger pulmonary arteries are involved.

Definition
True
Term
What are the different methods of diagnosing PE?
Definition

Chest X-Ray

VQ Scan - Nuc Med (gas or injection)

Pulmonary Angiography - contrast + x-ray

Term
What is it called when an acute DVT is not lysed and adheres to the vein wall?
Definition
Chronic DVT
Term
What are the descriptions of postphlebitic syndrome?
Definition

Vein lumen is small and flow is directed toward the center,

Thrombus adheres to the wall and becomes fibroelastic.

Pattern of resolution varies.

Term

What are the clinical manifestations of chronic DVT?

 

 

Definition

Postphlebitic Syndrome

Chronic Venous insufficiency

Swelling

Venous dilation

Leg pain

Hyperpigmentation

Venous stasis ulcers

Term
Why do veins have abnormally high pressures in deep veins with chronic venous insufficiency?
Definition
There is an inadequate ability to move blood out of the leg that especially causes high venous pressures when a patient stands or walks.
Term
Where does the swelling usually start on the leg with a DVT?
Definition
Ankle
Term
When swelling goes down with elevation what does this prove?
Definition
Venous insufficiency (Chronic DVT)
Term
What type of edema is usually associated with Chronic DVT swelling?
Definition
Pitting
Term

T or F

 With progression of the venous insufficiency, the superficial veins do not change.

Definition
False, superficial veins become more dilated and tortuous.
Term

How is leg pain usually described with chronic DVT?

 

Upon standing?

Definition

Dull Ache with heaviness.

 

pain or leg fullness upon standing

Term

Describe the process of hyperpigmentation.

 

What kind of dermatitis is this associated with?

Definition

High pressure in venous system forces RBC out of capillaries and into interstitial spaces. Dying RBC metabolize the iron ion which causes the brown discoloration.

 

Scaling dermatitis

Term
How are Venous stasis ulcers formed?
Definition

Caused by postphlebitic syndrome,

high capillary pressure forces fibrinogen into interstitial tissue where it becomes fibrin.

Fibrin prevents proper nutrition and oxygenation of tissues.

Term
Where do ulcers usually form?
Definition
Medial aspect of the ankle. the "gaiter" zone.
Term

Describe a venous ulcer.

 

Dry or wet?

Painful or not?

Regular or irregular borders?

Granulation bed?

Inflammation?

Definition

Usually weepy and bleed easily (wet)

Very painful

Irregular borders w/moist granulating base

surrounded by a zone of inflammation.

Term
What vessels often feed ulcers?
Definition
Perforators
Term
What does the D-Dimer test detect in the blood to assist with the diagnosis of acute DVT?
Definition
plasmin-lysed fibrin particles
Term

When is the D-Dimer test used?

 

A. When testing for anemia

B. Patients present w/positive venous signs and symptoms

C. To visualize the deep veins of the legs

D. To prove insufficiency

Definition
B.
Term

What are the pros of using the D-Dimer test?

A. Minimally invasive

B. Relatively inexpensive

C. Performed quickly

D. All of the above

Definition
D
Term
Where will the patient be referred to if the D-Dimer test is positive?
Definition
Vascular Lab
Term

Which of these 4 is not another name for Venography?

 A. Phlebography

B. Contrast venography

C. Ultrasound Angiography

D. Ascending venography

Definition

C.

 

Term

T or F

Contrast Venography is not an invasive method to detect DVT?

Definition
False, it is an invasive method to detect DVT by use of a contrast media and radiography.
Term

T or F

 Contrast Venography was replaced by Venous Duplex due to the higher sensitivity and specificity rates and non-invasive nature.

Definition
True
Term
Why is contrast venography used still today?
Definition
In cases of high clinical suspicion for thrombosis but negative on non-invasive test.
Term

T or F

 During contrast venography the patient stands on the affected foot while contrast media is injected into a superficial vein of the foot and progress of the dye is monitored by image intensified fluoroscopy

Definition
False, patient stands on unaffected (contralateral) foot.
Term
What is used to drive contrast into the deep system during venography?
Definition
tourniquet
Term

What images are taken with the venography table at 45-60o?

