Tuberculosis (TB), metastases to pericardium from breast in women or lung in men

Often gram positive cocci, Neisseria mengitidis (gram negative cocci)

Distant heart sounds, most common known cause radiation as in patient with Hodgkin lymphoma involving the mediastinum or radiation for lung cancer or to chest wall in a female patient with breast cancer

Rapid accumulation of fluid or blood in the pericardium – most common cause metastatic carcinoma