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Lec. 10: Membrane Structure and Function
Chapter 7 BIO 202
19
Biology
Undergraduate 2
02/15/2012

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Term
Plasma Membrane
Definition
surrounds living cells
separates from surroundings
selectively permeable
composed of phospholipids and proteins
Molecules that compose it are often amphipathic
Term
Amphipathic molecule
Definition
has both hydrophobic and hydrophilic regions
ex. Phospholipids and membrane proteins
Term
Phospolipids
Definition
Glycerol + 2 fatty acids + 1 phosphate

-can move laterally within the plasma membrane
Term
Functions of Membrane Proteins
Definition
-transport
-enzymatic activity
-signal transduction
-intercellular joining
-cell-cell recognition
-attachment to the cytoskeleton and the extracellular matrix (ECM)
Term
Unsaturated Fatty Acids effect on Melting Point and Fluidity
Definition
have lower melting point/ more fluid at lower temperatures
do not pack tightly
Term
Hypertonic solution
Definition
higher concentration of solutes
Term
Hypotonic solution
Definition
lower concentration of solutes
Term
Isotonic solution
Definition
solute concentrations are equal
Term
Passive transport
Definition
diffusion across membrane without spending energy

ex. During respiration, O2 diffuses across the cellular membrane
Term
Active transport
Definition
The movement of a solute across a biological membrane such that the movement is directed upward in a concentration gradient (against the gradient)
Requires expenditure of energy
energy supplied by hydrolysis of ATP
Term
Osmosis
Definition
movement of water or another solvent across a semipermeable membrane from a region of low solute concentration to one of higher solute concentration
Term
Facilitated Diffusion (mediated transport)
Definition
movement of a solute across a biological membrane that requires the participation of one or more transport agents (ie. protein)

Can be passive, along concentration gradient
Can be active, against a concentration gradient
Term
Cotransport
Definition
simultaneous transport of two different substances across a biological membrane
Term
Exocytosis
Definition
the cell secretes (exports) macromolecules by fusion of vesicles with the plasma membrane
Term
Endocytosis
Definition
the cell IMPORTS macromolecules by forming new vesicles from the plasma membrane
reverse of exocytosis
Term
Phagocytosis
Definition
Type of endocytosis
A vacuole is formed with a lysosome for digestion
Term
Pinocytosis
Definition
Type of endocytosis
Soluble materials (NON-SPECIFIC) are taken up into vesicles for digestion
Term
Receptor-mediated endocytosis
Definition
Type of endocytosis
Receptor-mediated endocytosis is SPECIFIC.
Process by which specific substances are brought into the cell that are in low concentration or to be used in specific cell types.
Term
Membrane model
Definition
Phospholipids are arranged in the bilayer of the membrane like this: hydrophobic fatty acid chains directed inward on either side and hydrophilic phosphate groups directed outward on either side.
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