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Lecture 21
brock
18
Microbiology
Undergraduate 3
04/08/2014

Additional Microbiology Flashcards

 


 

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Term
~300 amino acids
Definition
how big is average protein
Term
gene families
Definition
groups of genes with related functional products
Term
horizontal (lateral) gene transfer
Definition
genes arise from other organisms, often detected by G-C content
Term
pathogenicity islands
Definition
large unstable regions of the genome capable of horizontal gene transfer
Term
plasmids
Definition
extrachromosomal genetic elements that replicate independently of the host chromosome but need host enzymes for replication
Term
plasmid incompatibility
Definition
two closely related extrachromosomal genetic elements cannot be maintained in the same host cell
Term
episomes
Definition
plasmids that can integrate into the cell's chromosome
(note: integrated virus = prophage)
Term
curing
Definition
process by which cells have their plasmids removed
Term
conjugative plasmids
Definition
extrachromosomal genetic elements capable of transferring themselves via cell-to-cell contact
Term
R plasmids (resistance plasmids)
Definition
widespread plasmids that confer resistance to antibiotics and other growth inhibitors
Term
ability of pathogen to attach to and colonize specific host tissue and production of toxins, enzymes, and other molecules that damage host
Definition
what characteristics to plasmids encode for that cause virulence?
Term
bacteriocins
Definition
protein antibiotics that inhibit or kill other bacteria
Term
semiconservative
Definition
the way in which replication occurs so each new double strand consists of one parental and one new strand
Term
template
Definition
DNA strand used to make complementary daughter strand
Term
DNA polymerase
Definition
enzymes that catalyze the addition of deoxynucleotides
Term
DNA polymerase III
Definition
primary enzyme for replication in E. coli
Term
primer
Definition
nucleic acid molecule to which DNA polymerase can attach the first nucleotide
(basically short stretch of RNA about 11-12 nucleotides long)
Term
primase
Definition
RNA-polymerizing enzyme that makes the RNA primer
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