A. Frontal poplitieal

B. Frontal Thigh

C. AP Oblique calf

D. AP lateral calf

E. Both C & D

Definition
E. Both C & D
Term

What venography views are taken with the table tilted at 30-45o?

A. Lateral popliteal

B. Frontal popliteal

C. Oblique popliteal

D. Frontal Thigh

E. Both B & C

Definition
E. Both B & C
Term

What venography views are taken with the table tilted at 15-30o?

A. Frontal Thigh

B. Frontal popliteal

C. Oblique popliteal

D. Lateral popliteal

 

 

Definition
A. Frontal thigh
Term

What view is taken while the table is horizontal and the patient performs the valsalva maneuver?

A. Oblique Thigh

B. Iliocaval

C. Frontal popliteal

D. Frontal Calf

Definition
B. Iliocaval
Term

T or F

 More than one injection of contrast is possible to focus on problem areas.

Definition
True
Term
How is the contrast removed when contrast venography is finished?
Definition
Patient placed in Trendelenburg position and performs calf raises. Heparin saline is used to help clear contrast from veins.
Term

T or F

Results of a contrast venography will visualize all deep and superficial veins of the leg that are in continuity with the injections site.

Definition
False, only the deep veins of the leg are in continuity with the injection site.
Term

T or F

PFV is not visualize beyond the first competent valve in contrast venography.

Definition
True
Term

T or F

The Internal Iliac Vein is not visualized.

Definition
True
Term

T or F

 Normal veins appear rough and tortuous in the venous contrast images.

Definition
False, normal veins are smooth walled and straight or slightly curved; display well defined valves.
Term

T or F

Veins of the calves, because they are paired, must be visualized from a variety of views when interpreting contrast venography.

Definition
True
Term

Presence of a constant filling deficit demonstrable on more than one view is a  ___________ result in contrast venography of an intraluminal clot.

A. Positive

B. Negative

Definition
A. Positive
Term

How does the contrast look in venography when there is a freely floating, partially attached thrombus?

A. Stops abruptly

B. Looks central or eccentric

C. Terminates as a tail extending toward the head

D. presence of collateral veins w/contrast

D. B & C

E. All of the above

Definition
D. B & C
Term

How does the contrast look in venography when there is a DVT?

 A. Stops abruptly

B. Looks central or eccentric

C. Terminates as a tail extending toward the head

D. presence of collateral veins w/contrast

D. A & D

E. All of the above

Definition
D. A & D
Term
Positive results of venography that show a lack of contrast in the entire deep system are suggestive of __ _________ ____.
Definition
a massive DVT
Term

If positive results of contrast venography are suggestive of a massive DVT, what is the next step?

A. Remove tourniquet to determine collateral flow

B. Surgery

C. Duplex ultrasound

D. Nothing

Definition
A. Remove tourniquet to determine presence/lack of collateral flow.
Term

T or F

Contrast venography is unsurpassed in its "map" of the venous system when performed and interpreted properly and interpretation of the contrast venography always has high diagnostic accuracy.

Definition
False, in 5-15% of patients it is uninterpretable due to poor technique.
Term

What are the 2 pitfalls of venography?

A. Poorly mixed contrast/blood, looks like filling defect

B. Great map images of the deep venous system

C. hard on the patient

D. Inexperience and poor technique

E. Both A & D

Definition
E. Both A & D
Term

What is descending venography used to determine?

 

Definition
Valvular incompetence
Term

What is the nuclear medicine test called using IV injection of 99Technetium?

 

 

Definition
AcuTect
Term
Where are tourniquets placed for the AcuTect test?
Definition
Ankle, knee, & thigh
Term

When are pictures taken for the AcuTect test?

A. 5 min after injection

B. 30 min after injection

C. 1 hour after injection

D. Several hours after injection

E. B & D

Definition
E. B & D
Term

What are the AcuTect limitations?

 A. Pregnancy

B. Breast feeding

C. Chronic clot

D. All of the above

Definition
D. All of the above
Term
What type of clot, acute or chronic, does the AcuTect test appear to not detect?
Definition
Chronic
Term

Normal Veins are not _________ ________; are able to accomodate __________ blood volume and have _______ outflow.

