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Lecture 1
N/A
10
Biology
Undergraduate 2
02/04/2012

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Term
Population Genetics and Evolution
Definition
Diversity of alleles and new alleles resulting from mutation allow species to adapt to change. Allele frequencies reach equilibrium in population if certain criteria are met. Quantitative trait loci = certain traits controlled by multiple genes. Other genes resulted in taller, single cob, with multiple seed rows.
Term
How much of the human genome is variable?
Definition
15 million bases, which is 0.5% of the genome (full genome = 30 bill bases).
Term
Statistics of Genetic Disorders
Definition
~5% of people born will have a genetic disorder by age 25. 0.36% = single gene disorders, 0.18% = chromosome abnormalities, 4.64% = multifactorial disorders (many genes responsible), and 0.12% have unknown disorders. Multifactorials can't be understood till the individual genes are.
Term
Domestication of Maize 6000-10000 Years Ago
Definition
Only 5 genes are different between teosinte and corn. The tga1 gene is active in teosinte giving it a hard, brown casing but a single amino acid difference got rid of that casing in modern corn.
Term
Pea Flower Anatomy
Definition
Anthers = male. Stigma = female. Remove anthers, selectively pollinate stigmas.
Term
Mendel's Peas
Definition
7 characteristics (genes) determined by pairs of traits (alleles) that didn't show incomplete dominance - peas were either yellow or green, not yellow-green, etc. DNA IDs of these traits (wrinkled, stem length, green, and white flower) are now known.
Term
Monohybrid Crosses
Definition
P = (pure-breeding dominant)*(pure-breeding recessive). F1 = heterozygous, show dominant phenotype. F2 = 1:4 homozygous dominant, 2:4 heterozygous, 1:4 homozygous recessive.
Term
Law of Segregation
Definition
During gamete formation, alleles of each parent separate. Two alleles/gametes, one from each parent, unite at random at fertilization. Dominant one determines phenotype.
Term
Test crosses
Definition
Cross A: dominant phenotype (unknown homozygous) to recessive phenotype. Cross B: dominant phenotype (unknown heterozygous) to recessive phenotype. Cross A results in all heterozygous dominant phenotype. Cross B results in 1:1 dominant (hetero) to recessive.
Term
Mendel's Law of Independent Assortment
Definition
During gamete formation, different pairs of alleles segregate independently of each other.
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