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Lecture 28
brock
12
Microbiology
Undergraduate 3
04/08/2014

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Term
activator
Definition
regulatory protein that enhances binding of RNA polymerase to DNA
Term
inducer
Definition
activator protein cannot bind to DNA without _________
Term
activator-binding site
Definition
where activator binds to DNA and controls/ allows transcription
Term
regulon
Definition
multiple operons controlled by the same regulatory protein
Term
global control systems
Definition
regulatory mechanisms that respond to environmental signals by regulating the expression of many different genes
Term
catabolite repression
Definition
mechanism of global control that decides between utilizing different available carbon sources
Term
diauxic growth
Definition
2 exponential growth phases, usually a result of catabolite repression
Term
cyclic AMP receptor protein (CRP)
Definition
activator for catabolite repression

genes that encode a catabolite-repressible enzyme are only expressed if ______ binds to DNA in the promoter region
Term
cyclic adenosine monophosphate (cyclic AMP ) (cAMP)
Definition
regulatory nucleotide that binds to CRP which allows CRP to then bind to DNA

glucose inhibits its synthesis
Term
regulatory nucleotide
Definition
nucleotide molecule used in metabolite control (ex; cAMP)
Term
adenylate cyclase
Definition
enzyme that synthesizes cAMP from ATP
Term
NrpR
Definition
represses genes involved in nitrogen metabolism in archaea
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