A. completely filled, decreased, rapid

B. ever filled, increased, slow

C. completely filled, increased, rapid

D. always empty, increased, slow

Definition
C. completely filled, increased, rapid
Term

With a venous obstruction pressure is ________, volume is _________, capacitance is ______, and emptying is _________.

A. elevated, increased, maximal, slower

B. elevated, decreased, maximal, rapid

C. lowered, increased, minimal, slower

D. lowered, decreased, minimal, rapid

Definition
A. elevated, increased, maximal, slower
Term

What are 3 methods of venous insufficiency?

 

 

Definition

Congenital

Passive Dilation

Vavle dysfunction from direct damage

Term
What are 4 valve pathologies from post-thrombotic damage?
Definition

Destroyed valve cusp

Perforated cusp

"Frozen" and thickened valve cusp

Adherent valve cusp w/thickening

Term
What are some congenital anomalies of the venous conduit and valve structure?
Definition

Tricuspid vavle

Avalvular duplication conduit

duplication conduit w/refluxive valves

Duplication of the valve with an intervening septum

Duplication of the valve w/o an intervening septum

Refluxive monocuspid valve

Term
Describe the process of passive dilation in venous insufficiency.
Definition
Vein wall dilates from increased pressure & volume, dilation pulls collagenous ring that supports valve, leaflets lose ability to coapt & prevent reflux.
Term
What type of vein is described as abnormally dilated and tortuous superficial veins due to chronically increased pressures and volumes?
Definition
Varicose Vein
Term
What is the mechanism for Primary varicose veins?
Definition
Descending valvular incompetency
Term

What mechanism is described below?

 

Physiological changes associated with DVT in the deep veins destroying valves and allowing blood to flow downward through incompetent valves.

Definition
Mechanism is for Secondary varicose vein formation
Term

T or F

 Most varicose veins are of secondary cause.

Definition
False, they are of primary cause.
Term

T or F

 Primary varicose veins demonstrate stasis and are at risk for development of superficial thrombophlebitis.

Definition
True
Term

T or F

Many cases of SVT develop on a background of secondary disease.

Definition
False, primary.
Term
What 3 perforators feed the gaiter zone?
Definition
Cockett I, II, & III
Term

What vein connects the SSV and the GSV?

 

What is another name it is known as?

Definition

Vein of Giacomini

 

AKA: Intersaphenous V.

Term
What 2 types of plethysmography are used today to detect venous reflux due to valvular incompetence?
Definition
Photo (PPG) & Air (APG)
Term
What does photoplethysmography (PPG) measure?
Definition
changes in blood content of the skin
Term

T or F

The strength of reflected signal in PPG is proportional to the amount of RBC's in circulation.

Definition
True
Term

T or F

 Photoplethysmography is a true plethysmographic technique measuring volume, not reflection.

Definition
False, it is not a true plethysmographic technique. It measures reflection, not volume
Term
For the PPG test how is the patient positioned and where is the PPG probe placed on the leg?
Definition
Patient is seated w/legs in dependent, non-weight bearing position. Probe is taped to skin in gaiter zone above medial malleolus.
Term
How is baseline measured for PPG?
Definition
Patient at rest w/legs in a dependent, non-weight bearing position to fill the lower extremity.
Term

In PPG, after baseline is established, what is the patient then instructed to do?

A. Flex arms

B. Flex thighs

C. Swing legs back and forth

D. Dorsiflexion 5 times

Definition
D. Dorsiflexion 5 times.
Term

Dorsiflexion activates the _____ and _______ the volume of blood in the patient's leg?

A. Immune response, decreases

B. calf muscle pump, increases

C. arterial flow, reduces

D. Calf muscle pump, reduces

Definition
D. calf muscle pump, reduces
Term

What does the following define?

 

Number of seconds required for post exercise recovery curve to achieve stable baseline after dorsiflexion.

Definition
Venous return time (VRT)
Term

What venous recovery time indicates valve incompetence (reflux)?

