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Life Science I
Ground Rules of Metabolism
50
Biology
Undergraduate 1
03/05/2011

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Term
The liver plays a central role in
Definition
alcohol metabolism
Term
consumption of too much alcohol
Definition
can lead to alcoholic hepatitis or alcoholic cirrhosis
Term
First law of thermodynamics
Definition
energy cannot be created or destroyed
Term
the total amount of energy in the universe remains
Definition
constant
Term
energy can undergo conversions from one form to another, but
Definition
it cannot be created or destroyed
Term
What is energy?
Definition
capacity to do work
Term
forms of energy
Definition
potential, kinetic, chemical
Term
potential energy
Definition
capacity to do work because of something's location and the arrangement of its parts
Term
kinetic energy
Definition
energy of motion
Term
chemical energy
Definition
potential energy of molecules
Term
Second law of thermodynamics
Definition
energy tends to flow from concentrated to less concentrated forms
Term
the cost of concentrating it n one area comes at a greater cost of
Definition
energy dispersal or dilution somewhere else
Term
the total amount of energy is
Definition
flowing from high-energy forms to forms lower in energy
Term
life's primary energy source
Definition
the sun
Term
producers
Definition
trap energy from the sun and convert it into chemical bond energy
Term
all organisms use the energy stored in the bonds of
Definition
organic compounds to do work
Term
Nutrients cycle
Definition
between producers ans consumers
Term
entropy
Definition
measure of degree of disorder in a system
Term
as systems lose energy they become
Definition
more disorganized
Term
The world of life maintains a high degree of organization because
Definition
it is replenished with energy from the sun
Term
the molecules of life do not
Definition
form spontaneously
Term
metabolism
Definition
it takes net inputs of energy to force small molecules to combine into larger ones
Term
Reactants-->
Definition
products
Term
Participants in Metabolic Reactions
Definition
reactants, intermediates, products, ATP/Energy carriers, enzymes, cofactors, transport proteins
Term
endergonic reactions
Definition
energy input required
Term
product has more energy than starting substances
Definition
endergonic reactions
Term
exergonic reactions
Definition
energy is released
Term
products have less energy than starting substance
Definition
exergonic reactions
Term
cells "earn" ATP in
Definition
exergonic reactions
Term
cells "spend" ATP in
Definition
endergonic reactions
Term
When ATP gives up a phosphate group
Definition
ADP forms
Term
ATP can re-form when
Definition
ADP binds to inorganic phosphate or to a phosphate group that was split from a different molecule
Term
regenerating ATP by this ATP/ADP cycle helps
Definition
drive most metabolic reactions
Term
enzymes
Definition
catalytic molecules
Term
reactions do not alter or use up
Definition
enzyme molecules
Term
The same enzyme usually works for
Definition
both the forward and reverse reactions
Term
each type of enzyme recognizes and binds to
Definition
only certain substrates
Term
activation energy
Definition
the minimum amount of energy required to get any reaction to the point where it will run spontaneously. with no further energy input
Term
for a reaction to occur, an energy barrier must be surmounted
Definition
activation energy
Term
enzymes lower
Definition
activation energy
Term
substrate molecules are
Definition
brought together
Term
active sites
Definition
may promote acid-base reactions
Term
A cellular change, caused by a specific activity, shuts down the
Definition
activity that brought it about
Term
factors influencing enzyme activity
Definition
temperature, pH, salt concentration, allosteric regulators, co-enzymes and cofactors
Term
small increase in temperature increases
Definition
molecular collisions, reaction rates
Term
high temperatures
Definition
disrupt bonds and destroy the shape of active site
Term
co-enzymes
Definition
accept electrons and hydrogen ions
Term
metabolic pathways
Definition
defined as enzyme-mediated sequences of reactions in cells
Term
biosynthetic
Definition
photosynthesis
Term
degradative
Definition
aerobic respiration
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