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Lecture 9
Important Terms
26
Biology
Undergraduate 2
10/09/2011

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Term
Pentose Sugar
Definition
A five-carbon sugar that is one of the three parts of a nucleotide (Deoxyribose and Ribose)
Term
Phosphate Group
Definition
An acidic chemical component that is one of the three parts of a nucleotide
Term
Nitrogenous Base
Definition
A nitrogen containing purine or pyrimidine that is one of the three components of a nucleotide
Term
Type R
Definition
Nonvirulent bacteria
Term
Type S
Definition
Virulent bacteria
Term
Purine
Definition
One of the two types of cyclic nitrogenous bases found in DNA and RNA. Bicyclic (Adenine and Guanine)
Term
Pyrimidine
Definition
One of the two types of cyclic nitrogenous bases found in DNA and RNA. Unicyclic (Thymine, Cytosine, and Uracil)
Term
Phosphodiester Bond
Definition
A covalent bond in RNA and DNA between a sugar of one nucleotide and a phosphate group of an adjacent nucleotide
Term
5' End
Definition
Phosphate group end of DNA and RNA
Term
3' End
Definition
Pentose sugar end of DNA and RNA
Term
Nucleotide
Definition
The type of monomeric molecule found in RNA and DNA. Consist of a pentose sugar, a nitrogenous base and a phosphate group
Term
Bidirectional
Definition
Synthesis of DNA in both directions away from an origin of replication
Term
Semi-conservative
Definition
A model for DNA replication in which each daughter molecule retains one of the parental strands
Term
Semi-discontinous
Definition
Concerning DNA replication, when one new strand is synthesized continuously and the other strand is synthesized discontinuously
Term
Leading Strand
Definition
In DNA replication, the DNA strand that is synthesized continuously from a single RNA primer in the same direction as movement of the replication fork
Term
Lagging Strand
Definition
In DNA replication, the DNA strand that is synthesized discontinuously from multiple RNA primers in the direction opposite to movement of the replication fork
Term
Replication Fork
Definition
A Y-shaped structure formed when a double-stranded DNA molecule unwinds to expose two single-stranded template strands for DNA replication
Term
Okazaki Fragments
Definition
The short, single-stranded DNA fragments that are synthesized on the lagging-strand template during DNA replication and are subsequently covalently joined to make a continuous strand
Term
DNA Polymerase I
Definition
Synthesizes DNA in a 3' to 5' direction and from 5' to 3' replaces RNA primers with DNA
Term
DNA Polymerase III
Definition
Synthesizes DNA in a 3' to 5' direction
Term
Gyrase
Definition
Undoes supercoiling
Term
Initiator Proteins
Definition
Bind origin of replication
Term
DNA Helicase
Definition
Denatures DNA
Term
Single Stranded DNA Binding Proteins
Definition
Prevent Reannealing
Term
DNA Primase
Definition
Initiates a short RNA primer
Term
DNA Ligase
Definition
Seals the nick between two adjacent fragments on the lagging strand
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