A. < 23 sec

B. > 23 sec

C. < 46 sec

D. none of the above

 

Definition
A. < 23 sec
Term

T or F

 During a PPG test a tourniquet can be applied to distinguish between deep and superficial incompetence.

Definition
True
Term

If VRT is abnormal without tourniquet but normal with it, what does this indicate?

A. Superficial valves are competent

B. Deep valves is incompetent

C. Superficial valves are incompetent

D. Superficial valves are normal

Definition
C. Superficial valves are incompetent
Term

If VRT is < 23 sec w/and w/o tourniquet proves what?

A. All systems are normal

B. Deep system is normal, superficial is incompetent

C. Deep = incompetent, superficial incompetency cannot be determined

D. Deep and superficial systems are incompetent

Definition
C. Deep system is incompetent, superficial cannot be determined to be incompetent or competent.
Term

What classification of venous insufficiency manifests as mild ache and swelling with a VRT of 20-23 sec?

 A. Grade III

B. Grade I

C. Grade II

Definition
B. Grade 1
Term

What classification of venous insufficiency manifests as mod-severe swelling, leg heaviness, & skin pigmentatin with a VRT of 10-20 sec?

A. Grade III

B. Grade I

C. Grade II

Definition
C. Grade II
Term

What classification of venous insufficiency manifests as severe swelling & skin discoloration, leg pain, & ulcer with a VRT of < 10 sec?

 A. Grade III

B. Grade I

C. Grade II

Definition
A. Grade III
Term

What are the disadvantages of PPG?

A. Improper placement of sensor, thick skin, non-intact skin.

B. Too much patient movement

C. muscle contraction artifact

D. specific incompetent valves are identified

Definition
A. improper placement of sensor, thick skin (prevents penetration of infrared light), non-intact skin (sensor must be placed on intact skin)
Term

What type of test does the following describe?

 

A quantitative method of evaluating lower extremity volume changes in relation to gravity and exercise.

Definition
Air Plethysmography (APG)
Term

What are the 4 calibrated way to measure lower extremity volume changes?

 

Definition

Calf venous volume

Rate at which calf venous volume fills

Calf muscle pump effectiveness

Ambulatory venous pressure

Term

What is the first position the patient is placed in for APG and what is recorded?

 A. Standing, venous baseline

B. Supine w/leg at 45o, max venous emptying

C. Calf raises, venous volume

D. Supine w/leg straight, venous refill time

Definition
B. Supine w/leg at 45o, max venous emptying (low venous volume)
Term

When patient is quickly brought from supine to standing position (w/weight on opposite limb) what is being recorded?

 A. Venous refill time

B. Venous outflow

C. functional venous volume

D. none of the above

Definition
C. functional venous volume (high baseline)
Term

What is used to get venous filling index (VFI)?

A. 90%VV/VFT90%

B. VV/VFT

C. (VV/VFT)x100%

D. None of the above

Definition
A. 90%VV/VFT90%
Term

What venous filling index indicates normal valvular function?

 A. > 7 mL/sec

B. < 7 mL/sec

C. > 5 mL/sec

D. < 2 mL/sec

Definition
D. < 2 mL/sec
Term

What venous filling index is consistent with deep and/or superficial valvular incompetence?

A. > 7 mL/sec

B. < 7 mL/sec

C. > 5 mL/sec

D. < 2 mL/sec

Definition
A. > 7 mL/sec
Term

What do calf raises do and how is venous volume affected?

 A. activates calf muscle pump, inc VV

B. activates calf muscle pump, dec VV

C. inactivates calf muscle pump, inc VV

D. none of the above

Definition
B. activates the calf muscle pump, decreasing venous volume
Term

T or F

 The ejection volume measures the decrease in venous volume achieved with one calf exercise.

Definition
True
Term
This represents the emptying power of a single calf contraction and is measured by emptying volume divided by venous volume time 100.
Definition
Ejection Fraction (EF)
Term
How is residual venous volume determined?
Definition
recording of the volume during performance of 10 tiptoe movements
Term
What does the residual venous volume fraction (RV/VV x 100) represent?
Definition
Total calf blood volume remaining following this level of exercise.
Term

What % represents normal calf muscle pump function?

