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Lect 5
Allergy
29
Medical
Graduate
02/20/2013

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Cards

Term
50% of cases of allergic conjunctivitis will be due to…
Definition
SAC (Seasonal Allergic Conjunctivitis)
Term
Eczema and asthma have a strong association with what type of ocular allergy?
Definition
Atopic Keratoconjunctivitis (AKC)
Term
When Al Lergen shows up at your house and meets your roommate MC, who does MC text to make the party rockin'?
Definition
His Tamines
Term
Are topical antihistamines vasoconstrictive or vasodilative?
Definition
Vasoconstrictive
Term
Why are antihistamines short duration?
Definition
Because they don't prevent inflammation or the release of the histamines in the first place - they just take care of what's already there.
Term
Topical antihistamines are not approved for folks under __ years old.
Definition
3 years old
Term
What's the biggest difference between Livostin and Emadine, our two topical antihistamines?
Definition
Mainly potency. Emadine is supposedly 5000 times more potent than Livostin.
Term
Mast cell stabilizers prevent inflow of _________.
Definition
calcium
Term
Mast cell stabilizing antihistamines are not approved for folks under __ years old.
Definition
2 or 3 years old
Term
Patanol and Pataday are examples of what kind of drop?
Definition
Mast Cell Stabilizing Antihistamines

Pataday is once a day
Term
This mast cell stabilizing antihistamine stings like a mother.
Definition
Optivar
As in, I would like to stay as (opti)var away from this painful drop as I can.
Term
This MC stabilizing antihistamine makes a point of advertising that it's an H1 histamine receptor antagonist.
Definition
Lastacaft (alcaftadine 0.25%)
Term
What's the big deal about the MC stabilizing antihistamine Ketotifen fumarate 0.025%?
Definition
*****
It's OTC
*****
Because of this, it's always a good thing to name drop this one to patients, even if you Rx a different MC stabilizer.
Term
What type of drop is particularly helpful in severe cases of VKC, AKC, GPC, and allergic contact dermatitis?
Definition
Topic steroids
Term
What caveat must you keep in mind when treating an ocular allergic situation with topical steroids?
Definition
*****
Steroids should be limited to ACUTE suppression of symptoms
*****

This is because of the potential for side effects
Term
Lotemax and Alrex are topical steroids for tx of ocular allergies, but it's important to remember that they are rarely ____________ ________.
Definition
prescribed alone

Ideally, put the patient on a mast-cell stabilizer near the beginning of the steroid treatment.
Term
What's the only NSAID approved for the treatment of (I'm assuming ocular) itch?
Definition
Acular (ketorolac tromethamine 0.5%)
Term
What are the two topical NSAIDs that we might pull out of our utility belt (assuming we are ODs /and/ Batman (which is to say, assuming we're Dax))?
Definition
Acular (ketorolac) and Voltaren (diclofenac)
Term
What are some downsides to topical decongestants?

Are topical decongestants really the best choice for ocular allergy? Really? …Really??

REALLY?????
Definition
(Think about Visene for these)
Rebound redness
Dilation
C/I for narrow-angle glaucoma
…and more!

Really… no. Overall, they're not the best choice. They don't last very long and have a handful of side-effects including that rebound redness.
Term
What's the active ingredient in Visene?
Definition
Tetrahydrozoline (Not phenyl?!! *mind blown*)
Term
Chronic use of this type of ocular allergy drop can lead to toxic, follicular reactions or even a contact dermatitis.
Definition
Antihistamine-Decongestant Combos
Term
When you hear oral antihistamines, you should probably go ahead and think _____ _____.
Definition
dry eyes

'Sleepy head' (diphenhydramine (Benadryl)) would have been an ok answer, but loratadine (Claritin) did some work to kick that.
Term
First-generation prescription mast cell stabilizers (eg. lodoxamide or cromolyn sodium) are approved for one thing and one thing only. What is that one thing?
Definition
*****
VKC
*****
Term
Would it be best to start prescription mast cell stabilizers before the allergy season at all or right when you start experiencing symptoms?
Definition
Start 1 week before the season begins since it takes 1-2 weeks for them to kick in fully.
Term
What kind of drop is Alocril (nedcromil sodium 2%) and what is its dosing?
Definition
It's a prescription mast cell stabilizer.

*****
Sig: bid
*****
Term
What kind of drug is Zyrtec (cetirizine) and how can you get a hold of it?
Definition
Oral antihistamine

***** (as written in the PPT)
OVER THE COUNTER
(30 TABS FOR $20 ($0.67 / TAB)
*****
Term
Do you need a prescription for Allegra? (An oral antihistamine)
Definition
*****
No - Allegra is now OTC
*****
Term
A patient comes into your office with "itchy eyes." What clinical pearls did Dr. Horn drop on us about this?
Definition
First, if the patient is actually seeking medical care, the severity is probably moderate at least.

Second, distinguish between itching and burning, because the patient may get them mixed up.
Term
What would you prefer a patient use between oral antihistamines and nasal sprays?
Definition
Go for nasal sprays, since the orals tend to end up with dry eye side effects.
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