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LIFE 102 Test 3
Chapter 14 (Genetics)
17
Biology
Undergraduate 1
04/11/2012

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Term
Character (def)
Trait (def)
Definition
Character - Distinct heritable feature
Trait - character variants
Term
True-Breeding (def)
Definition
Plants that produce offspring of the same variety when they self-pollinate
Term
Hybridization (def)
P, F1 & F2 Generations (def)
Definition
Hybridization - Mating of two contrasting true-breeding varieties
P - True-breeding parents
F1 - hybrid offspring of the P generation
F2 - F1 individuals self-pollinate to produce the F2 generation
Term
Mendel's 4 concepts to explain inheritance pattern
Definition
- Alleles, alternate version of genes account for inherited characters
- Each organism inherits two alleles of each character
- If two alleles at a locus differ, one is dominant, the other recessive; dominant is expressed, recessive has no effect
- Law of Segregation; the two alleles separate during gamete formation
Term
Homozygous (def)
Heterozygous (def)
Definition
Homo - two identical alleles for a character is homozygous for gene controlling that character
Hetero - Two different alleles for a gene, not true-breeding
Term
Phenotype (def)
Genotype (def)
Definition
Phenotype - physical appearance, expressed characteristics
Genotype - genetic makeup, assortment of alleles
Term
Testcross (Def)
Definition
Breeding an individual displaying a dominant trait with a homozygous recessive individual
If any offspring are homozygous recessive, the parent must be heterozygous
Term
Law of Independent Assortment (def/proof)
Definition
- Each pair of alleles segregates independently of each other pair of alleles during gamete formation
- Technically only applies to alleles on
Proof - Dihybrid cross, 9:3:3:1 ratio only possible if the two traits are sorted individually
Term
Deviation from Mendelian patterns, 3 situations
Definition
- Alleles not completely dominant or recessive
- When a gene has more than two alleles
- When a gene produces multiple phenotypes
Term
Complete Dominance (def)
Incomplete Dominance (def)
Codominance (def)
Definition
Complete - When phenotype of homozygous and heterozygous individuals is identical
Incomplete - Phenotype is somewhere between the phenotypes of the two parental varieties
Codominance - two dominant alleles affect the phenotype in separate, distinguishable ways
Term
Pleiotropy (def)
Definition
Single genes often have multiple phenotypic effects
Responsible for multiple symptoms of certain hereditary disease
Term
Epistasis (def)
Definition
A gene at one locus alters the phenotypic expression of a gene at a second locus
Term
Quantitative characters (def)
Polygenic inheritance (def)
Definition
Quant - traits that vary in the population along a continuum
Polygenic - an additive effect of two or more genes on a single phenotype, indicated by a quantitative character (e.g. skin color)
Term
Norm of reaction (def)
Definition
The phenotypic range of a genotype influenced by the environment
e.g. Flowers with the same genotype can have different color depending on outside factors
Term
Multifactorial (def)
Definition
Characters that vary based on genetic and environmental factors
Term
Cystic fibrosis
Definition
- Most common lethal genetic disease in US, 1:2500 people of European descent
- Defective or absent chloride transport channels in plasma membranes
Term
Sickle-cell disease
Definition
- Affects 1:400 African-Americans
- Single amino acid in hemoglobin protein differs
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