 

A. > 35%

B. < 10%

C. > 75%

D. < 35%

Definition
D. < 35%
Term

What are 2 benefits of APG testing?

A. evaluate benefit of surgical intervention

B. evaluate effect of noninvasive therapeutic (support stockings) measures

C. all the above

D. none of the above

Definition
C. all of the above
Term

What are the disadvantages of APG?

A. Improper placement of sensor, thick skin, non-intact skin.

B. Requires extensive patient cooperation moving from one position to the next rapidly

C. muscle contraction artifact

D. specific incompetent valves cannot be identified

E. B, C, D are all disadvantages of APG

Definition

E. B, C, D are all disadvantages of APG

 

Term

T or F

Venous ulcers are usually lateral near the ankle and bleed easily.

Definition
False
Term

T or F

Large pulmonary obstructions usually resolve spontaneously.

Definition
False
Term

Acute venous obstruction that is high in the thigh may lead to:

A. Venous claudication

B. Phlegmasia alba dolens

C. Phlegmasia cerulea dolens

D. All of the above

Definition
D. All of the above
Term

T or F

Post-phlebitic syndrome results from venous insufficiency

Definition
False
Term

Secondary effects of pulmonary embolus may be:

A. Pulmonary Hypertension

B. Increased workload for left side of heart

C. Pulmonary edema

D. evidence of post-phlebitic syndrome

Definition
A. Pulmonary Hypertension
Term

Venous hypertension MOST often results from:

A. Deep Venous reflux

B. Valvular sufficiency

C. Pulmonary Embolism

D. Systemic Arterial Hypoxemia

Definition
A. Deep Venous reflux
Term

Symptoms of PE would include:

A. Dyspnea

B. Pleuritic Pain

C. Tachypnea

D. Hemoptysis

E. All of the above

Definition
E. All of the above
Term

Which of the following best describes dyspnea?

A. Fast breathing

B. Difficulty breathing

C. No breathing

D. none of the above

Definition
B. Difficulty breathing
Term

T or F

When a person is suspected of having a pulmonary embolism, it is not likely that a Duplex exam will be ordered.

Definition
False
Term

Diagnosis of a PE can be made by:

A. VQ Scan

B. Pulmonary Angiography

C. Chest X-ray

D. AcuTect

E. All of the above EXCEPT D

Definition
E. All of the above EXCEPT D.
Term

Characteristics that suggest acute thrombus rather than older thrombus include all except:

A. Poorly Attached, floating in the lumen

B. Smooth borders, spongy texture

C. Bright, heterogeneous echoes within the lumen

D. Vessel dilatation

Definition
C. Bright, heterogeneous echoes within the lumen.
Term

T or F

A patient can get post-phlebitic syndrome from a current DVT.

Definition
False
Term

T or F

A patient cannot display valvular incompetencee unless a DVT is present.

Definition
False
Term

T or F

Patients can have venous insufficiency because of valvular incompetence.

Definition
True
Term

T or F

When placing a tourniquet around a limb to test for valvular incompetency the deep veins are occluded.

 

Definition
False
Term

D-Dimer titers detect increased ________ particles.

A. Fibrinogen

B. Plasmin

C. Fibrin

D. Hemeglobin

Definition
C. Fibrin
Term

Air plethysmography requires the patient to be placed in the _______ position.

A. Horizontal

B. Supine

C. Reverse Trendelenberg

D. None of the above

Definition
B. Supine
Term

Indirect methods of venous testing ______ presence of DVT.

A. Prove

B. Show

C. Disprove

D. Indicate

Definition
D. Indicate
Term

T or F

If the VRT is >20 sec with & without a tourniquet you can conclude that the deep system is incompetent.

 

Definition
False
Term

T or F

Abnormal PPG recovery time with the use of a tourniquet indicates the superficial valves are cometent.

Definition
False
Term

T or F

A problem with most APG techniques is that artifacts are produced when the patient cannot perform the proper muscle contraction exercises.

Definition
True
Term

Which of the following statements best describes APG testing?

A. A means to measure volume increase in the lower extremities

B. An invasive method using contrast media

C. Screening test to detect plasmin-lysed fibrin

D. Use of a light emitting diode to measure volume changes

Definition
A. A means to measure volume increase in the lower extremities
Term

An advantage of venous plethysmography is:

A. It is very good at detecting the location of thrombus

B. Thick skin allows for adequate penetration of infrared light.

C. Requires little assistance from the patient

D. None of the above

 

Definition
D. None of the above
Term

Venous plethysmographic testing records the calf volume findings on:

A. Paper

B. Disk

C. Film

D. Strip chart

Definition
D. Strip chart
Term

PPG utilizes:

A. Cuff device placed around the ankle

B. tiptoe movements to test venous residual volume

C. An infrared light emitting diode

D. Reverse Trendelenberg position

 

 

Definition
C. An infrared light emitting diode
Term

Which of the following plethysmographic instrumentation might you see in use today in a vascular lab?

A. D-Dimer

B. AcuTect

C. Photo- and air plethysmography

D. MRI

Definition
C. Photoplethysmography and air plethysmography
Term

T or F

PPG detects actual volume changes and does not detect the presence of red blood cells under the probe.

Definition
False
Term

T or F

An elevated D-Dimer cannot be used alone to make a diagnosis.

Definition
True
Term

T or F

D-Dimer testing will eventually replace Duplex exams as the venous Gold Standard

Definition
False
Term

When testing with PPG to determine superficial or deep venous insufficiency with no tourniquets, abnormal results might indicate:

A. the need to utilize a tourniquet to be able to differentiate.

B. Use a pressure cuff

C. Do no further testing

D. None of the above

Definition
A. the need to utilize a tourniquet to be able to differentiate.
Term

A short venous refill time (< 20 sec) detected on PPG exam can be a result of:

A. No problems

B. DVT

C. Thrombus

D. Venous reflux

Definition
D. Venous reflux
Term

The best definition of varicose veins would be:

A. Abnormally dilated and tortuous deep veins

B. Smooth superficial veins

C. Abnormally dilated and tortuous superficial veins

D. Veins with brightly echoing walls

Definition
C. Abnormally dilated and tortuous superficial veins
Term

Primary varicose veins could occur:

A. Secondary to a congenital deficient valve

B. Secondary to PE

C. Secondary to normal valve

D. None of the above

Definition
A. Secondary to a congenital deficient valve
Term

Which of the following is a defining characteristic of secondary varicose veins?

A. Congenitally deficient vein valves

B. Incompetent and dilated perforators

Definition
B. Incompetent and dilated perforators
Term

T or F

At one time contrast venography was regarded as the "Gold Standard" for the detection of DVT in the lower extremities.

Definition
True
Term

T or F

Venographic characteristics of acute DVT is radically different than on Duplex.

Definition
False
Term

T or F

AcuTect is performed in the vascular lab to diagnose DVT

 

Definition
False
Term

T or F

AcuTect binds to the surfaces of activated platelets and is therefore a good indicator of chronic venous thormbosis.

Definition
False
Term

T or F

Radioactive markers are placed on the patient during contrast venography

Definition
False
Term

T or F

When a filling deficit is found with contrast venography, only one view is needed to verify that DVT is present.

Definition
False
Term

As contrast media moves up the leg in contrast venography, a DVT will appear as:

C. A contrast filling deficit

Definition
C. A contrast filling deficit
Term

When a contrast venography exam is performed and there is lack of contrast in the entire deep system from multiple views, this is suggestive of:

A. Massive presence of DVT

 

Definition
A. Massive presence of DVT
Term

Which of the following PPG traces would be indicative of normal VRT?

[image]

A. RT = 24 sec

B. RT = 6 sec

Definition
A. RT = 24 sec
Term

The following PPG exam was completed on a 32 year old female patient.  The top strip recording was a result with no tourniquet application and the bottom was with tourniquet.  What can you interpret?

[image]

A. Deep vein incompetency

B. Superficial vein incompetency

C. Both A & B

Definition
A. Deep vein incompetency
Term

T or F

Patients with Grade III venous insufficiency would present with symptoms of pain and swelling with a VRT of >20 sec.

Definition
False
Term

T or F

Patients with Grade I venous insufficiency would experience VRT of <10 sec.

Definition
False
Term

T or F

When performing APG, maximum venous emptying occurs after the patient has completed a series of 10 toe-ups.

Definition
False
Term

T or F

APG is routinely performed in all vascular labs across the nation.

Definition
False
Term

T or F

When conducting testing with APG, a VFI of greater than 7 ml/sec is desirable.

Definition
False
Term
Why do we use prophylactic measures?
Definition
To reduce venous stasis or coagulability of blood
Term
What are 4 medical ways to prevent stasis?
Definition

Elevation

Mechanical Pedaling

Pneumatic Devices

Elastic compression

Term

T or F

Patients who are mobile have increased incidence of thromboembolism

Definition
False, reduced incidence
Term
What position is best during surgery to assist venous flow?
Definition
Trendelenberg
Term

Passive dorsiflexion of the foot during surgery to reduce incidences of DVT describes what type of stasis prevention?

A. Pneumatic Devices

B. Exercise

C. Mechanical Pedaling

D. Elevation

Definition
C. Mechanical pedaling
Term

Multiple diaphragm cuff fitting the whole calf with an air pump at the foot of the bed describes what type of stasis prophylaxis?

A. Pneumatic Devices

B. Exercise

C. Mechanical Pedaling

D. Elevation

Definition
A. Pneumatic devices
Term

Stockings, with max compression at the foot and minimal at the thigh, used to collapse the superficial veins and increase flow in the deep system describe what type of stasis preventive measure?

A. Pneumatic Devices

B. Exercise

C. Mechanical Pedaling

D. Elastic compression

Definition
D. Elastic compression
Term

What are 4 medications used to help prevent coagulation?

 

Definition

ASA (aspirin)

Heparin

Warfarin (Coumadin)

Lovenox

Term

What type of drug is aspirin?

A. anticoagulant

B. antiplatelet

Definition
B. Antiplatelet
Term

T or F

A patient already being anticoagulated usually is also on ASA

Definition
False, usually not also on ASA
Term

What are complications of ASA use?

A. Leukocytopenia

B. Thrombocytopenia, gastrointestinal bleeds

C. anemia, hemophilia

D. lymphocytopenia

Definition
B. Thrombocytopenia, gastrointestinal bleeds
Term

What is one of the most widely used drug for vascular patients?

A. ASA

B. Coumadin

C. Heparin

D. Lovenox

Definition
C. Heparin
Term
How does Heparin work to assist with anticoagulation?
Definition
augments the action of antithrombin III
Term

T or F

When given in adequate amounts heparin prevents formation and/or extension of thrombi.

Definition
True
Term
What is "a dose higher than the average or maintenance doses, used at the initiation of therapy to rapidly establish a desired level of the drug" called?
Definition
Loading dose
Term

T or F

In prophylactic measures, the loading and maintenance doses are unequal.

Definition
False, they are equal
Term
For DVT treatment, what drug is given via an IV loading dose bolus followed by maintenance doses given 2-3 times a day until patient is ambulatory?
Definition
Heparin
Term

How long is Heparin therapy maintained for?

A. 1-2 days

B. 2 weeks

C. 3-5 days

D. 5-7 days

Definition
D. 5-7 days
Term

 T or F

The patient's anticoagulant response must be closely monitored to avoid complications during heparin therapy.

Definition
True
Term

T or F

Coumadin is probably long term treatment.

Definition
True
Term

T or F

Coumadin is an oral anticoagulation with Warfarin.

Definition
True
Term
How does Coumadin work in anticoagulation process?
Definition
Inhibits the synthesis of vitamin K dependent clotting factors by the liver.
Term

T or F

An effective dose of Coumadin prevents clotting without bleeding complications.

 

Definition
True
Term

T or F

Patients with DVT/PE may require long term therapy to prevent recurrent disease.

Definition
True
Term

After the first episode of DVT/PE what is the minimum treatment length?

A. 1 month

B. 7-9 months

C. 1 year

D. 3-6 months

Definition
D. 3-6 months
Term

T or F

With recurring episodes, other risk factors indicate indefinite Coumadin therapy.

Definition
True
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